The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Leishmanolysin domain 4
".
FunFam 4: GP63, leishmanolysin
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein tyrosine phosphatase activator activity GO:0008160
Increases the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a tyrosyl phenolic group of a protein.
|
4 | Q4QHG9 (/IDA) Q4QHH0 (/IDA) Q4QHH1 (/IDA) Q4QHH2 (/IDA) |
|
Metallopeptidase activity GO:0008237
Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
|
1 | P08148 (/IMP) |
There are 5 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Modulation by symbiont of host nitric oxide-mediated signal transduction GO:0044081
Any process in which a symbiont organism modulates the rate, frequency or extent of nitric oxide mediated signal transduction in its host organism. Nitric oxide mediated signal transduction is a series of molecular signals mediated by the detection of nitric oxide (NO).
|
4 | Q4QHG9 (/IMP) Q4QHH0 (/IMP) Q4QHH1 (/IMP) Q4QHH2 (/IMP) |
|
Modulation by symbiont of host protein kinase-mediated signal transduction GO:0075130
Any process in which the symbiont modulates the frequency, rate or extent of protein kinase-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
|
4 | Q4QHG9 (/IMP) Q4QHH0 (/IMP) Q4QHH1 (/IMP) Q4QHH2 (/IMP) |
|
Positive regulation by symbiont of host cytokine secretion GO:0036523
Any process in which an organism activates, maintains or increases the frequency, rate or extent of cytokine secretion in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
|
1 | P08148 (/IMP) |
|
Catabolism by symbiont of host protein GO:0052014
The chemical reactions and pathways performed by an organism resulting in the breakdown of protein macromolecules within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
|
1 | P08148 (/IMP) |
|
Modulation by symbiont of host inflammatory response GO:0052032
Any process in which an organism modulates the frequency, rate or extent of the inflammatory response of the host organism; the inflammatory response is the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The host is defined as the larger of the organisms involved in a symbiotic interaction.
|
1 | P08148 (/IMP) |
There are 1 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Host cell nucleus GO:0042025
A membrane-bounded organelle as it is found in the host cell in which chromosomes are housed and replicated. The host is defined as the larger of the organisms involved in a symbiotic interaction.
|
4 | Q4QHG9 (/IDA) Q4QHH0 (/IDA) Q4QHH1 (/IDA) Q4QHH2 (/IDA) |