The developmentally regulated remodeling of neuronal projections such as pruning to eliminate the extra dendrites and axons projections set up in early stages of nervous system development.

Any intracellular signal transduction in which the signal is passed on within the cell via calcium ions.

A process in which a calcium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.

A process in which a calcium ion is transported from one side of a membrane to the other by means of a high voltage-gated calcium channel.

Any process that activates or increases the frequency, rate or extent of high voltage-gated calcium channel activity.

The directed movement of calcium ions (Ca2+) into the cytosol.

A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane.

Any process that modulates the rate, frequency or extent of membrane repolarization during an action potential. Membrane repolarization is the process in which membrane potential changes in the repolarizing direction, towards the resting potential.

The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

A series of molecular signals initiated by the cross-linking of an antigen receptor on a T cell.

The series of events involved in the perception of pain in which a mechanical stimulus is received and converted into a molecular signal.

The series of events involved in the perception of pain in which a mechanical stimulus is received and converted into a molecular signal.

The process in which membrane potential decreases with respect to its steady-state potential, usually from negative potential to a more positive potential. For example, the initial depolarization during the rising phase of an action potential is in the direction from the negative steady-state resting potential towards the positive membrane potential that will be the peak of the action potential.

The directed movement of calcium ions (Ca2+) into the cytosol.

The directed movement of calcium ions (Ca2+) into the cytosol.

Transfer of an organized electrical impulse across the heart to coordinate the contraction of cardiac muscles. The process begins with generation of an action potential (in the sinoatrial node (SA) in humans) and ends with a change in the rate, frequency, or extent of the contraction of the heart muscles.

A process in which a calcium ion is transported from one side of a membrane to the other by means of a high voltage-gated calcium channel.

A process in which a calcium ion is transported from one side of a membrane to the other by means of a high voltage-gated calcium channel.

A process in which a calcium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.

A process in which a calcium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.

A process in which a calcium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.

A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane.

A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane.

Any process that increases the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein.

Any process that increases the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein.

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the deprivation of oxygen and glucose.

Any process that modulates the rate, frequency or extent of membrane repolarization during an action potential. Membrane repolarization is the process in which membrane potential changes in the repolarizing direction, towards the resting potential.

Any process that modulates the rate, frequency or extent of membrane repolarization during an action potential. Membrane repolarization is the process in which membrane potential changes in the repolarizing direction, towards the resting potential.

Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated calcium channel activity.

Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated calcium channel activity.

Any process that activates or increases the frequency, rate or extent of voltage-gated calcium channel activity.

Any process that activates or increases the frequency, rate or extent of voltage-gated calcium channel activity.

Any process that activates or increases the frequency, rate or extent of high voltage-gated calcium channel activity.

Any process that activates or increases the frequency, rate or extent of high voltage-gated calcium channel activity.

Any process that modulates the frequency, rate or extent of membrane hyperpolarization.

Any process that modulates the frequency, rate or extent of membrane hyperpolarization.

Any process that stops, prevents or reduces the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch.

Any process that stops, prevents or reduces the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch.

Any process that enhances the establishment or increases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.

Any process that enhances the establishment or increases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.

A protein complex that forms a transmembrane channel through which calcium ions may pass in response to changes in membrane potential.

A type of voltage-dependent calcium channel responsible for excitation-contraction coupling of skeletal, smooth, and cardiac muscle. 'L' stands for 'long-lasting' referring to the length of activation.

A protein complex that forms a transmembrane channel through which calcium ions may pass in response to changes in membrane potential.

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

A protein complex that forms a transmembrane channel through which calcium ions may pass in response to changes in membrane potential.

A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

The region of the plasma membrane located at the apical end of the cell.

The region of the plasma membrane located at the apical end of the cell.

A type of voltage-dependent calcium channel responsible for excitation-contraction coupling of skeletal, smooth, and cardiac muscle. 'L' stands for 'long-lasting' referring to the length of activation.

A type of voltage-dependent calcium channel responsible for excitation-contraction coupling of skeletal, smooth, and cardiac muscle. 'L' stands for 'long-lasting' referring to the length of activation.

A type of voltage-dependent calcium channel responsible for excitation-contraction coupling of skeletal, smooth, and cardiac muscle. 'L' stands for 'long-lasting' referring to the length of activation.