The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Translation factors
".
FunFam 24: Eukaryotic peptide chain release factor GTP-bindin...
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 9 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
6 | P15170 (/IPI) P15170 (/IPI) P15170 (/IPI) P15170 (/IPI) Q8IYD1 (/IPI) Q91855 (/IPI) |
|
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
5 | P15170 (/HDA) P15170 (/HDA) P15170 (/HDA) P15170 (/HDA) Q8IYD1 (/HDA) |
|
Translation release factor activity GO:0003747
Involved in catalyzing the release of a nascent polypeptide chain from a ribosome.
|
4 | P15170 (/IMP) P15170 (/IMP) P15170 (/IMP) P15170 (/IMP) |
|
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
|
4 | P15170 (/TAS) P15170 (/TAS) P15170 (/TAS) P15170 (/TAS) |
|
Translation release factor activity GO:0003747
Involved in catalyzing the release of a nascent polypeptide chain from a ribosome.
|
3 | A7YWL9 (/ISS) Q8R050 (/ISS) Q9N2G7 (/ISS) |
|
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
|
3 | M9PD08 (/NAS) P91944 (/NAS) Q9VK85 (/NAS) |
|
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
|
3 | M9PD08 (/ISS) P91944 (/ISS) Q9VK85 (/ISS) |
|
Translation termination factor activity GO:0008079
Functions in the termination of translation.
|
3 | M9PD08 (/ISS) P91944 (/ISS) Q9VK85 (/ISS) |
|
Translation release factor activity GO:0003747
Involved in catalyzing the release of a nascent polypeptide chain from a ribosome.
|
1 | Q8R050 (/ISO) |
There are 7 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184
The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins.
|
5 | P15170 (/TAS) P15170 (/TAS) P15170 (/TAS) P15170 (/TAS) Q8IYD1 (/TAS) |
|
G1/S transition of mitotic cell cycle GO:0000082
The mitotic cell cycle transition by which a cell in G1 commits to S phase. The process begins with the build up of G1 cyclin-dependent kinase (G1 CDK), resulting in the activation of transcription of G1 cyclins. The process ends with the positive feedback of the G1 cyclins on the G1 CDK which commits the cell to S phase, in which DNA replication is initiated.
|
4 | P15170 (/TAS) P15170 (/TAS) P15170 (/TAS) P15170 (/TAS) |
|
Protein methylation GO:0006479
The addition of a methyl group to a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom.
|
4 | P15170 (/IDA) P15170 (/IDA) P15170 (/IDA) P15170 (/IDA) |
|
Translational termination GO:0006415
The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code).
|
3 | M9PD08 (/IMP) P91944 (/IMP) Q9VK85 (/IMP) |
|
Translational termination GO:0006415
The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code).
|
3 | M9PD08 (/ISS) P91944 (/ISS) Q9VK85 (/ISS) |
|
Vasculature development GO:0001944
The process whose specific outcome is the progression of the vasculature over time, from its formation to the mature structure. The vasculature is an interconnected tubular multi-tissue structure that contains fluid that is actively transported around the organism.
|
1 | Q7T358 (/IMP) |
|
Protein methylation GO:0006479
The addition of a methyl group to a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom.
|
1 | Q8R050 (/ISO) |
There are 5 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
5 | P15170 (/TAS) P15170 (/TAS) P15170 (/TAS) P15170 (/TAS) Q8IYD1 (/TAS) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
3 | M9PD08 (/HDA) P91944 (/HDA) Q9VK85 (/HDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
3 | M9PD08 (/ISS) P91944 (/ISS) Q9VK85 (/ISS) |
|
Vacuole GO:0005773
A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.
|
1 | Q9LMS7 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q9LMS7 (/IDA) |