The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Nucleotide cyclase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 22: Receptor-type adenylate cyclase GRESAG 4, putative

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Adenylate cyclase activity GO:0004016
Catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate.
49 Q382G3 (/ISM) Q382G3 (/ISM) Q385H4 (/ISM) Q387A4 (/ISM) Q387N6 (/ISM) Q387P6 (/ISM) Q387R5 (/ISM) Q388U2 (/ISM) Q38C02 (/ISM) Q38CU7 (/ISM)
(39 more)
Adenylate cyclase activity GO:0004016
Catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate.
9 D6XEJ9 (/IDA) D6XEJ9 (/IDA) Q581G5 (/IDA) Q581G5 (/IDA) Q583C8 (/IDA) Q583C9 (/IDA) Q583D0 (/IDA) Q583D1 (/IDA) Q583D2 (/IDA)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
9 D6XEJ9 (/IDA) D6XEJ9 (/IDA) Q581G5 (/IDA) Q581G5 (/IDA) Q583C8 (/IDA) Q583C9 (/IDA) Q583D0 (/IDA) Q583D1 (/IDA) Q583D2 (/IDA)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
5 Q382G3 (/ISO) Q382G3 (/ISO) Q388U2 (/ISO) Q38CU7 (/ISO) Q57TY4 (/ISO)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
2 Q380Y3 (/IDA) Q387P6 (/IDA)

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Intracellular signal transduction GO:0035556
The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
58 D6XEJ9 (/ISM) D6XEJ9 (/ISM) Q382G3 (/ISM) Q382G3 (/ISM) Q385H4 (/ISM) Q387A4 (/ISM) Q387N6 (/ISM) Q387P6 (/ISM) Q387R5 (/ISM) Q388U2 (/ISM)
(48 more)
CAMP-mediated signaling GO:0019933
Any intracellular signal transduction in which the signal is passed on within the cell via cyclic AMP (cAMP). Includes production of cAMP, and downstream effectors that further transmit the signal within the cell.
1 Q380Y3 (/TAS)

There are 7 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cilium GO:0005929
A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body.
8 Q380Y3 (/IDA) Q382G3 (/IDA) Q382G3 (/IDA) Q387P6 (/IDA) Q388U2 (/IDA) Q57Z02 (/IDA) Q57Z02 (/IDA) Q57Z02 (/IDA)
Ciliary transition zone GO:0035869
A region of the cilium between the basal body and proximal segment that is characterized by Y-shaped assemblages that connect axonemal microtubules to the ciliary membrane. The ciliary transition zone appears to function as a gate that controls ciliary membrane composition and separates the cytosol from the ciliary plasm.
3 Q57Z02 (/IDA) Q57Z02 (/IDA) Q57Z02 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q387N6 (/IDA) Q583I0 (/IDA)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
2 Q38CU7 (/ISA) Q57WZ9 (/ISA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q387R5 (/RCA)
Cilium GO:0005929
A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body.
1 Q4QJJ8 (/ISO)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 Q380Y3 (/IDA)