The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
C2 domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 166: Protein C2-DOMAIN ABA-RELATED 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 12 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
GTPase activator activity GO:0005096
Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
17 A2X479 (/ISS) A2X479 (/ISS) A2X479 (/ISS) A2X479 (/ISS) A2X479 (/ISS) A2X479 (/ISS) A2X479 (/ISS) Q9C6B7 (/ISS) Q9C6B7 (/ISS) Q9C8Y2 (/ISS)
(7 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
11 Q6YWF1 (/IPI) Q6YWF1 (/IPI) Q6YWF1 (/IPI) Q6YWF1 (/IPI) Q6YWF1 (/IPI) Q6YWF1 (/IPI) Q6YWF1 (/IPI) Q9FHP6 (/IPI) Q9FHP6 (/IPI) Q9LVH4 (/IPI)
(1 more)
GTPase activator activity GO:0005096
Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
7 Q6YWF1 (/IDA) Q6YWF1 (/IDA) Q6YWF1 (/IDA) Q6YWF1 (/IDA) Q6YWF1 (/IDA) Q6YWF1 (/IDA) Q6YWF1 (/IDA)
Phospholipid binding GO:0005543
Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester.
6 Q9C6B7 (/ISS) Q9C6B7 (/ISS) Q9C8Y2 (/ISS) Q9FIK8 (/ISS) Q9FIK8 (/ISS) Q9LP65 (/ISS)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
4 Q9FHP6 (/IDA) Q9FHP6 (/IDA) Q9LVH4 (/IDA) Q9LVH4 (/IDA)
Phospholipid binding GO:0005543
Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester.
4 Q9FHP6 (/IMP) Q9FHP6 (/IMP) Q9LVH4 (/IMP) Q9LVH4 (/IMP)
Lipid binding GO:0008289
Interacting selectively and non-covalently with a lipid.
2 Q9LVH4 (/IDA) Q9LVH4 (/IDA)
Lipid binding GO:0008289
Interacting selectively and non-covalently with a lipid.
2 Q9FHP6 (/ISS) Q9FHP6 (/ISS)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
2 Q9LVH4 (/IDA) Q9LVH4 (/IDA)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
2 Q9FHP6 (/ISS) Q9FHP6 (/ISS)
Protein self-association GO:0043621
Interacting selectively and non-covalently with a domain within the same polypeptide.
2 Q9LVH4 (/IDA) Q9LVH4 (/IDA)
Protein self-association GO:0043621
Interacting selectively and non-covalently with a domain within the same polypeptide.
2 Q9FHP6 (/ISS) Q9FHP6 (/ISS)

There are 11 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Positive regulation of GTPase activity GO:0043547
Any process that activates or increases the activity of a GTPase.
17 A2X479 (/ISS) A2X479 (/ISS) A2X479 (/ISS) A2X479 (/ISS) A2X479 (/ISS) A2X479 (/ISS) A2X479 (/ISS) Q9C6B7 (/ISS) Q9C6B7 (/ISS) Q9C8Y2 (/ISS)
(7 more)
Response to salt stress GO:0009651
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
9 Q6YWF1 (/IDA) Q6YWF1 (/IDA) Q6YWF1 (/IDA) Q6YWF1 (/IDA) Q6YWF1 (/IDA) Q6YWF1 (/IDA) Q6YWF1 (/IDA) Q9LVH4 (/IDA) Q9LVH4 (/IDA)
Positive regulation of response to salt stress GO:1901002
Any process that activates or increases the frequency, rate or extent of response to salt stress.
9 Q6YWF1 (/IMP) Q6YWF1 (/IMP) Q6YWF1 (/IMP) Q6YWF1 (/IMP) Q6YWF1 (/IMP) Q6YWF1 (/IMP) Q6YWF1 (/IMP) Q9LVH4 (/IMP) Q9LVH4 (/IMP)
Response to wounding GO:0009611
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
7 Q6YWF1 (/IEP) Q6YWF1 (/IEP) Q6YWF1 (/IEP) Q6YWF1 (/IEP) Q6YWF1 (/IEP) Q6YWF1 (/IEP) Q6YWF1 (/IEP)
Response to salt stress GO:0009651
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
7 A2X479 (/ISS) A2X479 (/ISS) A2X479 (/ISS) A2X479 (/ISS) A2X479 (/ISS) A2X479 (/ISS) A2X479 (/ISS)
Positive regulation of GTPase activity GO:0043547
Any process that activates or increases the activity of a GTPase.
7 Q6YWF1 (/IDA) Q6YWF1 (/IDA) Q6YWF1 (/IDA) Q6YWF1 (/IDA) Q6YWF1 (/IDA) Q6YWF1 (/IDA) Q6YWF1 (/IDA)
Positive regulation of response to salt stress GO:1901002
Any process that activates or increases the frequency, rate or extent of response to salt stress.
7 A2X479 (/ISS) A2X479 (/ISS) A2X479 (/ISS) A2X479 (/ISS) A2X479 (/ISS) A2X479 (/ISS) A2X479 (/ISS)
Positive regulation of defense response to bacterium, incompatible interaction GO:1902479
Any process that activates or increases the frequency, rate or extent of defense response to bacterium, incompatible interaction.
7 Q6YWF1 (/IMP) Q6YWF1 (/IMP) Q6YWF1 (/IMP) Q6YWF1 (/IMP) Q6YWF1 (/IMP) Q6YWF1 (/IMP) Q6YWF1 (/IMP)
Positive regulation of abscisic acid-activated signaling pathway GO:0009789
Any process that activates or increases the frequency, rate or extent of abscisic acid (ABA) signaling.
5 Q9FHP6 (/IMP) Q9FHP6 (/IMP) Q9LP65 (/IMP) Q9LVH4 (/IMP) Q9LVH4 (/IMP)
Positive regulation of abscisic acid-activated signaling pathway GO:0009789
Any process that activates or increases the frequency, rate or extent of abscisic acid (ABA) signaling.
5 Q9C6B7 (/ISS) Q9C6B7 (/ISS) Q9C8Y2 (/ISS) Q9FIK8 (/ISS) Q9FIK8 (/ISS)
Positive regulation of defense response to bacterium, incompatible interaction GO:1902479
Any process that activates or increases the frequency, rate or extent of defense response to bacterium, incompatible interaction.
2 Q9LVH4 (/ISS) Q9LVH4 (/ISS)

There are 7 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
9 Q6YWF1 (/IDA) Q6YWF1 (/IDA) Q6YWF1 (/IDA) Q6YWF1 (/IDA) Q6YWF1 (/IDA) Q6YWF1 (/IDA) Q6YWF1 (/IDA) Q9LVH4 (/IDA) Q9LVH4 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
7 A2X479 (/ISS) A2X479 (/ISS) A2X479 (/ISS) A2X479 (/ISS) A2X479 (/ISS) A2X479 (/ISS) A2X479 (/ISS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
7 Q9FHP6 (/IDA) Q9FHP6 (/IDA) Q9FIK8 (/IDA) Q9FIK8 (/IDA) Q9LP65 (/IDA) Q9LVH4 (/IDA) Q9LVH4 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
6 Q9C6B7 (/ISS) Q9C6B7 (/ISS) Q9C8Y2 (/ISS) Q9FIK8 (/ISS) Q9FIK8 (/ISS) Q9LP65 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
5 Q9FHP6 (/IDA) Q9FHP6 (/IDA) Q9LP65 (/IDA) Q9LVH4 (/IDA) Q9LVH4 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
4 Q9C6B7 (/ISS) Q9C6B7 (/ISS) Q9C8Y2 (/ISS) Q9LP65 (/ISS)
Vacuole GO:0005773
A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.
2 Q9FIK8 (/IDA) Q9FIK8 (/IDA)