The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Vaccinia Virus protein VP39
".
FunFam 25: N-terminal Xaa-Pro-Lys N-methyltransferase 1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 11 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
N-terminal protein N-methyltransferase activity GO:0071885
Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to the alpha-amino group of the N-terminal amino or imino acid residue of a protein substrate. For example, yeast Tae1p and mammalian family member METTL11A preferentially modify the N-terminal residue of substrates with the N-terminal sequence X-Pro-Lys, where X can be Pro, Ala, or Ser.
|
21 |
P38340 (/IDA)
P38340 (/IDA)
P38340 (/IDA)
P38340 (/IDA)
P38340 (/IDA)
P38340 (/IDA)
P38340 (/IDA)
P38340 (/IDA)
Q6NN40 (/IDA)
Q6NN40 (/IDA)
(11 more) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
13 |
Q6NN40 (/IPI)
Q6NN40 (/IPI)
Q9BV86 (/IPI)
Q9BV86 (/IPI)
Q9BV86 (/IPI)
Q9BV86 (/IPI)
Q9BV86 (/IPI)
Q9BV86 (/IPI)
Q9BV86 (/IPI)
Q9BV86 (/IPI)
(3 more) |
|
Histone methyltransferase activity GO:0042054
Catalysis of the reaction: S-adenosyl-L-methionine + histone = S-adenosyl-L-homocysteine + methyl-histone. Histone methylation generally occurs on either an arginine or lysine residue.
|
13 |
Q6NN40 (/IDA)
Q6NN40 (/IDA)
Q9BV86 (/IDA)
Q9BV86 (/IDA)
Q9BV86 (/IDA)
Q9BV86 (/IDA)
Q9BV86 (/IDA)
Q9BV86 (/IDA)
Q9BV86 (/IDA)
Q9BV86 (/IDA)
(3 more) |
|
Protein methyltransferase activity GO:0008276
Catalysis of the transfer of a methyl group (CH3-) to a protein.
|
12 |
Q8R2U4 (/IDA)
Q9BV86 (/IDA)
Q9BV86 (/IDA)
Q9BV86 (/IDA)
Q9BV86 (/IDA)
Q9BV86 (/IDA)
Q9BV86 (/IDA)
Q9BV86 (/IDA)
Q9BV86 (/IDA)
Q9BV86 (/IDA)
(2 more) |
|
Histone methyltransferase activity GO:0042054
Catalysis of the reaction: S-adenosyl-L-methionine + histone = S-adenosyl-L-homocysteine + methyl-histone. Histone methylation generally occurs on either an arginine or lysine residue.
|
9 | B1H2P7 (/ISS) D2H163 (/ISS) Q2T9N3 (/ISS) Q4KL94 (/ISS) Q4KLE6 (/ISS) Q4KLE6 (/ISS) Q5BJX0 (/ISS) Q6NWX7 (/ISS) Q8R2U4 (/ISS) |
|
N-terminal protein N-methyltransferase activity GO:0071885
Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to the alpha-amino group of the N-terminal amino or imino acid residue of a protein substrate. For example, yeast Tae1p and mammalian family member METTL11A preferentially modify the N-terminal residue of substrates with the N-terminal sequence X-Pro-Lys, where X can be Pro, Ala, or Ser.
|
9 | B1H2P7 (/ISS) D2H163 (/ISS) Q2T9N3 (/ISS) Q4KL94 (/ISS) Q4KLE6 (/ISS) Q4KLE6 (/ISS) Q5BJX0 (/ISS) Q6NWX7 (/ISS) Q8R2U4 (/ISS) |
|
Protein methyltransferase activity GO:0008276
Catalysis of the transfer of a methyl group (CH3-) to a protein.
|
8 | B1H2P7 (/ISS) D2H163 (/ISS) Q2T9N3 (/ISS) Q4KL94 (/ISS) Q4KLE6 (/ISS) Q4KLE6 (/ISS) Q5BJX0 (/ISS) Q6NWX7 (/ISS) |
|
N-terminal protein N-methyltransferase activity GO:0071885
Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to the alpha-amino group of the N-terminal amino or imino acid residue of a protein substrate. For example, yeast Tae1p and mammalian family member METTL11A preferentially modify the N-terminal residue of substrates with the N-terminal sequence X-Pro-Lys, where X can be Pro, Ala, or Ser.
|
8 | P38340 (/IMP) P38340 (/IMP) P38340 (/IMP) P38340 (/IMP) P38340 (/IMP) P38340 (/IMP) P38340 (/IMP) P38340 (/IMP) |
|
Protein methyltransferase activity GO:0008276
Catalysis of the transfer of a methyl group (CH3-) to a protein.
|
1 | Q8R2U4 (/ISO) |
|
Histone methyltransferase activity GO:0042054
Catalysis of the reaction: S-adenosyl-L-methionine + histone = S-adenosyl-L-homocysteine + methyl-histone. Histone methylation generally occurs on either an arginine or lysine residue.
|
1 | Q8R2U4 (/ISO) |
|
N-terminal protein N-methyltransferase activity GO:0071885
Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to the alpha-amino group of the N-terminal amino or imino acid residue of a protein substrate. For example, yeast Tae1p and mammalian family member METTL11A preferentially modify the N-terminal residue of substrates with the N-terminal sequence X-Pro-Lys, where X can be Pro, Ala, or Ser.
|
1 | Q8R2U4 (/ISO) |
There are 27 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
N-terminal peptidyl-proline dimethylation GO:0018016
The methylation of the N-terminal proline of proteins to form the derivative N,N-dimethyl-L-proline.
|
22 |
P38340 (/IDA)
P38340 (/IDA)
P38340 (/IDA)
P38340 (/IDA)
P38340 (/IDA)
P38340 (/IDA)
P38340 (/IDA)
P38340 (/IDA)
Q6NN40 (/IDA)
Q6NN40 (/IDA)
(12 more) |
|
Histone methylation GO:0016571
The modification of histones by addition of methyl groups.
|
13 |
Q6NN40 (/IDA)
Q6NN40 (/IDA)
Q9BV86 (/IDA)
Q9BV86 (/IDA)
Q9BV86 (/IDA)
Q9BV86 (/IDA)
Q9BV86 (/IDA)
Q9BV86 (/IDA)
Q9BV86 (/IDA)
Q9BV86 (/IDA)
(3 more) |
|
Spindle organization GO:0007051
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spindle, the array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during DNA segregation and serves to move the duplicated chromosomes apart.
|
11 |
Q9BV86 (/IMP)
Q9BV86 (/IMP)
Q9BV86 (/IMP)
Q9BV86 (/IMP)
Q9BV86 (/IMP)
Q9BV86 (/IMP)
Q9BV86 (/IMP)
Q9BV86 (/IMP)
Q9BV86 (/IMP)
Q9BV86 (/IMP)
(1 more) |
|
Chromosome segregation GO:0007059
The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.
|
11 |
Q9BV86 (/IMP)
Q9BV86 (/IMP)
Q9BV86 (/IMP)
Q9BV86 (/IMP)
Q9BV86 (/IMP)
Q9BV86 (/IMP)
Q9BV86 (/IMP)
Q9BV86 (/IMP)
Q9BV86 (/IMP)
Q9BV86 (/IMP)
(1 more) |
|
N-terminal peptidyl-glycine methylation GO:0018013
The methylation of the N-terminal glycine of proteins to form the derivative N-methylglycine.
|
11 |
Q9BV86 (/IDA)
Q9BV86 (/IDA)
Q9BV86 (/IDA)
Q9BV86 (/IDA)
Q9BV86 (/IDA)
Q9BV86 (/IDA)
Q9BV86 (/IDA)
Q9BV86 (/IDA)
Q9BV86 (/IDA)
Q9BV86 (/IDA)
(1 more) |
|
N-terminal peptidyl-serine dimethylation GO:0035572
The dimethylation of the N-terminal serine of proteins to form the derivative N,N-dimethylserine.
|
11 |
Q9BV86 (/IDA)
Q9BV86 (/IDA)
Q9BV86 (/IDA)
Q9BV86 (/IDA)
Q9BV86 (/IDA)
Q9BV86 (/IDA)
Q9BV86 (/IDA)
Q9BV86 (/IDA)
Q9BV86 (/IDA)
Q9BV86 (/IDA)
(1 more) |
|
N-terminal peptidyl-serine trimethylation GO:0035573
The trimethylation of the N-terminal serine of proteins to form the derivative N,N,N-trimethylserine.
|
11 |
Q9BV86 (/IDA)
Q9BV86 (/IDA)
Q9BV86 (/IDA)
Q9BV86 (/IDA)
Q9BV86 (/IDA)
Q9BV86 (/IDA)
Q9BV86 (/IDA)
Q9BV86 (/IDA)
Q9BV86 (/IDA)
Q9BV86 (/IDA)
(1 more) |
|
Spindle organization GO:0007051
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spindle, the array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during DNA segregation and serves to move the duplicated chromosomes apart.
|
9 | B1H2P7 (/ISS) D2H163 (/ISS) Q2T9N3 (/ISS) Q4KL94 (/ISS) Q4KLE6 (/ISS) Q4KLE6 (/ISS) Q5BJX0 (/ISS) Q6NWX7 (/ISS) Q8R2U4 (/ISS) |
|
Chromosome segregation GO:0007059
The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.
|
9 | B1H2P7 (/ISS) D2H163 (/ISS) Q2T9N3 (/ISS) Q4KL94 (/ISS) Q4KLE6 (/ISS) Q4KLE6 (/ISS) Q5BJX0 (/ISS) Q6NWX7 (/ISS) Q8R2U4 (/ISS) |
|
Histone methylation GO:0016571
The modification of histones by addition of methyl groups.
|
9 | B1H2P7 (/ISS) D2H163 (/ISS) Q2T9N3 (/ISS) Q4KL94 (/ISS) Q4KLE6 (/ISS) Q4KLE6 (/ISS) Q5BJX0 (/ISS) Q6NWX7 (/ISS) Q8R2U4 (/ISS) |
|
N-terminal peptidyl-glycine methylation GO:0018013
The methylation of the N-terminal glycine of proteins to form the derivative N-methylglycine.
|
9 | B1H2P7 (/ISS) D2H163 (/ISS) Q2T9N3 (/ISS) Q4KL94 (/ISS) Q4KLE6 (/ISS) Q4KLE6 (/ISS) Q5BJX0 (/ISS) Q6NWX7 (/ISS) Q8R2U4 (/ISS) |
|
N-terminal peptidyl-serine dimethylation GO:0035572
The dimethylation of the N-terminal serine of proteins to form the derivative N,N-dimethylserine.
|
9 | B1H2P7 (/ISS) D2H163 (/ISS) Q2T9N3 (/ISS) Q4KL94 (/ISS) Q4KLE6 (/ISS) Q4KLE6 (/ISS) Q5BJX0 (/ISS) Q6NWX7 (/ISS) Q8R2U4 (/ISS) |
|
N-terminal peptidyl-serine trimethylation GO:0035573
The trimethylation of the N-terminal serine of proteins to form the derivative N,N,N-trimethylserine.
|
9 | B1H2P7 (/ISS) D2H163 (/ISS) Q2T9N3 (/ISS) Q4KL94 (/ISS) Q4KLE6 (/ISS) Q4KLE6 (/ISS) Q5BJX0 (/ISS) Q6NWX7 (/ISS) Q8R2U4 (/ISS) |
|
Cytoplasmic translation GO:0002181
The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein.
|
8 | P38340 (/IGI) P38340 (/IGI) P38340 (/IGI) P38340 (/IGI) P38340 (/IGI) P38340 (/IGI) P38340 (/IGI) P38340 (/IGI) |
|
Cytoplasmic translation GO:0002181
The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein.
|
8 | P38340 (/IMP) P38340 (/IMP) P38340 (/IMP) P38340 (/IMP) P38340 (/IMP) P38340 (/IMP) P38340 (/IMP) P38340 (/IMP) |
|
N-terminal peptidyl-proline dimethylation GO:0018016
The methylation of the N-terminal proline of proteins to form the derivative N,N-dimethyl-L-proline.
|
8 | P38340 (/IMP) P38340 (/IMP) P38340 (/IMP) P38340 (/IMP) P38340 (/IMP) P38340 (/IMP) P38340 (/IMP) P38340 (/IMP) |
|
N-terminal peptidyl-proline dimethylation GO:0018016
The methylation of the N-terminal proline of proteins to form the derivative N,N-dimethyl-L-proline.
|
8 | B1H2P7 (/ISS) D2H163 (/ISS) Q2T9N3 (/ISS) Q4KL94 (/ISS) Q4KLE6 (/ISS) Q4KLE6 (/ISS) Q5BJX0 (/ISS) Q6NWX7 (/ISS) |
|
N-terminal peptidyl-proline methylation GO:0035568
The methylation of the N-terminal proline of proteins.
|
2 | Q6NN40 (/IDA) Q6NN40 (/IDA) |
|
Single-species biofilm formation on inanimate substrate GO:0044011
A process in which microorganisms of the same species attach to and grow on an inanimate surface such as a rock or pipe, and produce extracellular polymers that facilitate attachment and matrix formation, resulting in an alteration in the phenotype of the organisms with respect to growth rate and gene transcription.
|
2 | A0A1D8PQL1 (/IMP) A0A1D8PQL1 (/IMP) |
|
Spindle organization GO:0007051
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spindle, the array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during DNA segregation and serves to move the duplicated chromosomes apart.
|
1 | Q8R2U4 (/ISO) |
|
Chromosome segregation GO:0007059
The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.
|
1 | Q8R2U4 (/ISO) |
|
Histone methylation GO:0016571
The modification of histones by addition of methyl groups.
|
1 | Q8R2U4 (/ISO) |
|
N-terminal peptidyl-alanine trimethylation GO:0018012
The trimethylation of the N-terminal alanine of proteins to form the derivative peptidyl-N,N,N-trimethyl-L-alanine.
|
1 | Q8R2U4 (/IDA) |
|
N-terminal peptidyl-glycine methylation GO:0018013
The methylation of the N-terminal glycine of proteins to form the derivative N-methylglycine.
|
1 | Q8R2U4 (/ISO) |
|
N-terminal peptidyl-proline dimethylation GO:0018016
The methylation of the N-terminal proline of proteins to form the derivative N,N-dimethyl-L-proline.
|
1 | Q8R2U4 (/ISO) |
|
N-terminal peptidyl-serine dimethylation GO:0035572
The dimethylation of the N-terminal serine of proteins to form the derivative N,N-dimethylserine.
|
1 | Q8R2U4 (/ISO) |
|
N-terminal peptidyl-serine trimethylation GO:0035573
The trimethylation of the N-terminal serine of proteins to form the derivative N,N,N-trimethylserine.
|
1 | Q8R2U4 (/ISO) |
There are 8 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
30 |
A0A024R8E4 (/IDA)
A0A024R8E4 (/IDA)
A0A024R8E4 (/IDA)
A0A024R8E4 (/IDA)
A0A024R8E4 (/IDA)
A0A024R8E4 (/IDA)
A0A024R8E4 (/IDA)
A0A024R8E4 (/IDA)
A0A024R8E4 (/IDA)
A0A024R8E4 (/IDA)
(20 more) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
22 |
A0A024R8E4 (/IDA)
A0A024R8E4 (/IDA)
A0A024R8E4 (/IDA)
A0A024R8E4 (/IDA)
A0A024R8E4 (/IDA)
A0A024R8E4 (/IDA)
A0A024R8E4 (/IDA)
A0A024R8E4 (/IDA)
A0A024R8E4 (/IDA)
A0A024R8E4 (/IDA)
(12 more) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
13 |
Q6NN40 (/IDA)
Q6NN40 (/IDA)
Q9BV86 (/IDA)
Q9BV86 (/IDA)
Q9BV86 (/IDA)
Q9BV86 (/IDA)
Q9BV86 (/IDA)
Q9BV86 (/IDA)
Q9BV86 (/IDA)
Q9BV86 (/IDA)
(3 more) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
9 | B1H2P7 (/ISS) D2H163 (/ISS) Q2T9N3 (/ISS) Q4KL94 (/ISS) Q4KLE6 (/ISS) Q4KLE6 (/ISS) Q5BJX0 (/ISS) Q6NWX7 (/ISS) Q8R2U4 (/ISS) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
8 | P38340 (/HDA) P38340 (/HDA) P38340 (/HDA) P38340 (/HDA) P38340 (/HDA) P38340 (/HDA) P38340 (/HDA) P38340 (/HDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q8R2U4 (/ISO) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | Q8R2U4 (/ISO) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q8R2U4 (/ISO) |