The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Histidine kinase-like ATPase, C-terminal domain
".
FunFam 15: Two-component osmosensing histidine kinase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Phosphorelay sensor kinase activity GO:0000155
Catalysis of the phosphorylation of a histidine residue in response to detection of an extracellular signal such as a chemical ligand or change in environment, to initiate a change in cell state or activity. The two-component sensor is a histidine kinase that autophosphorylates a histidine residue in its active site. The phosphate is then transferred to an aspartate residue in a downstream response regulator, to trigger a response.
|
3 | Q5A599 (/ISS) Q5A599 (/ISS) Q5A599 (/ISS) |
|
Phosphorelay response regulator activity GO:0000156
Responds to a phosphorelay sensor to initiate a change in cell state or activity. The activity of the response regulator is regulated by transfer of a phosphate from a histidine residue in the sensor, to an aspartate residue in the response regulator. Many but not all response regulators act as transcriptional regulators to elicit a response.
|
3 | Q5A599 (/ISS) Q5A599 (/ISS) Q5A599 (/ISS) |
|
Protein histidine kinase activity GO:0004673
Catalysis of the reaction: ATP + protein L-histidine = ADP + protein phospho-L-histidine.
|
3 | Q5A599 (/IDA) Q5A599 (/IDA) Q5A599 (/IDA) |
|
Protein histidine kinase activity GO:0004673
Catalysis of the reaction: ATP + protein L-histidine = ADP + protein phospho-L-histidine.
|
3 | Q5A599 (/ISS) Q5A599 (/ISS) Q5A599 (/ISS) |
There are 12 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cellular response to farnesol GO:0097308
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a farnesol stimulus.
|
6 | Q4WI04 (/IMP) Q4WI04 (/IMP) Q4WI04 (/IMP) Q5A599 (/IMP) Q5A599 (/IMP) Q5A599 (/IMP) |
|
Osmosensory signaling via phosphorelay pathway GO:0007234
A series of molecular signals generated in response to osmotic change, as mediated through a phosphorelay system.
|
3 | Q5A599 (/ISS) Q5A599 (/ISS) Q5A599 (/ISS) |
|
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
|
3 | Q5A599 (/IMP) Q5A599 (/IMP) Q5A599 (/IMP) |
|
Filamentous growth GO:0030447
The process in which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.
|
3 | Q5A599 (/IMP) Q5A599 (/IMP) Q5A599 (/IMP) |
|
Filamentous growth of a population of unicellular organisms in response to starvation GO:0036170
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to deprivation of nourishment.
|
3 | Q5A599 (/IMP) Q5A599 (/IMP) Q5A599 (/IMP) |
|
Filamentous growth of a population of unicellular organisms in response to biotic stimulus GO:0036180
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a biotic (living) stimulus.
|
3 | Q5A599 (/IMP) Q5A599 (/IMP) Q5A599 (/IMP) |
|
Cellular response to osmotic stress GO:0071470
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
|
3 | Q4WI04 (/ISO) Q4WI04 (/ISO) Q4WI04 (/ISO) |
|
Cellular response to cation stress GO:0071473
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cation stress, an increase or decrease in the concentration of positively charged ions in the environment.
|
3 | Q4WI04 (/IMP) Q4WI04 (/IMP) Q4WI04 (/IMP) |
|
Positive regulation of filamentous growth of a population of unicellular organisms in response to starvation GO:1900436
Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to starvation.
|
3 | Q5A599 (/IMP) Q5A599 (/IMP) Q5A599 (/IMP) |
|
Positive regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus GO:1900445
Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to biotic stimulus.
|
3 | Q5A599 (/IMP) Q5A599 (/IMP) Q5A599 (/IMP) |
|
Cellular response to osmotic stress GO:0071470
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
|
1 | C8V8F5 (/IMP) |
|
Cellular hyperosmotic response GO:0071474
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hyperosmotic environment, i.e. an environment with a higher concentration of solutes than the organism or cell.
|
1 | C8V8F5 (/IMP) |
There are 0 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.