CATH Superfamily 2.30.29.30
Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
".
FunFam 455: Psy2p
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | P40164 (/IPI) P40164 (/IPI) |
|
Protein phosphatase regulator activity GO:0019888
Modulates the activity of a protein phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a protein substrate molecule.
|
2 | P40164 (/IDA) P40164 (/IDA) |
|
Protein phosphatase activator activity GO:0072542
Increases the activity of a protein phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a protein substrate molecule.
|
1 | Q9Y7J8 (/EXP) |
There are 10 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein dephosphorylation GO:0006470
The process of removing one or more phosphoric residues from a protein.
|
3 | A0A1D8PCN8 (/IMP) P40164 (/IMP) P40164 (/IMP) |
|
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
|
2 | P40164 (/IGI) P40164 (/IGI) |
|
Signal transduction involved in meiotic recombination checkpoint GO:0072462
A signal transduction process that contributes to a meiotic recombination checkpoint.
|
2 | P40164 (/IMP) P40164 (/IMP) |
|
Negative regulation of glucose mediated signaling pathway GO:1902660
Any process that stops, prevents or reduces the frequency, rate or extent of glucose mediated signaling pathway.
|
2 | P40164 (/IMP) P40164 (/IMP) |
|
Negative regulation of DNA damage checkpoint GO:2000002
Any process that stops, prevents, or reduces the frequency, rate or extent of a DNA damage checkpoint.
|
2 | P40164 (/IMP) P40164 (/IMP) |
|
Positive regulation of double-strand break repair via nonhomologous end joining GO:2001034
Any process that activates or increases the frequency, rate or extent of double-strand break repair via nonhomologous end joining.
|
2 | P40164 (/IMP) P40164 (/IMP) |
|
Regulation of DNA repair GO:0006282
Any process that modulates the frequency, rate or extent of DNA repair.
|
1 | Q9Y7J8 (/ISO) |
|
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
|
1 | A0A1D8PCN8 (/IMP) |
|
Negative regulation of sister chromatid cohesion GO:0045875
Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid cohesion.
|
1 | Q9Y7J8 (/EXP) |
|
Negative regulation of sister chromatid cohesion GO:0045875
Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid cohesion.
|
1 | Q9Y7J8 (/IC) |
There are 6 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
3 | P40164 (/HDA) P40164 (/HDA) Q9Y7J8 (/HDA) |
|
Protein phosphatase 4 complex GO:0030289
A protein serine/threonine phosphatase complex formed by the catalytic subunit of protein phosphatase 4 plus one or more regulatory subunits.
|
2 | P40164 (/IDA) P40164 (/IDA) |
|
Protein phosphatase 4 complex GO:0030289
A protein serine/threonine phosphatase complex formed by the catalytic subunit of protein phosphatase 4 plus one or more regulatory subunits.
|
2 | P40164 (/IMP) P40164 (/IMP) |
|
Nuclear chromatin GO:0000790
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.
|
1 | Q9Y7J8 (/EXP) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | Q580Q3 (/IDA) |
|
Protein phosphatase 4 complex GO:0030289
A protein serine/threonine phosphatase complex formed by the catalytic subunit of protein phosphatase 4 plus one or more regulatory subunits.
|
1 | Q9Y7J8 (/ISO) |