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CATH Superfamily 3.40.50.150

Vaccinia Virus protein VP39

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Vaccinia Virus protein VP39
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 9: 23S rRNA (Uracil(1939)-C(5))-methyltransferase Rlm...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
RRNA (uridine-C5-)-methyltransferase activity GO:0070041
Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing C5-methyluridine.
 33 O31503 (/IDA) O31503 (/IDA) O31503 (/IDA) O31503 (/IDA) O31503 (/IDA) P55135 (/IDA) P55135 (/IDA) P55135 (/IDA) P55135 (/IDA) P55135 (/IDA)
(23 more)
4 iron, 4 sulfur cluster binding GO:0051539
Interacting selectively and non-covalently with a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.
 27 P55135 (/IDA) P55135 (/IDA) P55135 (/IDA) P55135 (/IDA) P55135 (/IDA) P55135 (/IDA) P55135 (/IDA) P55135 (/IDA) P55135 (/IDA) P55135 (/IDA)
(17 more)
RRNA methyltransferase activity GO:0008649
Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a nucleoside residue in an rRNA molecule.
 6 Q9KPC1 (/ISS) Q9KPC1 (/ISS) Q9KPC1 (/ISS) Q9KPC1 (/ISS) Q9KPC1 (/ISS) Q9KPC1 (/ISS)
S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity GO:0030697
Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing thymine at position U54 of a transfer RNA. This occurs in most Gram-negative bacteria, some archae, and eukaryotes.
 3 O58864 (/ISS) Q8U1N4 (/ISS) Q8U1N4 (/ISS)
RRNA (uridine-C5-)-methyltransferase activity GO:0070041
Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing C5-methyluridine.
 3 O58994 (/ISS) Q8U2K7 (/ISS) Q8U2K7 (/ISS)
S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity GO:0030697
Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing thymine at position U54 of a transfer RNA. This occurs in most Gram-negative bacteria, some archae, and eukaryotes.
 1 Q9UZR7 (/IDA)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
RRNA base methylation GO:0070475
The addition of a methyl group to an atom in the nucleoside base portion of a nucleotide residue in an rRNA molecule.
 27 P55135 (/IDA) P55135 (/IDA) P55135 (/IDA) P55135 (/IDA) P55135 (/IDA) P55135 (/IDA) P55135 (/IDA) P55135 (/IDA) P55135 (/IDA) P55135 (/IDA)
(17 more)
RRNA modification GO:0000154
The covalent alteration of one or more nucleotides within an rRNA molecule to produce an rRNA molecule with a sequence that differs from that coded genetically.
 6 Q9KPC1 (/ISS) Q9KPC1 (/ISS) Q9KPC1 (/ISS) Q9KPC1 (/ISS) Q9KPC1 (/ISS) Q9KPC1 (/ISS)
RRNA methylation GO:0031167
The posttranscriptional addition of methyl groups to specific residues in an rRNA molecule.
 6 O31503 (/IDA) O31503 (/IDA) O31503 (/IDA) O31503 (/IDA) O31503 (/IDA) Q9UZK1 (/IDA)
TRNA methylation GO:0030488
The posttranscriptional addition of methyl groups to specific residues in a tRNA molecule.
 3 O58864 (/ISS) Q8U1N4 (/ISS) Q8U1N4 (/ISS)
RRNA methylation GO:0031167
The posttranscriptional addition of methyl groups to specific residues in an rRNA molecule.
 3 O58994 (/ISS) Q8U2K7 (/ISS) Q8U2K7 (/ISS)
Response to cold GO:0009409
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
 1 Q9LU28 (/IMP)
TRNA methylation GO:0030488
The posttranscriptional addition of methyl groups to specific residues in a tRNA molecule.
 1 Q9UZR7 (/IDA)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.