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CATH Superfamily 3.20.20.70

Aldolase class I

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Aldolase class I
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 32: Homocitrate synthase, mitochondrial

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Homocitrate synthase. [EC: 2.3.3.14]
Acetyl-CoA + H(2)O + 2-oxoglutarate = (R)-2-hydroxybutane-1,2,4- tricarboxylate + CoA.
  • Belongs in the alpha-aminoadipate pathway of lysine synthesis, along with EC 4.2.1.36.
  • Also acts with oxaloacetate as substrate, but more slowly.
  • Formerly EC 4.1.3.21.
 78 A0A0L8VSB0 A0A0L8VSB0 A0A0L8VSB0 A0A0L8VSB0 A0A0L8VSB0 A0A0L8VSB0 A0A0L8VSG9 A0A0L8VSG9 A0A0L8VSG9 A0A0L8VSG9
(68 more...)