The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
SH3 Domains
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 254: Myosin I MyoA/Myo5

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Microfilament motor activity GO:0000146
Catalysis of movement along a microfilament, coupled to the hydrolysis of a nucleoside triphosphate (usually ATP).
2 P36006 (/TAS) P36006 (/TAS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 P36006 (/IPI) P36006 (/IPI)
Myosin binding GO:0017022
Interacting selectively and non-covalently with any part of a myosin complex; myosins are any of a superfamily of molecular motor proteins that bind to actin and use the energy of ATP hydrolysis to generate force and movement along actin filaments.
2 P36006 (/IPI) P36006 (/IPI)

There are 21 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Exocytosis GO:0006887
A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for exemple of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell.
2 P36006 (/TAS) P36006 (/TAS)
Endocytosis GO:0006897
A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.
2 P36006 (/TAS) P36006 (/TAS)
Receptor-mediated endocytosis GO:0006898
An endocytosis process in which cell surface receptors ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles.
2 Q2US45 (/IMP) Q59MQ0 (/IMP)
Response to osmotic stress GO:0006970
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
2 P36006 (/TAS) P36006 (/TAS)
Bipolar cellular bud site selection GO:0007121
The process of defining subsequent sites of bud emergence such that budding takes place at alternating poles of a budding cell.
2 P36006 (/TAS) P36006 (/TAS)
Fungal-type cell wall organization GO:0031505
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fungal-type cell wall.
2 P36006 (/TAS) P36006 (/TAS)
Actin cortical patch localization GO:0051666
Any process in which actin cortical patches are transported to, or maintained in, a specific location. An actin cortical patch is a discrete actin-containing structure found just beneath the plasma membrane in fungal cells.
2 P36006 (/IGI) P36006 (/IGI)
Actin cortical patch localization GO:0051666
Any process in which actin cortical patches are transported to, or maintained in, a specific location. An actin cortical patch is a discrete actin-containing structure found just beneath the plasma membrane in fungal cells.
2 Q00647 (/IMP) Q59MQ0 (/IMP)
Positive regulation of Arp2/3 complex-mediated actin nucleation GO:2000601
Any process that activates or increases the frequency, rate or extent of Arp2/3 complex-mediated actin nucleation.
2 P36006 (/IDA) P36006 (/IDA)
Endocytosis GO:0006897
A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.
1 Q59MQ0 (/IMP)
Bipolar cellular bud site selection GO:0007121
The process of defining subsequent sites of bud emergence such that budding takes place at alternating poles of a budding cell.
1 Q59MQ0 (/IMP)
Cellular response to starvation GO:0009267
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment.
1 Q59MQ0 (/IMP)
Cell tip growth GO:0009932
Growth that occurs specifically at the tip of a cell.
1 Q00647 (/IMP)
Actin cytoskeleton organization GO:0030036
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
1 Q59MQ0 (/IMP)
Filamentous growth GO:0030447
The process in which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.
1 Q59MQ0 (/IMP)
Fungal-type cell wall organization GO:0031505
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fungal-type cell wall.
1 Q59MQ0 (/IMP)
Phenotypic switching GO:0036166
A reversible switch of a cell from one cell type or form to another, at a frequency above the expected frequency for somatic mutations. Phenotypic switching involves changes in cell morphology and altered gene expression patterns. For example, Candida albicans switches from white cells to opaque cells for sexual mating. Phenotypic switching also occurs in multicellular organisms; smooth muscle cells (SMCs) exhibit phenotypic transitions to allow rapid adaption to fluctuating environmental cues.
1 Q59MQ0 (/IMP)
Filamentous growth of a population of unicellular organisms in response to starvation GO:0036170
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to deprivation of nourishment.
1 Q59MQ0 (/IMP)
Filamentous growth of a population of unicellular organisms in response to biotic stimulus GO:0036180
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a biotic (living) stimulus.
1 Q59MQ0 (/IMP)
Cell growth mode switching, budding to filamentous GO:0036187
The process in which a cell switches from growing as a round budding cell to growing as a filament (elongated cells attached end-to-end). An example of this is the yeast-hyphal transition of Candida albicans.
1 Q59MQ0 (/IMP)
Actin cortical patch localization GO:0051666
Any process in which actin cortical patches are transported to, or maintained in, a specific location. An actin cortical patch is a discrete actin-containing structure found just beneath the plasma membrane in fungal cells.
1 Q00647 (/IDA)

There are 10 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Hyphal tip GO:0001411
The end, or tip, of a fungal hypha, where polarized growth occurs during hyphal elongation.
3 Q00647 (/IDA) Q2US45 (/IDA) Q59MQ0 (/IDA)
Actin cortical patch GO:0030479
An endocytic patch that consists of an actin-containing structure found at the plasma membrane in cells; formed of networks of branched actin filaments that lie just beneath the plasma membrane and assemble, move, and disassemble rapidly. An example of this is the actin cortical patch found in Saccharomyces cerevisiae.
3 Q00647 (/IDA) Q2US45 (/IDA) Q59MQ0 (/IDA)
Cell septum GO:0030428
A structure composed of peptidoglycan and often chitin in addition to other materials. It usually forms perpendicular to the long axis of a cell or hypha and grows centripetally from the cell wall to the center of the cell and often functions in the compartmentalization of a cell into two daughter cells.
2 Q00647 (/IDA) Q2US45 (/IDA)
Actin cortical patch GO:0030479
An endocytic patch that consists of an actin-containing structure found at the plasma membrane in cells; formed of networks of branched actin filaments that lie just beneath the plasma membrane and assemble, move, and disassemble rapidly. An example of this is the actin cortical patch found in Saccharomyces cerevisiae.
2 P36006 (/TAS) P36006 (/TAS)
Cell periphery GO:0071944
The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures.
2 P36006 (/HDA) P36006 (/HDA)
Hyphal tip GO:0001411
The end, or tip, of a fungal hypha, where polarized growth occurs during hyphal elongation.
1 Q59MQ0 (/IMP)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q2US45 (/IDA)
Cellular bud tip GO:0005934
The end of a cellular bud distal to the site of attachment to the mother cell.
1 Q59MQ0 (/IDA)
Cellular bud neck GO:0005935
The constriction between the mother cell and daughter cell (bud) in an organism that reproduces by budding.
1 Q59MQ0 (/IDA)
Mating projection tip GO:0043332
The apex of the mating projection in unicellular fungi exposed to mating pheromone; site of polarized growth.
1 Q59MQ0 (/IDA)