The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Translation factors
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
3327
3D
4r71C04 - 89.5
2
3197
3D
4r71C05 - 83.1
3
2709
3D
5o8wA02 - 91.5
4
2218 - - 97.5
5
1856
3D
5o8wA03 - 87.3
6
1650
3D
2efgA02 - 96.0
7
1410 - - 96.9
8
1335
3D
1d1nA00 - 94.3
9
1119
3D
3j81k02 - 99.4
10
988
3D
3b8hE03 - 89.0
11
927
3D
4zgqB00 - 93.0
12
900
3D
5an9A02 - 90.5
13
856
3D
4ncfB02 - 94.3
14
818 - - 93.3
15
779
3D
3cb4F02 - 96.7
16
756
3D
4zcmB02 - 92.9
17
735
3D
3e20J02 - 94.6
18
+
624
3D
1a8pA01 - 75.7
19
562 - - 92.2
20
555
3D
3mcaA01 - 86.9
21
540
3D
1umkA01 - 92.0
22
519 - - 94.0
23
505
3D
2deuB03 - 96.2
24
493
3D
5hxbX01 - 88.1
25
457
3D
1tllB03 - 92.4
26
449
3D
3wbkB04 - 97.5
27
417
3D
1zunB02 - 89.3
28
353 - - 73.7
29
348 - - 98.3
30
296 - - 86.7
36
293
3D
3fjoA03 - 82.2
31
293
3D
1zunB03 - 90.9
34
280
3D
1gvhA02 - 97.0
32
279
3D
2eixB01 - 93.1
33
265 - - 62.6
35
241 - - 94.9
37
234 - - 84.0
38
232
3D
1ddiA01 - 93.0
39
228 - - 71.5
40
228 - - 86.8
41
203
3D
5gxuB01 - 71.8
42
NAD
P
196
3D
1qfjD01 - 16.7
43
181 - - 70.4
48
177
3D
3lvbA01 - 79.0
44
+
177
3D
2xnjB01 - 57.1
45
NAD(+
144 - - 53.9
46
140 - - 76.4
47
137 - - 82.2
49
128 - - 84.8
50
127 - - 32.3
51
125 - - 91.9
75
123
3D
6i5mA03 - 97.5
54
123
3D
4kjzD03 - 99.3
52
120 - - 89.8
53
119 - - 75.4
55
111 - - 73.2
56
103 - - 88.1
57
101 - - 73.3
58
100 - - 32.6
59
96 - - 91.7
60
94 - - 85.7
61
92 - - 85.0
62
92
3D
2qtzA02 - 61.8
64
Na
+
89
3D
4u9uB01 - 54.7
63
89 - - 91.8
65
85 - - 80.7
68
82
3D
1xb2A02 - 68.2
70
80
3D
3p27B03 - 99.8
71
79
3D
1xb2A03 - 72.7
66
78 - - 86.9
67
78 - - 87.9
69
77 - - 98.0
73
76
3D
2bpoB03 - 68.2
72
73
3D
2crvA01 - 83.9
74
64 - - 0.0
76
63 - - 78.1
77
60 - - 73.6
78
58 - - 44.8
79
58 - - 83.9
80
57 - - 67.2
82
55 - - 90.1
81
P
55 - - 25.0
83
53 - - 74.4
85
50 - - 91.6
84
50 - - 85.7
86
49 - - 77.0
87
P
47 - - 19.5
89
43 - - 19.7
90
43 - - 88.9
88
43 - - 20.0
91
NoxA
40 - - 87.0
92
39 - - 82.0
93
37 - - 79.3
199
36
3D
4bprA01 - 22.8
94
33 - - 24.0
95
33 - - 72.1
96
32 - - 61.1
97
31 - - 55.0
99
30 - - 89.7
98
30 - - 79.4
100
29 - - 85.7
101
28 - - 20.5
102
27 - - 94.4
105
24 - - 67.1
104
24 - - 5.3
103
24 - - 64.6
108
23 - - 81.2
106
23 - - 81.2
107
23 - - 83.1
109
22 - - 70.4
110
22 - - 72.4
112
21 - - 13.2
111
21 - - 79.8
113
21 - - 93.6
130
21
3D
4dqlB01 - 69.8
114
21 - - 96.4
115
20 - - 87.8
116
19 - - 12.6
117
19 - - 3.2
120
19 - - 76.2
121
19 - - 82.2
119
19 - - 67.4
118
19 - - 5.3
127
18 - - 95.6
124
18 - - 33.1
122
18 - - 69.6
125
18 - - 80.8
126
18 - - 87.4
123
18 - - 24.5
128
17 - - 11.1
132
17 - - 3.7
129
17 - - 0.9
135
17 - - 0.0
131
17 - - 57.9
133
17 - - 44.5
134
17 - - 74.1
136
16 - - 0.0
137
16 - - 1.6
142
16 - - 5.8
165
16
3D
3p27B02 - 46.5
139
16 - - 9.0
141
16 - - 4.5
144
16 - - 67.3
138
16 - - 17.6
140
16 - - 6.4
143
16 - - 7.6
153
15 - - 0.0
147
15 - - 9.1
149
15 - - 8.0
145
15 - - 66.2
152
15 - - 74.3
148
15 - - 18.0
146
15 - - 24.7
151
15 - - 84.0
150
15 - - 11.6
155
14 - - 46.4
154
14 - - 81.0
158
14 - - 91.2
168
14
3D
4c0sB02 - 71.8
157
14 - - 4.4
156
14 - - 46.5
159
14 - - 88.6
161
13 - - 28.5
164
13 - - 0.0
160
13 - - 2.6
163
13 - - 12.1
162
13 - - 22.5
167
12 - - 43.5
169
12 - - 62.9
166
12 - - 42.7
170
11 - - 39.6
175
11 - - 27.8
174
11 - - 0.0
173
11 - - 11.3
171
11 - - 10.4
176
11 - - 20.9
172
11 - - 10.6
180
10 - - 85.8
187
10 - - 49.5
184
10 - - 4.8
181
10 - - 14.5
178
10 - - 29.2
351
10 - - 53.5
188
10 - - 59.1
183
10 - - 60.6
179
10 - - 16.4
177
10 - - 39.9
182
10 - - 43.5
186
10 - - 0.0
185
P
10 - - 17.7
191
9 - - 0.0
192
9 - - 0.0
195
9 - - 55.2
193
9 - - 7.7
189
9 - - 0.0
194
9 - - 1.5
190
9 - - 33.3
198
8 - - 87.9
202
8 - - 2.8
200
8 - - 13.5
203
8 - - 39.6
204
8 - - 0.0
205
8 - - 12.2
196
8 - - 43.2
197
8 - - 24.5
201
8 - - 2.6
212
7 - - 4.7
225
7 - - 77.1
207
7 - - 11.2
222
7 - - 48.3
217
7 - - 36.9
209
7 - - 37.0
210
7 - - 1.1
213
7 - - 4.2
224
7 - - 67.0
211
7 - - 8.3
218
NAD
P
7 - - 0.0
221
7 - - 39.2
227
7 - - 48.7
214
7 - - 41.2
219
7 - - 20.3
206
7 - - 41.3
220
7 - - 4.9
226
7 - - 65.5
215
7 - - 15.6
208
7 - - 38.1
223
7 - - 52.2
216
7 - - 9.0
232
6 - - 79.4
229
6 - - 10.1
242
6 - - 88.5
233
6 - - 34.3
243
6 - - 20.8
228
6 - - 4.9
238
6 - - 35.9
236
6 - - 5.5
234
6 - - 0.9
240
6 - - 36.9
230
6 - - 5.7
239
TuF-2
6 - - 50.4
237
6 - - 1.4
235
6 - - 14.6
241
6 - - 79.9
231
methionine synthase
6 - - 76.1
246
5 - - 13.0
262
5 - - 13.3
257
5 - - 0.0
247
5 - - 74.6
252
5 - - 4.9
254
5 - - 78.8
263
5 - - 55.8
253
5 - - 0.0
258
5 - - 57.9
248
5 - - 9.8
260
5 - - 0.0
264
5 - - 85.7
255
5 - - 9.6
250
5 - - 9.5
259
IF-2
5 - - 10.5
249
5 - - 47.7
244
5 - - 0.0
265
5 - - 18.5
251
5 - - 12.3
256
5 - - 0.0
245
5 - - 2.5
261
5 - - 1.5
285
4 - - 15.4
272
4 - - 9.8
278
4 - - 1.7
281
4 - - 75.7
284
4 - - 6.0
289
4 - - 17.8
290
4 - - 52.6
271
4 - - 5.4
279
4 - - 32.0
267
4 - - 3.1
280
4 - - 37.7
273
4 - - 8.6
268
4 - - 31.6
288
4 - - 45.7
287
4 - - 31.7
274
4 - - 4.7
276
4 - - 3.4
269
4 - - 59.8
283
4 - - 11.6
286
4 - - 60.7
275
4 - - 1.2
292
4 - - 37.8
291
4 - - 82.2
270
4 - - 17.3
266
4 - - 3.4
282
4 - - 10.3
277
4 - - 1.1
311
3 - - 8.8
308
3 - - 85.1
301
3 - - 0.0
294
3 - - 14.5
307
3 - - 14.3
299
3 - - 0.0
315
3 - - 31.3
305
3 - - 2.0
317
3 - - 12.1
319
3 - - 1.4
309
3 - - 6.7
293
4,6
3 - - 0.0
310
3 - - 10.1
316
3 - - 0.0
314
3 - - 31.7
302
3 - - 6.0
298
3 - - 10.2
318
3 - - 31.9
303
3 - - 0.0
320
3 - - 1.3
313
3 - - 11.4
297
3 - - 7.4
295
3 - - 0.0
312
3 - - 0.0
300
3 - - 9.4
296
3 - - 10.4
321
3 - - 13.5
304
3 - - 10.0
306
3 - - 15.4
350
2 - - 36.3
340
2 - - 0.0
391
2 - - 0.0
366
2 - - 0.0
349
2 - - 21.4
323
2 - - 10.3
359
2 - - 0.0
330
2 - - 0.0
360
2 - - 8.6
353
2 - - 50.2
375
2 - - 0.0
387
2 - - 2.0
395
2 - - 31.2
361
2 - - 6.3
326
2 - - 8.1
335
2 - - 6.2
344
2 - - 9.5
336
2 - - 0.0
383
2 - - 5.1
365
2 - - 0.0
382
2 - - 9.7
367
2 - - 2.7
342
2 - - 0.0
341
2 - - 0.0
392
2 - - 0.0
399
+
2 - - 45.2
386
2 - - 0.0
329
2 - - 9.0
346
2 - - 2.5
372
2 - - 10.9
322
2 - - 2.6
354
2 - - 48.1
355
2 - - 8.5
334
2 - - 0.0
362
2 - - 0.0
376
2 - - 2.3
371
2 - - 9.9
339
2 - - 0.0
345
2 - - 5.5
396
2 - - 39.7
356
2 - - 1.1
378
2 - - 6.6
325
2 - - 18.4
337
2 - - 0.0
389
2 - - 4.7
381
2 - - 0.0
373
2 - - 7.3
400
2 - - 46.9
333
2 - - 0.0
393
2 - - 2.1
347
2 - - 0.0
385
2 - - 0.0
377
2 - - 27.2
338
2 - - 0.0
328
NAD(+
2 - - 0.0
363
2 - - 0.0
397
P
2 - - 43.0
401
2 - - 45.8
357
2 - - 3.4
390
2 - - 1.0
358
2 - - 1.2
331
2 - - 5.5
348
2 - - 26.0
364
2 - - 1.8
388
2 - - 2.8
324
2 - - 0.0
379
2 - - 7.5
370
2 - - 0.0
380
2 - - 0.0
352
2 - - 42.0
369
2 - - 18.2
394
2 - - 0.0
332
2 - - 8.1
368
2 - - 0.0
374
2 - - 0.0
327
2 - - 0.0
384
2 - - 0.0
398
2 - - 45.8
343
2 - - 10.8
512
1 - - 0.0
463
1 - - 0.0
458
1 - - 0.0
517
1 - - 0.0
495
1 - - 0.0
486
1 - - 0.0
444
1 - - 0.0
508
1 - - 0.0
506
1 - - 0.0
456
1 - - 0.0
468
1 - - 0.0
413
1 - - 0.0
432
1 - - 0.0
526
1 - - 0.0
477
1 - - 0.0
449
1 - - 0.0
501
1 - - 0.0
490
1 - - 0.0
461
1 - - 0.0
425
1 - - 0.0
520
1 - - 0.0
532
1 - - 0.0
412
1 - - 0.0
440
1 - - 0.0
467
1 - - 0.0
481
1 - - 0.0
474
1 - - 0.0
472
1 - - 0.0
529
1 - - 0.0
457
1 - - 0.0
505
1 - - 0.0
419
1 - - 0.0
406
1 - - 0.0
421
1 - - 0.0
491
1 - - 0.0
408
1 - - 0.0
443
1 - - 0.0
431
1 - - 0.0
509
1 - - 0.0
523
1 - - 0.0
453
1 - - 0.0
488
1 - - 0.0
405
1 - - 0.0
507
1 - - 0.0
436
1 - - 0.0
525
1 - - 0.0
427
1 - - 0.0
426
1 - - 0.0
498
1 - - 0.0
483
1 - - 0.0
533
5-methylaminomethyl-2-thiouridylate
1 - - 0.0
462
1 - - 0.0
414
1 - - 0.0
476
1 - - 0.0
469
1 - - 0.0
511
1 - - 0.0
471
1 - - 0.0
502
1 - - 0.0
423
1 - - 0.0
422
1 - - 0.0
402
1 - - 0.0
464
1 - - 0.0
439
1 - - 0.0
407
1 - - 0.0
435
1 - - 0.0
494
1 - - 0.0
487
1 - - 0.0
448
1 - - 0.0
482
1 - - 0.0
499
1 - - 0.0
450
1 - - 0.0
473
1 - - 0.0
528
1 - - 0.0
451
1 - - 0.0
454
1 - - 0.0
410
1 - - 0.0
430
1 - - 0.0
447
1 - - 0.0
415
1 - - 0.0
480
1 - - 0.0
438
1 - - 0.0
417
1 - - 0.0
493
1 - - 0.0
534
1 - - 0.0
475
1 - - 0.0
515
1 - - 0.0
519
1 - - 0.0
446
1 - - 0.0
510
1 - - 0.0
424
Fragment
1 - - 0.0
434
1 - - 0.0
442
1 - - 0.0
465
1 - - 0.0
479
1 - - 0.0
524
1 - - 0.0
503
1 - - 0.0
484
1 - - 0.0
522
1 - - 0.0
459
1 - - 0.0
404
1 - - 0.0
516
1 - - 0.0
455
1 - - 0.0
530
1 - - 0.0
470
1 - - 0.0
437
1 - - 0.0
527
1 - - 0.0
418
1 - - 0.0
485
1 - - 0.0
460
1 - - 0.0
452
1 - - 0.0
416
1 - - 0.0
496
1 - - 0.0
445
1 - - 0.0
441
1 - - 0.0
428
1 - - 0.0
500
1 - - 0.0
514
1 - - 0.0
513
1 - - 0.0
492
1 - - 0.0
429
1 - - 0.0
409
1 - - 0.0
489
1 - - 0.0
521
1 - - 0.0
433
1 - - 0.0
518
1 - - 0.0
497
1 - - 0.0
411
1 - - 0.0
478
1 - - 0.0
504
1 - - 0.0
531
1 - - 0.0
420
1 - - 0.0
403
1 - - 0.0
466
1 - - 0.0