The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Catalase HPII

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 9 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Catalase activity GO:0004096
Catalysis of the reaction: 2 hydrogen peroxide = O2 + 2 H2O.
23 A2Q7T0 (/IMP) A2Q7T0 (/IMP) P21179 (/IMP) P21179 (/IMP) P21179 (/IMP) P21179 (/IMP) P21179 (/IMP) P21179 (/IMP) P55305 (/IMP) Q2U962 (/IMP)
(13 more)
Catalase activity GO:0004096
Catalysis of the reaction: 2 hydrogen peroxide = O2 + 2 H2O.
11 P21179 (/IDA) P21179 (/IDA) P21179 (/IDA) P21179 (/IDA) P21179 (/IDA) P21179 (/IDA) Q55DH8 (/IDA) Q92405 (/IDA) Q92405 (/IDA) Q92405 (/IDA)
(1 more)
Heme binding GO:0020037
Interacting selectively and non-covalently with heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.
7 P21179 (/IDA) P21179 (/IDA) P21179 (/IDA) P21179 (/IDA) P21179 (/IDA) P21179 (/IDA) Q9C168 (/IDA)
Iron ion binding GO:0005506
Interacting selectively and non-covalently with iron (Fe) ions.
6 P21179 (/IDA) P21179 (/IDA) P21179 (/IDA) P21179 (/IDA) P21179 (/IDA) P21179 (/IDA)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
6 P21179 (/IDA) P21179 (/IDA) P21179 (/IDA) P21179 (/IDA) P21179 (/IDA) P21179 (/IDA)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
6 P21179 (/IPI) P21179 (/IPI) P21179 (/IPI) P21179 (/IPI) P21179 (/IPI) P21179 (/IPI)
Catalase activity GO:0004096
Catalysis of the reaction: 2 hydrogen peroxide = O2 + 2 H2O.
2 Q87UN3 (/ISS) Q87UN3 (/ISS)
Catalase activity GO:0004096
Catalysis of the reaction: 2 hydrogen peroxide = O2 + 2 H2O.
1 P55305 (/RCA)
Catechol oxidase activity GO:0004097
Catalysis of the reaction: 2 catechol + O2 = 2 1,2-benzoquinone + 2 H2O.
1 M4GGR6 (/IDA)

There are 14 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cellular response to hydrogen peroxide GO:0070301
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.
15 P55305 (/IMP) Q2U962 (/IMP) Q2U962 (/IMP) Q2U962 (/IMP) Q2U962 (/IMP) Q2U962 (/IMP) Q2U962 (/IMP) Q877A8 (/IMP) Q877A8 (/IMP) Q877A8 (/IMP)
(5 more)
Hyperosmotic response GO:0006972
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hyperosmotic environment, i.e. an environment with a higher concentration of solutes than the organism or cell.
6 P21179 (/IEP) P21179 (/IEP) P21179 (/IEP) P21179 (/IEP) P21179 (/IEP) P21179 (/IEP)
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
6 P21179 (/IEP) P21179 (/IEP) P21179 (/IEP) P21179 (/IEP) P21179 (/IEP) P21179 (/IEP)
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
6 P21179 (/IMP) P21179 (/IMP) P21179 (/IMP) P21179 (/IMP) P21179 (/IMP) P21179 (/IMP)
Hydrogen peroxide catabolic process GO:0042744
The chemical reactions and pathways resulting in the breakdown of hydrogen peroxide (H2O2).
6 P21179 (/IMP) P21179 (/IMP) P21179 (/IMP) P21179 (/IMP) P21179 (/IMP) P21179 (/IMP)
Cellular response to iron ion starvation GO:0010106
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of iron ions.
4 P55305 (/IEP) Q92405 (/IEP) Q92405 (/IEP) Q92405 (/IEP)
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
2 Q87UN3 (/ISS) Q87UN3 (/ISS)
Response to reactive oxygen species GO:0000302
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.
1 Q55DH8 (/IMP)
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
1 Q9C168 (/TAS)
D-gluconate metabolic process GO:0019521
The chemical reactions and pathways involving D-gluconate, the anion of D-gluconic acid, the aldonic acid derived from glucose.
1 P55305 (/RCA)
Sorocarp development GO:0030587
The process whose specific outcome is the progression of the sorocarp over time, from its formation to the mature structure. The process begins with the aggregation of individual cells and ends with the mature sorocarp. The sorocarp is a structure containing a spore-bearing sorus that sits on top of a stalk. An example of this process is found in Dictyostelium discoideum.
1 Q55DH8 (/IMP)
Cellular response to heat GO:0034605
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
1 P55305 (/IMP)
Hydrogen peroxide catabolic process GO:0042744
The chemical reactions and pathways resulting in the breakdown of hydrogen peroxide (H2O2).
1 Q55DH8 (/IDA)
Conidium formation GO:0048315
The process of producing non-motile spores, called conidia, via mitotic asexual reproduction in higher fungi. Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus.
1 Q9C168 (/IDA)

There are 7 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
6 P21179 (/IDA) P21179 (/IDA) P21179 (/IDA) P21179 (/IDA) P21179 (/IDA) P21179 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
6 P21179 (/HDA) P21179 (/HDA) P21179 (/HDA) P21179 (/HDA) P21179 (/HDA) P21179 (/HDA)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
5 Q877A8 (/IDA) Q877A8 (/IDA) Q877A8 (/IDA) Q877A8 (/IDA) Q877A8 (/IDA)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
3 Q92405 (/IDA) Q92405 (/IDA) Q92405 (/IDA)
Peroxisome GO:0005777
A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.
2 A2Q7T0 (/IDA) A2Q7T0 (/IDA)
Ascospore wall GO:0005619
The specialized cell wall of the ascospore (spore), which is the product of meiotic division. Examples of this component are found in Fungi.
1 Q9C168 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q55DH8 (/IDA)