The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"C2 domain
".
FunFam 78: Extended synaptotagmin 2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 18 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
|
3 | Q3TZZ7 (/ISS) Q5FWL4 (/ISS) Q7ZWU7 (/ISS) |
|
Phosphatidylethanolamine binding GO:0008429
Interacting selectively and non-covalently with phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine.
|
3 | Q3TZZ7 (/ISS) Q5FWL4 (/ISS) Q7ZWU7 (/ISS) |
|
Phosphatidylcholine binding GO:0031210
Interacting selectively and non-covalently with phosphatidylcholine, a class of glycophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of choline.
|
3 | Q3TZZ7 (/ISS) Q5FWL4 (/ISS) Q7ZWU7 (/ISS) |
|
Phosphatidylinositol binding GO:0035091
Interacting selectively and non-covalently with any inositol-containing glycerophospholipid, i.e. phosphatidylinositol (PtdIns) and its phosphorylated derivatives.
|
3 | Q3TZZ7 (/ISS) Q5FWL4 (/ISS) Q7ZWU7 (/ISS) |
|
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
|
1 | A0FGR8 (/IDA) |
|
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
|
1 | Q3TZZ7 (/ISO) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | A0FGR8 (/IPI) |
|
Calcium-dependent phospholipid binding GO:0005544
Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester, in the presence of calcium.
|
1 | A0FGR8 (/IDA) |
|
Calcium-dependent phospholipid binding GO:0005544
Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester, in the presence of calcium.
|
1 | Q3TZZ7 (/ISO) |
|
Phosphatidylethanolamine binding GO:0008429
Interacting selectively and non-covalently with phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine.
|
1 | A0FGR8 (/IDA) |
|
Phosphatidylethanolamine binding GO:0008429
Interacting selectively and non-covalently with phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine.
|
1 | Q3TZZ7 (/ISO) |
|
Phosphatidylcholine binding GO:0031210
Interacting selectively and non-covalently with phosphatidylcholine, a class of glycophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of choline.
|
1 | A0FGR8 (/IDA) |
|
Phosphatidylcholine binding GO:0031210
Interacting selectively and non-covalently with phosphatidylcholine, a class of glycophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of choline.
|
1 | Q3TZZ7 (/ISO) |
|
Phosphatidylinositol binding GO:0035091
Interacting selectively and non-covalently with any inositol-containing glycerophospholipid, i.e. phosphatidylinositol (PtdIns) and its phosphorylated derivatives.
|
1 | A0FGR8 (/IDA) |
|
Phosphatidylinositol binding GO:0035091
Interacting selectively and non-covalently with any inositol-containing glycerophospholipid, i.e. phosphatidylinositol (PtdIns) and its phosphorylated derivatives.
|
1 | Q3TZZ7 (/ISO) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
1 | A0FGR8 (/IPI) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
1 | Q3TZZ7 (/ISO) |
|
Cadherin binding GO:0045296
Interacting selectively and non-covalently with cadherin, a type I membrane protein involved in cell adhesion.
|
1 | A0FGR8 (/HDA) |
There are 1 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Glycosphingolipid metabolic process GO:0006687
The chemical reactions and pathways involving glycosphingolipids, any compound with residues of sphingoid and at least one monosaccharide.
|
1 | A0FGR8 (/TAS) |
There are 16 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Intrinsic component of endoplasmic reticulum membrane GO:0031227
The component of the endoplasmic reticulum membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
|
3 | Q3TZZ7 (/ISS) Q5FWL4 (/ISS) Q7ZWU7 (/ISS) |
|
Extrinsic component of cytoplasmic side of plasma membrane GO:0031234
The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to its cytoplasmic surface, but not integrated into the hydrophobic region.
|
3 | Q3TZZ7 (/ISS) Q5FWL4 (/ISS) Q7ZWU7 (/ISS) |
|
Organelle membrane contact site GO:0044232
A zone of apposition between the membranes of an organelle with another membrane, either that of another organelle or the plasma membrane, structured by bridging complexes. Membrane contact sites (MCSs) are specialized for communication, including the efficient traffic of small molecules such as Ca2+ ions and lipids, as well as enzyme-substrate interactions.
|
3 | Q3TZZ7 (/ISS) Q5FWL4 (/ISS) Q7ZWU7 (/ISS) |
|
Endoplasmic reticulum-plasma membrane contact site GO:0140268
A contact site between the endoplasmic reticulum membrane and the plasma membrane, structured by bridging complexes.
|
3 | Q3TZZ7 (/ISS) Q5FWL4 (/ISS) Q7ZWU7 (/ISS) |
|
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
|
1 | A0FGR8 (/TAS) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | A0FGR8 (/IDA) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q3TZZ7 (/ISO) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | A0FGR8 (/HDA) |
|
Intrinsic component of endoplasmic reticulum membrane GO:0031227
The component of the endoplasmic reticulum membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
|
1 | A0FGR8 (/IDA) |
|
Intrinsic component of endoplasmic reticulum membrane GO:0031227
The component of the endoplasmic reticulum membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
|
1 | Q3TZZ7 (/ISO) |
|
Extrinsic component of cytoplasmic side of plasma membrane GO:0031234
The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to its cytoplasmic surface, but not integrated into the hydrophobic region.
|
1 | A0FGR8 (/IMP) |
|
Extrinsic component of cytoplasmic side of plasma membrane GO:0031234
The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to its cytoplasmic surface, but not integrated into the hydrophobic region.
|
1 | Q3TZZ7 (/ISO) |
|
Organelle membrane contact site GO:0044232
A zone of apposition between the membranes of an organelle with another membrane, either that of another organelle or the plasma membrane, structured by bridging complexes. Membrane contact sites (MCSs) are specialized for communication, including the efficient traffic of small molecules such as Ca2+ ions and lipids, as well as enzyme-substrate interactions.
|
1 | A0FGR8 (/IDA) |
|
Organelle membrane contact site GO:0044232
A zone of apposition between the membranes of an organelle with another membrane, either that of another organelle or the plasma membrane, structured by bridging complexes. Membrane contact sites (MCSs) are specialized for communication, including the efficient traffic of small molecules such as Ca2+ ions and lipids, as well as enzyme-substrate interactions.
|
1 | Q3TZZ7 (/ISO) |
|
Endoplasmic reticulum-plasma membrane contact site GO:0140268
A contact site between the endoplasmic reticulum membrane and the plasma membrane, structured by bridging complexes.
|
1 | A0FGR8 (/IDA) |
|
Endoplasmic reticulum-plasma membrane contact site GO:0140268
A contact site between the endoplasmic reticulum membrane and the plasma membrane, structured by bridging complexes.
|
1 | Q3TZZ7 (/ISO) |