The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Ubiquitin Conjugating Enzyme
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 42: Ubiquitin-fold modifier-conjugating enzyme 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
17 Q9Y3C8 (/IPI) Q9Y3C8 (/IPI) Q9Y3C8 (/IPI) Q9Y3C8 (/IPI) Q9Y3C8 (/IPI) Q9Y3C8 (/IPI) Q9Y3C8 (/IPI) Q9Y3C8 (/IPI) Q9Y3C8 (/IPI) Q9Y3C8 (/IPI)
(7 more)
UFM1 transferase activity GO:0071568
Catalysis of the transfer of UFM1 from one protein to another via the reaction X-UFM1 + Y --> Y-UFM1 + X, where both X-UFM1 and Y-UFM1 are covalent linkages.
17 Q9Y3C8 (/IDA) Q9Y3C8 (/IDA) Q9Y3C8 (/IDA) Q9Y3C8 (/IDA) Q9Y3C8 (/IDA) Q9Y3C8 (/IDA) Q9Y3C8 (/IDA) Q9Y3C8 (/IDA) Q9Y3C8 (/IDA) Q9Y3C8 (/IDA)
(7 more)
UFM1 transferase activity GO:0071568
Catalysis of the transfer of UFM1 from one protein to another via the reaction X-UFM1 + Y --> Y-UFM1 + X, where both X-UFM1 and Y-UFM1 are covalent linkages.
16 B9EM04 (/ISS) C1BKD1 (/ISS) C1BZU2 (/ISS) Q5E953 (/ISS) Q5E953 (/ISS) Q5E953 (/ISS) Q5E953 (/ISS) Q5E953 (/ISS) Q5E953 (/ISS) Q5E953 (/ISS)
(6 more)
Ubiquitin conjugating enzyme binding GO:0031624
Interacting selectively and non-covalently with a ubiquitin conjugating enzyme, any of the E2 proteins.
1 Q03598 (/IPI)
UFM1 transferase activity GO:0071568
Catalysis of the transfer of UFM1 from one protein to another via the reaction X-UFM1 + Y --> Y-UFM1 + X, where both X-UFM1 and Y-UFM1 are covalent linkages.
1 Q9CR09 (/ISO)

There are 12 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Brain development GO:0007420
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
17 Q9Y3C8 (/IMP) Q9Y3C8 (/IMP) Q9Y3C8 (/IMP) Q9Y3C8 (/IMP) Q9Y3C8 (/IMP) Q9Y3C8 (/IMP) Q9Y3C8 (/IMP) Q9Y3C8 (/IMP) Q9Y3C8 (/IMP) Q9Y3C8 (/IMP)
(7 more)
Response to endoplasmic reticulum stress GO:0034976
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stress acting at the endoplasmic reticulum. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.
17 Q9Y3C8 (/IDA) Q9Y3C8 (/IDA) Q9Y3C8 (/IDA) Q9Y3C8 (/IDA) Q9Y3C8 (/IDA) Q9Y3C8 (/IDA) Q9Y3C8 (/IDA) Q9Y3C8 (/IDA) Q9Y3C8 (/IDA) Q9Y3C8 (/IDA)
(7 more)
Protein ufmylation GO:0071569
Covalent attachment of the ubiquitin-like protein UFM1 to another protein.
17 Q9Y3C8 (/IDA) Q9Y3C8 (/IDA) Q9Y3C8 (/IDA) Q9Y3C8 (/IDA) Q9Y3C8 (/IDA) Q9Y3C8 (/IDA) Q9Y3C8 (/IDA) Q9Y3C8 (/IDA) Q9Y3C8 (/IDA) Q9Y3C8 (/IDA)
(7 more)
Protein ufmylation GO:0071569
Covalent attachment of the ubiquitin-like protein UFM1 to another protein.
17 Q9Y3C8 (/IMP) Q9Y3C8 (/IMP) Q9Y3C8 (/IMP) Q9Y3C8 (/IMP) Q9Y3C8 (/IMP) Q9Y3C8 (/IMP) Q9Y3C8 (/IMP) Q9Y3C8 (/IMP) Q9Y3C8 (/IMP) Q9Y3C8 (/IMP)
(7 more)
Protein K69-linked ufmylation GO:1990592
A protein ufmylation process in which a polymer of the ubiquitin-like protein UFM1 is formed by linkages between lysine residues at position 69 of the UFM1 monomers, is added to a protein.
17 Q9Y3C8 (/IDA) Q9Y3C8 (/IDA) Q9Y3C8 (/IDA) Q9Y3C8 (/IDA) Q9Y3C8 (/IDA) Q9Y3C8 (/IDA) Q9Y3C8 (/IDA) Q9Y3C8 (/IDA) Q9Y3C8 (/IDA) Q9Y3C8 (/IDA)
(7 more)
Protein ufmylation GO:0071569
Covalent attachment of the ubiquitin-like protein UFM1 to another protein.
16 B9EM04 (/ISS) C1BKD1 (/ISS) C1BZU2 (/ISS) Q5E953 (/ISS) Q5E953 (/ISS) Q5E953 (/ISS) Q5E953 (/ISS) Q5E953 (/ISS) Q5E953 (/ISS) Q5E953 (/ISS)
(6 more)
Protein K69-linked ufmylation GO:1990592
A protein ufmylation process in which a polymer of the ubiquitin-like protein UFM1 is formed by linkages between lysine residues at position 69 of the UFM1 monomers, is added to a protein.
12 Q5E953 (/ISS) Q5E953 (/ISS) Q5E953 (/ISS) Q5E953 (/ISS) Q5E953 (/ISS) Q5E953 (/ISS) Q5E953 (/ISS) Q5E953 (/ISS) Q5E953 (/ISS) Q5E953 (/ISS)
(2 more)
Brain development GO:0007420
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
11 Q5E953 (/ISS) Q5E953 (/ISS) Q5E953 (/ISS) Q5E953 (/ISS) Q5E953 (/ISS) Q5E953 (/ISS) Q5E953 (/ISS) Q5E953 (/ISS) Q5E953 (/ISS) Q5E953 (/ISS)
(1 more)
Brain development GO:0007420
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
1 Q9CR09 (/ISO)
Response to endoplasmic reticulum stress GO:0034976
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stress acting at the endoplasmic reticulum. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.
1 Q9CR09 (/ISO)
Protein ufmylation GO:0071569
Covalent attachment of the ubiquitin-like protein UFM1 to another protein.
1 Q9CR09 (/ISO)
Protein K69-linked ufmylation GO:1990592
A protein ufmylation process in which a polymer of the ubiquitin-like protein UFM1 is formed by linkages between lysine residues at position 69 of the UFM1 monomers, is added to a protein.
1 Q9CR09 (/ISO)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
17 Q9Y3C8 (/HDA) Q9Y3C8 (/HDA) Q9Y3C8 (/HDA) Q9Y3C8 (/HDA) Q9Y3C8 (/HDA) Q9Y3C8 (/HDA) Q9Y3C8 (/HDA) Q9Y3C8 (/HDA) Q9Y3C8 (/HDA) Q9Y3C8 (/HDA)
(7 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q03598 (/HDA)
Striated muscle dense body GO:0055120
A vinculin-containing myofibril attachment structure of striated muscle that connects sarcomeres to the extracellular matrix. In nematode body wall muscle, the dense body performs the dual role of Z-disk and costamere.
1 Q03598 (/HDA)