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CATH Superfamily 3.20.20.100

NADP-dependent oxidoreductase domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
NADP-dependent oxidoreductase domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 30: Aldo-keto reductase family 1 member E2

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
1,5-anhydro-D-fructose reductase. [EC: 1.1.1.263]
1,5-anhydro-D-glucitol + NADP(+) = 1,5-anhydro-D-fructose + NADPH.
  • Also reduces pyridine-3-aldehyde and 2,3-butanedione.
  • Acetaldehyde, 2-dehydroglucose (glucosone) and glucuronate are poor substrates, but there is no detectable action on glucose, mannose and fructose.
 8 A0A480M8G9 A0A480M8G9 P82125 P82125 Q4R802 Q5U1Y4 Q96JD6 Q9DCT1