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CATH Superfamily 3.40.50.150

Vaccinia Virus protein VP39

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Vaccinia Virus protein VP39
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 9: 23S rRNA (Uracil(1939)-C(5))-methyltransferase Rlm...

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
23S rRNA (uracil(1939)-C(5))-methyltransferase. [EC: 2.1.1.190]
S-adenosyl-L-methionine + uracil(1939) in 23S rRNA = S-adenosyl-L- homocysteine + 5-methyluracil(1939) in 23S rRNA.
  • The enzyme specifically methylates uracil(1939) at C(5) in 23S rRNA.
  • The enzyme contains an [4Fe-4S] cluster coordinated by four conserved cysteine residues.
 1632 A0A061KTT3 A0A061KTT3 A0A061KTT3 A0A061KTT3 A0A061KTT3 A0A061KTT3 A0A061KTT3 A0A061KTT3 A0A061KTT3 A0A061KTT3
(1622 more...)
23S rRNA (uracil(747)-C(5))-methyltransferase. [EC: 2.1.1.189]
S-adenosyl-L-methionine + uracil(747) in 23S rRNA = S-adenosyl-L- homocysteine + 5-methyluracil(747) in 23S rRNA.
  • The enzyme specifically methylates uracil(747) at C(5) in 23S rRNA.
 31 A0A162QZE9 A0A162QZE9 A0A162QZE9 A0A162QZE9 A0A162QZE9 A0A1B2B2W5 A0A1B2B2W5 A0A1B2B2W5 A0A1B2B2W5 A0A1B2B2W5
(21 more...)
TRNA (uracil(54)-C(5))-methyltransferase. [EC: 2.1.1.35]
S-adenosyl-L-methionine + uracil(54) in tRNA = S-adenosyl-L-homocysteine + 5-methyluracil(54) in tRNA.
  • Unlike this enzyme, EC 2.1.1.74 uses 5,10-methylenetetrahydrofolate and FADH(2) to supply the atoms for methylation of U54.
 6 I6V1L9 I6V1L9 O58864 Q8U1N4 Q8U1N4 Q9UZR7