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CATH Superfamily 2.40.10.10

Trypsin-like serine proteases

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Trypsin-like serine proteases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 45: Replicase polyprotein 1a

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
3'-5'-exoribonuclease activity GO:0000175
Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule.
 15 P0C6X7 (/IDA) P0C6X7 (/IDA) P0C6X7 (/IDA) P0C6X7 (/IDA) P0C6X7 (/IDA) P0C6X7 (/IDA) P0C6X7 (/IDA) P0C6X7 (/IDA) P0C6X7 (/IDA) P0C6X7 (/IDA)
(5 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
 15 P0C6X7 (/IPI) P0C6X7 (/IPI) P0C6X7 (/IPI) P0C6X7 (/IPI) P0C6X7 (/IPI) P0C6X7 (/IPI) P0C6X7 (/IPI) P0C6X7 (/IPI) P0C6X7 (/IPI) P0C6X7 (/IPI)
(5 more)
Cysteine-type endopeptidase activity GO:0004197
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
 1 P0C6V1 (/IMP)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Viral transcription GO:0019083
The process by which a viral genome, or part of a viral genome, is transcribed within the host cell.
 15 P0C6X7 (/IMP) P0C6X7 (/IMP) P0C6X7 (/IMP) P0C6X7 (/IMP) P0C6X7 (/IMP) P0C6X7 (/IMP) P0C6X7 (/IMP) P0C6X7 (/IMP) P0C6X7 (/IMP) P0C6X7 (/IMP)
(5 more)
Self proteolysis GO:0097264
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds.
 1 P0C6V1 (/IDA)
Self proteolysis GO:0097264
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds.
 1 P0C6V0 (/IMP)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.