The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Ubiquitin Conjugating Enzyme
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
986
3D
4x57C00 - 81.9
2
821
3D
4gprA00 - 88.4
3
618
3D
3bzhA00 - 78.8
4
529
3D
1z3dA00 - 81.8
5
506
3D
3o2uB01 - 90.0
6
491
3D
1zuoB00 - 82.2
7
458
3D
4r62A00 - 69.1
8
437
3D
4ladA00 - 84.3
9
421
3D
4mdkD00 - 76.5
11
413
3D
6n13C00 - 92.3
10
407
3D
4ii2C00 - 73.0
12
380
3D
2hlwA01 - 80.7
15
380
3D
5vo0E00 - 91.5
13
378
3D
2vrrA00 - 78.4
14
331
3D
3cegB00 - 79.8
17
328
3D
2aakA00 - 54.7
16
328
3D
2onuA00 - 84.2
18
324
3D
2awfA00 - 70.9
19
291 - - 74.1
20
281
3D
4fh1A00 - 70.2
21
277
3D
6if1B01 - 86.9
22
262
3D
2mt6A00 - 71.3
23
245
3D
2f4wB00 - 87.7
24
232 - - 78.7
25
224
3D
5knlF00 - 83.2
26
220
3D
2gmiB00 - 85.2
27
196 - - 59.3
28
193 - - 85.4
29
191 - - 54.6
31
186 - - 87.9
30
186 - - 66.9
34
184
3D
5bnbC00 - 74.1
35
183
3D
3rczB00 - 90.5
33
183
3D
3fn1B00 - 93.7
32
182 - - 73.7
37
169
3D
1tteA01 - 88.1
36
165 - - 88.8
40
163
3D
5vkgA00 - 79.7
39
155
3D
4yiiU00 - 76.2
42
154
3D
3evxD00 - 76.5
41
152
3D
5ojjF00 - 85.5
38
152 - - 72.1
43
133 - - 67.7
44
130 - - 77.3
45
121 - - 72.5
48
120 - - 68.4
46
120 - - 78.7
50
120
3D
2yz0A00 - 99.1
47
120 - - 67.1
49
119 - - 88.1
51
108 - - 92.9
52
104
3D
2dmfA00 - 91.3
53
98 - - 48.0
54
90 - - 76.5
55
88 - - 70.7
57
86
3D
1ukxA00 - 81.7
56
86 - - 76.0
58
84 - - 77.3
59
79 - - 57.9
62
78
3D
2ybfA00 - 40.0
61
76 - - 70.8
60
UbcB
76 - - 95.2
63
E2
73 - - 77.8
101
72
3D
4ddiC01 - 51.9
64
71
3D
2ebmA00 - 84.6
65
69 - - 37.2
66
66 - - 59.2
67
58
3D
1yrvA00 - 76.2
68
57 - - 72.6
69
56 - - 34.8
70
55
3D
4y1lC00 - 70.3
72
50
3D
3we5B00 - 91.0
71
48 - - 76.2
73
48
3D
3e95B00 - 71.1
78
46
3D
2z5dB00 - 24.1
74
45 - - 39.6
75
Gir2
43 - - 96.9
76
42 - - 51.7
77
42 - - 70.6
79
42 - - 36.3
80
41 - - 53.0
81
38
3D
3zqsB01 - 81.3
82
35 - - 34.2
84
34 - - 11.1
83
34 - - 87.6
85
31 - - 34.3
86
31 - - 89.4
88
29
3D
2pwqA00 - 53.0
89
28 - - 80.2
87
28 - - 53.5
91
25 - - 58.7
90
25 - - 85.6
92
24 - - 70.6
96
22
3D
4bwfA00 - 79.9
93
UbcF
22 - - 74.7
94
20 - - 80.9
95
19 - - 9.7
97
18 - - 77.2
99
17 - - 78.9
98
UbcJ
17 - - 81.4
100
16 - - 59.7
102
15 - - 65.2
103
15 - - 67.9
108
14 - - 79.4
105
14 - - 1.4
109
14 - - 94.1
106
14 - - 14.8
107
14 - - 72.7
104
14 - - 2.1
112
13 - - 90.8
111
13 - - 0.0
110
13 - - 85.0
113
12 - - 29.6
114
12 - - 19.9
116
11 - - 11.9
115
11 - - 92.6
117
10 - - 8.5
120
10 - - 53.3
119
10 - - 13.3
118
10 - - 17.2
127
9 - - 1.5
128
9 - - 37.0
132
9 - - 94.3
129
9 - - 18.7
124
9 - - 11.1
131
9 - - 39.9
121
9 - - 84.7
130
9 - - 0.8
122
9 - - 22.8
125
9 - - 22.3
126
9 - - 64.8
133
9 - - 77.6
123
9 - - 11.9
134
9 - - 73.3
136
8 - - 72.2
137
8 - - 5.3
139
8 - - 14.8
135
8 - - 17.8
138
8 - - 10.0
140
8 - - 84.9
142
7 - - 72.3
145
7 - - 38.7
141
7 - - 76.4
146
7 - - 76.8
144
7 - - 2.1
143
7 - - 30.2
153
6 - - 19.1
154
6 - - 62.6
147
6 - - 21.5
149
6 - - 6.9
152
6 - - 83.6
148
6 - - 10.8
151
6 - - 3.2
150
6 - - 9.5
155
5 - - 6.0
158
5 - - 11.4
165
5 - - 35.7
168
5 - - 88.8
161
5 - - 7.3
157
5 - - 0.8
164
5 - - 10.9
160
5 - - 8.6
167
5 - - 38.9
163
5 - - 0.0
156
5 - - 13.4
159
5 - - 75.1
162
5 - - 0.0
166
5 - - 76.1
170
4 - - 68.0
175
4 - - 0.0
178
4 - - 14.6
174
4 - - 3.1
179
4 - - 71.0
177
4 - - 9.0
173
4 - - 6.2
171
4 - - 88.4
176
4 - - 37.9
169
4 - - 39.6
172
4 - - 21.3
180
3 - - 59.3
191
3 - - 12.9
187
3 - - 11.0
198
3 - - 59.4
202
3 - - 42.2
184
3 - - 2.6
181
3 - - 54.1
200
3 - - 11.3
192
3 - - 9.4
199
3 - - 63.6
195
3 - - 12.8
188
3 - - 1.0
183
3 - - 32.0
203
3 - - 70.9
204
3 - - 19.2
193
3 - - 5.0
189
3 - - 0.0
182
3 - - 60.3
239
3
3D
1y8xA00 - 29.2
186
3 - - 4.5
196
3 - - 1.6
194
3 - - 5.5
197
3 - - 54.8
201
3 - - 19.2
190
3 - - 3.7
185
3 - - 7.0
246
2 - - 44.5
262
2 - - 36.3
212
Conjugating enzyme
2 - - 42.1
232
2 - - 6.5
225
2 - - 8.9
207
2 - - 32.7
257
2 - - 0.0
229
2 - - 0.0
222
2 - - 0.0
217
2 - - 14.3
247
2 - - 35.5
209
2 - - 32.9
210
2 - - 19.5
252
2 - - 1.7
242
2 - - 2.5
254
2 - - 8.6
213
2 - - 42.2
224
2 - - 11.4
263
2 - - 40.5
233
2 - - 0.0
243
2 - - 40.0
228
2 - - 0.0
238
2 - - 36.4
253
2 - - 0.0
258
2 - - 3.1
248
2 - - 1.8
211
2 - - 37.8
236
2 - - 0.0
218
2 - - 15.8
234
2 - - 9.1
221
2 - - 24.9
260
RING finger
2 - - 0.0
205
2 - - 22.6
227
2 - - 0.0
264
2 - - 35.0
255
2 - - 0.0
250
2 - - 2.3
259
2 - - 0.0
249
2 - - 0.0
240
2 - - 16.5
230
2 - - 9.0
214
2 - - 21.7
219
2 - - 15.5
206
2 - - 33.5
220
2 - - 20.9
226
2 - - 0.0
244
UBC1 homolog
2 - - 5.9
237
2 - - 7.9
235
2 - - 1.4
265
2 - - 29.2
251
2 - - 0.0
256
2 - - 0.0
215
2 - - 13.0
245
2 - - 35.2
208
2 - - 35.5
241
2 - - 0.0
266
2 - - 46.9
231
2 - - 0.0
261
2 - - 25.2
223
2 - - 0.0
216
2 - - 13.5
350
1 - - 0.0
340
1 - - 0.0
311
1 - - 0.0
285
1 - - 0.0
308
1 - - 0.0
301
1 - - 0.0
366
1 - - 0.0
272
1 - - 0.0
294
1 - - 0.0
349
1 - - 0.0
323
1 - - 0.0
359
1 - - 0.0
330
1 - - 0.0
360
1 - - 0.0
353
1 - - 0.0
375
1 - - 0.0
278
1 - - 0.0
361
1 - - 0.0
307
1 - - 0.0
326
1 - - 0.0
335
1 - - 0.0
299
1 - - 0.0
315
1 - - 0.0
305
1 - - 0.0
281
1 - - 0.0
317
1 - - 0.0
284
1 - - 0.0
289
1 - - 0.0
319
1 - - 0.0
344
1 - - 0.0
336
1 - - 0.0
383
1 - - 0.0
290
UBC6 homolog, yeast
1 - - 0.0
365
1 - - 0.0
271
1 - - 0.0
382
1 - - 0.0
367
1 - - 0.0
351
1 - - 0.0
342
1 - - 0.0
341
1 - - 0.0
309
1 - - 0.0
329
1 - - 0.0
346
1 - - 0.0
279
1 - - 0.0
372
1 - - 0.0
293
1 - - 0.0
322
1 - - 0.0
310
1 - - 0.0
267
1 - - 0.0
354
1 - - 0.0
316
1 - - 0.0
280
1 - - 0.0
273
1 - - 0.0
314
1 - - 0.0
355
1 - - 0.0
334
1 - - 0.0
302
1 - - 0.0
362
1 - - 0.0
376
1 - - 0.0
298
1 - - 0.0
371
1 - - 0.0
339
1 - - 0.0
268
1 - - 0.0
345
1 - - 0.0
318
1 - - 0.0
356
1 - - 0.0
325
1 - - 0.0
378
1 - - 0.0
337
1 - - 0.0
288
1 - - 0.0
381
1 - - 0.0
373
1 - - 0.0
287
1 - - 0.0
333
1 - - 0.0
274
1 - - 0.0
303
1 - - 0.0
276
1 - - 0.0
347
1 - - 0.0
320
1 - - 0.0
377
1 - - 0.0
338
1 - - 0.0
328
1 - - 0.0
269
1 - - 0.0
363
1 - - 0.0
313
1 - - 0.0
357
1 - - 0.0
297
1 - - 0.0
283
1 - - 0.0
358
1 - - 0.0
331
1 - - 0.0
348
1 - - 0.0
364
1 - - 0.0
324
1 - - 0.0
379
1 - - 0.0
295
1 - - 0.0
312
1 - - 0.0
370
1 - - 0.0
380
1 - - 0.0
300
1 - - 0.0
286
1 - - 0.0
296
1 - - 0.0
275
1 - - 0.0
352
1 - - 0.0
369
1 - - 0.0
332
1 - - 0.0
368
1 - - 0.0
292
1 - - 0.0
291
1 - - 0.0
374
1 - - 0.0
327
1 - - 0.0
270
1 - - 0.0
384
1 - - 0.0
343
1 - - 0.0
321
1 - - 0.0
282
1 - - 0.0
277
1 - - 0.0
304
1 - - 0.0
306
1 - - 0.0