CATH Superfamily 1.10.8.60
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 231: Origin recognition complex subunit 5
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
DNA replication origin binding GO:0003688
Interacting selectively and non-covalently with the DNA replication origin, a unique DNA sequence of a replicon at which DNA replication is initiated and proceeds bidirectionally or unidirectionally.
|
4 | P50874 (/IDA) P50874 (/IDA) P50874 (/IDA) P50874 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
4 | P50874 (/IPI) P50874 (/IPI) P50874 (/IPI) P50874 (/IPI) |
|
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
4 | P50874 (/IMP) P50874 (/IMP) P50874 (/IMP) P50874 (/IMP) |
There are 5 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Pre-replicative complex assembly involved in nuclear cell cycle DNA replication GO:0006267
The aggregation, arrangement and bonding together of a set of components to form the nuclear pre-replicative complex, a protein-DNA complex that forms at the eukaryotic DNA replication origin and is required for replication initiation.
|
4 | P50874 (/IDA) P50874 (/IDA) P50874 (/IDA) P50874 (/IDA) |
|
DNA replication initiation GO:0006270
The process in which DNA-dependent DNA replication is started; this begins with the ATP dependent loading of an initiator complex onto the DNA, this is followed by DNA melting and helicase activity. In bacteria, the gene products that enable the helicase activity are loaded after the initial melting and in archaea and eukaryotes, the gene products that enable the helicase activity are inactive when they are loaded and subsequently activate.
|
4 | P50874 (/IGI) P50874 (/IGI) P50874 (/IGI) P50874 (/IGI) |
|
DNA replication initiation GO:0006270
The process in which DNA-dependent DNA replication is started; this begins with the ATP dependent loading of an initiator complex onto the DNA, this is followed by DNA melting and helicase activity. In bacteria, the gene products that enable the helicase activity are loaded after the initial melting and in archaea and eukaryotes, the gene products that enable the helicase activity are inactive when they are loaded and subsequently activate.
|
4 | P50874 (/IMP) P50874 (/IMP) P50874 (/IMP) P50874 (/IMP) |
|
Chromatin silencing at silent mating-type cassette GO:0030466
Repression of transcription at silent mating-type loci by alteration of the structure of chromatin.
|
4 | P50874 (/IDA) P50874 (/IDA) P50874 (/IDA) P50874 (/IDA) |
|
Regulation of chromatin silencing at telomere GO:0031938
Any process that affects the rate, extent or location of chromatin silencing at telomeres.
|
4 | P50874 (/IMP) P50874 (/IMP) P50874 (/IMP) P50874 (/IMP) |
There are 4 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nuclear pre-replicative complex GO:0005656
A protein-DNA complex assembled at eukaryotic DNA replication origins during late mitosis and G1, allowing the origin to become competent, or 'licensed', for replication. The complex normally includes the origin recognition complex (ORC), Cdc6, Cdt1 and the MiniChromosome Maintenance (Mcm2-7) proteins.
|
4 | P50874 (/IDA) P50874 (/IDA) P50874 (/IDA) P50874 (/IDA) |
|
Nuclear origin of replication recognition complex GO:0005664
A multisubunit complex that is located at the replication origins of a chromosome in the nucleus.
|
4 | P50874 (/IDA) P50874 (/IDA) P50874 (/IDA) P50874 (/IDA) |
|
Nuclear origin of replication recognition complex GO:0005664
A multisubunit complex that is located at the replication origins of a chromosome in the nucleus.
|
4 | P50874 (/IMP) P50874 (/IMP) P50874 (/IMP) P50874 (/IMP) |
|
DNA replication preinitiation complex GO:0031261
A protein-DNA complex assembled at eukaryotic DNA replication origins immediately prior to the initiation of DNA replication. The preinitiation complex is formed by the assembly of additional proteins onto an existing prereplicative complex. In budding yeast, the additional proteins might include Cdc45p, Sld2p, Sld3p, Dpb11p, DNA polymerases, and others; in fission yeast the GINS complex is present.
|
4 | P50874 (/IDA) P50874 (/IDA) P50874 (/IDA) P50874 (/IDA) |