The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
RNA polymerase II accessory factor, Cdc73 C-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Cell division cycle 73

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
72 Q6P1J9 (/IPI) Q6P1J9 (/IPI) Q6P1J9 (/IPI) Q6P1J9 (/IPI) Q6P1J9 (/IPI) Q6P1J9 (/IPI) Q6P1J9 (/IPI) Q6P1J9 (/IPI) Q6P1J9 (/IPI) Q6P1J9 (/IPI)
(62 more)
RNA polymerase II complex binding GO:0000993
Interacting selectively and non-covalently with RNA polymerase II core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of twelve subunits.
41 Q4V8C8 (/ISS) Q5ZLM0 (/ISS) Q5ZLM0 (/ISS) Q5ZLM0 (/ISS) Q5ZLM0 (/ISS) Q8JZM7 (/ISS) Q8JZM7 (/ISS) Q8JZM7 (/ISS) Q8JZM7 (/ISS) Q8JZM7 (/ISS)
(31 more)
RNA polymerase II complex binding GO:0000993
Interacting selectively and non-covalently with RNA polymerase II core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of twelve subunits.
36 Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA)
(26 more)
RNA polymerase II complex binding GO:0000993
Interacting selectively and non-covalently with RNA polymerase II core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of twelve subunits.
36 Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO)
(26 more)

There are 57 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
72 Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP)
(62 more)
Endodermal cell fate commitment GO:0001711
The cell differentiation process that results in commitment of a cell to become part of the endoderm.
41 Q4V8C8 (/ISS) Q5ZLM0 (/ISS) Q5ZLM0 (/ISS) Q5ZLM0 (/ISS) Q5ZLM0 (/ISS) Q6P1J9 (/ISS) Q6P1J9 (/ISS) Q6P1J9 (/ISS) Q6P1J9 (/ISS) Q6P1J9 (/ISS)
(31 more)
MRNA polyadenylation GO:0006378
The enzymatic addition of a sequence of 40-200 adenylyl residues at the 3' end of a eukaryotic mRNA primary transcript.
41 Q4V8C8 (/ISS) Q5ZLM0 (/ISS) Q5ZLM0 (/ISS) Q5ZLM0 (/ISS) Q5ZLM0 (/ISS) Q8JZM7 (/ISS) Q8JZM7 (/ISS) Q8JZM7 (/ISS) Q8JZM7 (/ISS) Q8JZM7 (/ISS)
(31 more)
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
41 Q4V8C8 (/ISS) Q5ZLM0 (/ISS) Q5ZLM0 (/ISS) Q5ZLM0 (/ISS) Q5ZLM0 (/ISS) Q8JZM7 (/ISS) Q8JZM7 (/ISS) Q8JZM7 (/ISS) Q8JZM7 (/ISS) Q8JZM7 (/ISS)
(31 more)
Stem cell population maintenance GO:0019827
The process by which an organism or tissue maintains a population of stem cells of a single type. This can be achieved by a number of mechanisms: stem cell asymmetric division maintains stem cell numbers; stem cell symmetric division increases them; maintenance of a stem cell niche maintains the conditions for commitment to the stem cell fate for some types of stem cell; stem cells may arise de novo from other cell types.
41 Q4V8C8 (/ISS) Q5ZLM0 (/ISS) Q5ZLM0 (/ISS) Q5ZLM0 (/ISS) Q5ZLM0 (/ISS) Q6P1J9 (/ISS) Q6P1J9 (/ISS) Q6P1J9 (/ISS) Q6P1J9 (/ISS) Q6P1J9 (/ISS)
(31 more)
Positive regulation of Wnt signaling pathway GO:0030177
Any process that activates or increases the frequency, rate or extent of Wnt signal transduction.
41 Q4V8C8 (/ISS) Q5ZLM0 (/ISS) Q5ZLM0 (/ISS) Q5ZLM0 (/ISS) Q5ZLM0 (/ISS) Q8JZM7 (/ISS) Q8JZM7 (/ISS) Q8JZM7 (/ISS) Q8JZM7 (/ISS) Q8JZM7 (/ISS)
(31 more)
Positive regulation of mRNA 3'-end processing GO:0031442
Any process that activates or increases the frequency, rate or extent of mRNA 3'-end processing.
41 Q4V8C8 (/ISS) Q5ZLM0 (/ISS) Q5ZLM0 (/ISS) Q5ZLM0 (/ISS) Q5ZLM0 (/ISS) Q8JZM7 (/ISS) Q8JZM7 (/ISS) Q8JZM7 (/ISS) Q8JZM7 (/ISS) Q8JZM7 (/ISS)
(31 more)
Positive regulation of transcription elongation from RNA polymerase II promoter GO:0032968
Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.
41 Q4V8C8 (/ISS) Q5ZLM0 (/ISS) Q5ZLM0 (/ISS) Q5ZLM0 (/ISS) Q5ZLM0 (/ISS) Q8JZM7 (/ISS) Q8JZM7 (/ISS) Q8JZM7 (/ISS) Q8JZM7 (/ISS) Q8JZM7 (/ISS)
(31 more)
Negative regulation of myeloid cell differentiation GO:0045638
Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid cell differentiation.
41 Q4V8C8 (/ISS) Q5ZLM0 (/ISS) Q5ZLM0 (/ISS) Q5ZLM0 (/ISS) Q5ZLM0 (/ISS) Q8JZM7 (/ISS) Q8JZM7 (/ISS) Q8JZM7 (/ISS) Q8JZM7 (/ISS) Q8JZM7 (/ISS)
(31 more)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
41 Q4V8C8 (/ISS) Q5ZLM0 (/ISS) Q5ZLM0 (/ISS) Q5ZLM0 (/ISS) Q5ZLM0 (/ISS) Q8JZM7 (/ISS) Q8JZM7 (/ISS) Q8JZM7 (/ISS) Q8JZM7 (/ISS) Q8JZM7 (/ISS)
(31 more)
Positive regulation of cell cycle G1/S phase transition GO:1902808
Any signalling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the cell cycle.
41 Q4V8C8 (/ISS) Q5ZLM0 (/ISS) Q5ZLM0 (/ISS) Q5ZLM0 (/ISS) Q5ZLM0 (/ISS) Q8JZM7 (/ISS) Q8JZM7 (/ISS) Q8JZM7 (/ISS) Q8JZM7 (/ISS) Q8JZM7 (/ISS)
(31 more)
Negative regulation of G1/S transition of mitotic cell cycle GO:2000134
Any signalling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the mitotic cell cycle.
41 Q4V8C8 (/ISS) Q5ZLM0 (/ISS) Q5ZLM0 (/ISS) Q5ZLM0 (/ISS) Q5ZLM0 (/ISS) Q8JZM7 (/ISS) Q8JZM7 (/ISS) Q8JZM7 (/ISS) Q8JZM7 (/ISS) Q8JZM7 (/ISS)
(31 more)
Cellular response to lipopolysaccharide GO:0071222
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
37 Q4V8C8 (/ISS) Q6P1J9 (/ISS) Q6P1J9 (/ISS) Q6P1J9 (/ISS) Q6P1J9 (/ISS) Q6P1J9 (/ISS) Q6P1J9 (/ISS) Q6P1J9 (/ISS) Q6P1J9 (/ISS) Q6P1J9 (/ISS)
(27 more)
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
36 Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO)
(26 more)
Regulation of cell growth GO:0001558
Any process that modulates the frequency, rate, extent or direction of cell growth.
36 Q8JZM7 (/IMP) Q8JZM7 (/IMP) Q8JZM7 (/IMP) Q8JZM7 (/IMP) Q8JZM7 (/IMP) Q8JZM7 (/IMP) Q8JZM7 (/IMP) Q8JZM7 (/IMP) Q8JZM7 (/IMP) Q8JZM7 (/IMP)
(26 more)
Endodermal cell fate commitment GO:0001711
The cell differentiation process that results in commitment of a cell to become part of the endoderm.
36 Q8JZM7 (/IMP) Q8JZM7 (/IMP) Q8JZM7 (/IMP) Q8JZM7 (/IMP) Q8JZM7 (/IMP) Q8JZM7 (/IMP) Q8JZM7 (/IMP) Q8JZM7 (/IMP) Q8JZM7 (/IMP) Q8JZM7 (/IMP)
(26 more)
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
36 Q8JZM7 (/IMP) Q8JZM7 (/IMP) Q8JZM7 (/IMP) Q8JZM7 (/IMP) Q8JZM7 (/IMP) Q8JZM7 (/IMP) Q8JZM7 (/IMP) Q8JZM7 (/IMP) Q8JZM7 (/IMP) Q8JZM7 (/IMP)
(26 more)
Transcription by RNA polymerase II GO:0006366
The synthesis of RNA from a DNA template by RNA polymerase II (RNAP II), originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs).
36 Q6P1J9 (/TAS) Q6P1J9 (/TAS) Q6P1J9 (/TAS) Q6P1J9 (/TAS) Q6P1J9 (/TAS) Q6P1J9 (/TAS) Q6P1J9 (/TAS) Q6P1J9 (/TAS) Q6P1J9 (/TAS) Q6P1J9 (/TAS)
(26 more)
Transcription elongation from RNA polymerase II promoter GO:0006368
The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase II promoter by the addition of ribonucleotides catalyzed by RNA polymerase II.
36 Q6P1J9 (/TAS) Q6P1J9 (/TAS) Q6P1J9 (/TAS) Q6P1J9 (/TAS) Q6P1J9 (/TAS) Q6P1J9 (/TAS) Q6P1J9 (/TAS) Q6P1J9 (/TAS) Q6P1J9 (/TAS) Q6P1J9 (/TAS)
(26 more)
MRNA polyadenylation GO:0006378
The enzymatic addition of a sequence of 40-200 adenylyl residues at the 3' end of a eukaryotic mRNA primary transcript.
36 Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP)
(26 more)
MRNA polyadenylation GO:0006378
The enzymatic addition of a sequence of 40-200 adenylyl residues at the 3' end of a eukaryotic mRNA primary transcript.
36 Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO)
(26 more)
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
36 Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA)
(26 more)
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
36 Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO)
(26 more)
Histone monoubiquitination GO:0010390
The modification of histones by addition of a single ubiquitin group.
36 Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA)
(26 more)
Histone monoubiquitination GO:0010390
The modification of histones by addition of a single ubiquitin group.
36 Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO)
(26 more)
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
36 Q6P1J9 (/TAS) Q6P1J9 (/TAS) Q6P1J9 (/TAS) Q6P1J9 (/TAS) Q6P1J9 (/TAS) Q6P1J9 (/TAS) Q6P1J9 (/TAS) Q6P1J9 (/TAS) Q6P1J9 (/TAS) Q6P1J9 (/TAS)
(26 more)
Stem cell population maintenance GO:0019827
The process by which an organism or tissue maintains a population of stem cells of a single type. This can be achieved by a number of mechanisms: stem cell asymmetric division maintains stem cell numbers; stem cell symmetric division increases them; maintenance of a stem cell niche maintains the conditions for commitment to the stem cell fate for some types of stem cell; stem cells may arise de novo from other cell types.
36 Q8JZM7 (/IMP) Q8JZM7 (/IMP) Q8JZM7 (/IMP) Q8JZM7 (/IMP) Q8JZM7 (/IMP) Q8JZM7 (/IMP) Q8JZM7 (/IMP) Q8JZM7 (/IMP) Q8JZM7 (/IMP) Q8JZM7 (/IMP)
(26 more)
Positive regulation of Wnt signaling pathway GO:0030177
Any process that activates or increases the frequency, rate or extent of Wnt signal transduction.
36 Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA)
(26 more)
Positive regulation of Wnt signaling pathway GO:0030177
Any process that activates or increases the frequency, rate or extent of Wnt signal transduction.
36 Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO)
(26 more)
Positive regulation of mRNA 3'-end processing GO:0031442
Any process that activates or increases the frequency, rate or extent of mRNA 3'-end processing.
36 Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP)
(26 more)
Positive regulation of mRNA 3'-end processing GO:0031442
Any process that activates or increases the frequency, rate or extent of mRNA 3'-end processing.
36 Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO)
(26 more)
Protein destabilization GO:0031648
Any process that decreases the stability of a protein, making it more vulnerable to degradative processes or aggregation.
36 Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP)
(26 more)
Protein destabilization GO:0031648
Any process that decreases the stability of a protein, making it more vulnerable to degradative processes or aggregation.
36 Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO)
(26 more)
Positive regulation of transcription elongation from RNA polymerase II promoter GO:0032968
Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.
36 Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA)
(26 more)
Positive regulation of transcription elongation from RNA polymerase II promoter GO:0032968
Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.
36 Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO)
(26 more)
Histone H2B ubiquitination GO:0033523
The modification of histone H2B by addition of ubiquitin groups.
36 Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA)
(26 more)
Histone H2B ubiquitination GO:0033523
The modification of histone H2B by addition of ubiquitin groups.
36 Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO)
(26 more)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
36 Q8JZM7 (/IMP) Q8JZM7 (/IMP) Q8JZM7 (/IMP) Q8JZM7 (/IMP) Q8JZM7 (/IMP) Q8JZM7 (/IMP) Q8JZM7 (/IMP) Q8JZM7 (/IMP) Q8JZM7 (/IMP) Q8JZM7 (/IMP)
(26 more)
Negative regulation of myeloid cell differentiation GO:0045638
Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid cell differentiation.
36 Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA)
(26 more)
Negative regulation of myeloid cell differentiation GO:0045638
Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid cell differentiation.
36 Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO)
(26 more)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
36 Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA)
(26 more)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
36 Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO)
(26 more)
Negative regulation of fibroblast proliferation GO:0048147
Any process that stops, prevents, or reduces the frequency, rate or extent of multiplication or reproduction of fibroblast cells.
36 Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP)
(26 more)
Negative regulation of fibroblast proliferation GO:0048147
Any process that stops, prevents, or reduces the frequency, rate or extent of multiplication or reproduction of fibroblast cells.
36 Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO)
(26 more)
Negative regulation of epithelial cell proliferation GO:0050680
Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation.
36 Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP)
(26 more)
Negative regulation of epithelial cell proliferation GO:0050680
Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation.
36 Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO)
(26 more)
Cellular response to lipopolysaccharide GO:0071222
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
36 Q8JZM7 (/IDA) Q8JZM7 (/IDA) Q8JZM7 (/IDA) Q8JZM7 (/IDA) Q8JZM7 (/IDA) Q8JZM7 (/IDA) Q8JZM7 (/IDA) Q8JZM7 (/IDA) Q8JZM7 (/IDA) Q8JZM7 (/IDA)
(26 more)
Positive regulation of cell cycle G1/S phase transition GO:1902808
Any signalling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the cell cycle.
36 Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP) Q6P1J9 (/IMP)
(26 more)
Positive regulation of cell cycle G1/S phase transition GO:1902808
Any signalling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the cell cycle.
36 Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO)
(26 more)
Beta-catenin-TCF complex assembly GO:1904837
The aggregation, arrangement and bonding together of a set of components to form a beta-catenin-TCF complex.
36 Q6P1J9 (/TAS) Q6P1J9 (/TAS) Q6P1J9 (/TAS) Q6P1J9 (/TAS) Q6P1J9 (/TAS) Q6P1J9 (/TAS) Q6P1J9 (/TAS) Q6P1J9 (/TAS) Q6P1J9 (/TAS) Q6P1J9 (/TAS)
(26 more)
Negative regulation of G1/S transition of mitotic cell cycle GO:2000134
Any signalling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the mitotic cell cycle.
36 Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA)
(26 more)
Negative regulation of G1/S transition of mitotic cell cycle GO:2000134
Any signalling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the mitotic cell cycle.
36 Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO)
(26 more)
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
5 Q4V8C8 (/ISS) Q5ZLM0 (/ISS) Q5ZLM0 (/ISS) Q5ZLM0 (/ISS) Q5ZLM0 (/ISS)
Spinal cord oligodendrocyte cell differentiation GO:0021529
The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of oligodendrocytes. Oligodendrocytes are non-neuronal cells. The primary function of oligodendrocytes is the myelination of nerve axons in the central nervous system. Differentiation includes the processes involved in commitment of a cell to a specific fate.
2 Q7T3D4 (/IMP) X1WHN7 (/IMP)
Erythrocyte differentiation GO:0030218
The process in which a myeloid precursor cell acquires specializes features of an erythrocyte.
2 Q7T3D4 (/IGI) X1WHN7 (/IGI)
Regulation of transcription elongation from RNA polymerase II promoter GO:0034243
Any process that modulates the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.
2 Q7T3D4 (/IGI) X1WHN7 (/IGI)
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
1 Q7T3D4 (/IMP)

There are 10 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
51 A0A1B0GUB2 (/IDA) A0A1B0GUB2 (/IDA) A0A1B0GUB2 (/IDA) A0A1B0GUB2 (/IDA) A0A1B0GUB2 (/IDA) A0A1B0GUB2 (/IDA) A0A1B0GUB2 (/IDA) A0A1B0GUB2 (/IDA) A0A1B0GUB2 (/IDA) A0A1B0GUB2 (/IDA)
(41 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
49 A0A1B0GUB2 (/IDA) A0A1B0GUB2 (/IDA) A0A1B0GUB2 (/IDA) A0A1B0GUB2 (/IDA) A0A1B0GUB2 (/IDA) A0A1B0GUB2 (/IDA) A0A1B0GUB2 (/IDA) A0A1B0GUB2 (/IDA) A0A1B0GUB2 (/IDA) A0A1B0GUB2 (/IDA)
(39 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
41 Q4V8C8 (/ISS) Q5ZLM0 (/ISS) Q5ZLM0 (/ISS) Q5ZLM0 (/ISS) Q5ZLM0 (/ISS) Q8JZM7 (/ISS) Q8JZM7 (/ISS) Q8JZM7 (/ISS) Q8JZM7 (/ISS) Q8JZM7 (/ISS)
(31 more)
Cdc73/Paf1 complex GO:0016593
A multiprotein complex that associates with RNA polymerase II and general RNA polymerase II transcription factor complexes and may be involved in both transcriptional initiation and elongation. In Saccharomyces the complex contains Paf1p, Cdc73p, Ctr9p, Rtf1p, and Leo1p.
41 Q4V8C8 (/ISS) Q5ZLM0 (/ISS) Q5ZLM0 (/ISS) Q5ZLM0 (/ISS) Q5ZLM0 (/ISS) Q8JZM7 (/ISS) Q8JZM7 (/ISS) Q8JZM7 (/ISS) Q8JZM7 (/ISS) Q8JZM7 (/ISS)
(31 more)
Cdc73/Paf1 complex GO:0016593
A multiprotein complex that associates with RNA polymerase II and general RNA polymerase II transcription factor complexes and may be involved in both transcriptional initiation and elongation. In Saccharomyces the complex contains Paf1p, Cdc73p, Ctr9p, Rtf1p, and Leo1p.
38 Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA) Q6P1J9 (/IDA)
(28 more)
Nuclear chromosome, telomeric region GO:0000784
The terminal region of a linear nuclear chromosome that includes the telomeric DNA repeats and associated proteins.
36 Q6P1J9 (/HDA) Q6P1J9 (/HDA) Q6P1J9 (/HDA) Q6P1J9 (/HDA) Q6P1J9 (/HDA) Q6P1J9 (/HDA) Q6P1J9 (/HDA) Q6P1J9 (/HDA) Q6P1J9 (/HDA) Q6P1J9 (/HDA)
(26 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
36 Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO)
(26 more)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
36 Q6P1J9 (/TAS) Q6P1J9 (/TAS) Q6P1J9 (/TAS) Q6P1J9 (/TAS) Q6P1J9 (/TAS) Q6P1J9 (/TAS) Q6P1J9 (/TAS) Q6P1J9 (/TAS) Q6P1J9 (/TAS) Q6P1J9 (/TAS)
(26 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
36 Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO)
(26 more)
Cdc73/Paf1 complex GO:0016593
A multiprotein complex that associates with RNA polymerase II and general RNA polymerase II transcription factor complexes and may be involved in both transcriptional initiation and elongation. In Saccharomyces the complex contains Paf1p, Cdc73p, Ctr9p, Rtf1p, and Leo1p.
36 Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO) Q8JZM7 (/ISO)
(26 more)