The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Catalase, four-helical domain

Catalases are antioxidant enzymes that catalyse the conversion of hydrogen peroxide to water and molecular oxygen, serving to protect cells from its toxic effects PMID:11351128. Most catalases are mono-functional, haem-containing enzymes, although there are also bifunctional haem-containing peroxidase/catalases that are closely related to plant peroxidases, and non-haem, manganese-containing catalases that are found in bacteria PMID:14745498. They are composed of a long amino-terminal arm, an antiparallel eight-stranded beta-barrel, an extended wrapping loop, a four-helical domain and, in large catalases, a carboxy-terminal domain with flavodoxin-like topology joined by a long loop PMID:23519415. This entry represents the helical domain of catalases.

PMID:11351128 PMID:14745498 PMID:23519415

GO Diversity

Unique GO annotations
22 Unique GO terms

EC Diversity

Unique EC annotations
1 Unique EC terms

Species Diversity

Unique species annotations
3087 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Domains: 279
Domain clusters (>95% seq id): 5
Domain clusters (>35% seq id): 3
Unique PDBs: 71
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 1
Unique EC: 1
Unique GO: 22
Unique Species: 3087