The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
2784
3D
1lv7A02 - 99.2
2
1890
3D
4i81F02 - 98.4
3
1746 - - 93.8
4
1580
3D
3cf2D04 - 83.0
5
1217
3D
4a3vD01 - 96.9
6
1109
3D
5m32h03 - 96.0
7
1009 - - 94.1
8
920 - - 96.6
10
911
3D
3uk6L02 - 99.0
9
910
3D
3whlG02 - 92.9
11
899
3D
1r6bX03 - 86.6
13
823
3D
3gliI02 - 81.6
12
799
3D
1sxjB02 - 83.2
14
722
3D
4lzzX02 - 95.5
15
611
3D
6ap1F02 - 96.0
16
569 - - 96.5
17
551
3D
4ljaA02 - 98.7
18
533
3D
2dvwB00 - 86.0
19
507 - - 98.0
20
457
3D
2dzoD00 - 73.0
21
431
3D
1sxjA02 - 96.6
22
418
3D
3d8bB02 - 98.7
27
378
3D
5ji3F03 - 82.5
24
354
3D
3sc3B02 - 79.6
23
353 - - 73.4
25
335
3D
6b5cA02 - 88.5
26
327 - - 86.6
28
312
3D
1sxjC02 - 97.8
29
285 - - 89.3
30
279 - - 96.8
31
235
3D
6mdpF02 - 88.2
32
224
3D
1sxjD02 - 96.6
33
205
3D
2qz4A02 - 81.1
35
197
3D
1qzmA00 - 76.3
34
196 - - 23.7
37
190
3D
5exxA02 - 36.7
36
189
3D
3vfdA02 - 76.8
38
177 - - 97.6
41
167
3D
3gliF02 - 59.7
39
162 - - 96.1
40
158 - - 45.7
42
153
3D
4jn6C02 - 68.5
43
139 - - 84.1
44
131 - - 33.6
45
129 - - 93.1
46
123 - - 46.6
47
118 - - 0.0
50
116
3D
4qosA02 - 48.6
48
110 - - 86.3
49
106 - - 58.8
51
99 - - 46.9
52
95 - - 81.1
53
94
3D
2v6zM00 - 98.6
54
93 - - 84.5
55
89 - - 56.6
56
87 - - 64.1
57
86 - - 93.5
58
84 - - 88.0
59
81 - - 83.9
60
80 - - 92.5
62
79 - - 92.8
61
79 - - 86.8
63
78 - - 75.2
64
76 - - 92.6
70
73
3D
3u61E02 - 13.1
65
66 - - 0.0
67
65 - - 82.7
66
65 - - 83.2
73
62
3D
2qbyA01 - 94.7
69
61 - - 91.8
68
61 - - 68.3
71
59 - - 85.9
72
58 - - 51.9
74
57 - - 89.8
75
57 - - 82.5
76
54 - - 35.5
77
54 - - 73.5
78
53 - - 71.2
79
53 - - 78.5
80
53 - - 72.5
82
52 - - 71.2
81
52 - - 88.9
83
51 - - 96.0
84
49 - - 89.4
85
48 - - 61.3
87
47 - - 3.5
86
47 - - 34.2
89
45 - - 63.6
88
45 - - 24.8
90
44 - - 17.7
91
44 - - 91.6
92
43 - - 64.6
93
40 - - 77.1
94
39 - - 78.2
95
39 - - 51.0
96
38 - - 72.5
97
38 - - 96.9
101
37 - - 74.6
98
37 - - 9.7
100
37 - - 35.4
99
37 - - 48.0
102
36 - - 71.7
103
34 - - 12.3
104
33 - - 66.9
105
32 - - 92.6
106
31 - - 74.6
107
30 - - 22.9
109
30 - - 82.6
108
30 - - 96.8
120
29
3D
5ep4A02 - 95.2
110
29 - - 93.3
112
29 - - 92.8
111
29 - - 36.2
113
28 - - 83.6
114
26 - - 43.7
115
26 - - 94.7
118
25 - - 13.7
119
25 - - 12.2
116
25 - - 88.3
117
25 - - 40.9
122
24 - - 50.4
121
24 - - 18.5
123
24 - - 64.5
127
22 - - 91.9
124
22 - - 1.9
126
22 - - 83.1
125
22 - - 62.5
129
21 - - 7.8
128
21 - - 72.4
130
21 - - 2.1
131
21 - - 12.1
247
21
3D
4qhtG02 - 6.9
132
20 - - 85.4
133
20 - - 89.9
139
19 - - 54.9
135
19 - - 4.1
136
19 - - 21.3
138
19 - - 90.1
137
19 - - 43.1
134
19 - - 5.1
145
18 - - 11.6
144
18 - - 17.0
142
18 - - 95.0
140
18 - - 1.2
143
18 - - 73.6
147
18 - - 78.4
141
18 - - 0.0
146
18 - - 72.6
153
17 - - 72.5
152
17 - - 4.5
151
17 - - 57.2
150
17 - - 12.6
155
17 - - 67.6
154
17 - - 11.5
148
17 - - 27.7
149
17 - - 73.7
160
16 - - 89.2
159
16 - - 93.8
158
16 - - 76.2
313
16
3D
4lgmA02 - 66.4
157
16 - - 70.9
156
16 - - 78.1
161
15 - - 94.9
163
15 - - 6.1
162
15 - - 4.2
165
15 - - 72.1
164
15 - - 1.2
168
14 - - 10.1
171
14 - - 79.6
170
14 - - 79.6
167
14 - - 0.0
169
14 - - 70.6
172
14
3D
2x8aA02 - 60.3
166
14 - - 13.9
178
13 - - 94.9
177
13 - - 0.0
176
13 - - 22.1
175
13 - - 19.8
174
13 - - 52.1
214
13
3D
3sylB02 - 79.7
173
13 - - 87.1
180
12 - - 9.0
182
12 - - 16.2
184
12 - - 50.3
181
12 - - 0.0
183
12 - - 35.6
186
12 - - 84.9
179
12 - - 51.4
185
12 - - 85.7
194
11 - - 0.0
193
11 - - 0.0
189
11 - - 90.8
191
11 - - 72.8
187
11 - - 19.9
192
11 - - 7.7
195
11 - - 96.5
188
11 - - 15.1
190
11 - - 34.3
204
11
3D
1sxjE02 - 0.0
196
11 - - 10.7
206
10 - - 48.5
211
10 - - 91.8
205
10 - - 35.0
200
10 - - 1.7
197
10 - - 77.5
207
10 - - 41.0
208
10 - - 10.8
199
10 - - 95.3
198
10 - - 74.8
202
10 - - 55.9
201
10 - - 92.8
203
10 - - 13.8
209
10 - - 79.5
210
10 - - 76.3
220
9 - - 23.5
218
9 - - 1.7
221
9 - - 54.3
213
9 - - 7.0
212
9 - - 0.0
215
9 - - 73.2
222
9 - - 85.6
217
9 - - 11.5
216
9 - - 59.1
219
9 - - 68.4
226
8 - - 17.7
224
8 - - 34.4
227
8 - - 16.0
232
8 - - 82.9
225
8 - - 10.3
233
8 - - 70.7
230
8 - - 11.6
229
8 - - 15.5
231
8 - - 0.0
228
8 - - 0.0
223
8 - - 0.0
236
7 - - 6.0
234
7 - - 1.8
244
7 - - 13.6
246
7 - - 0.0
237
7 - - 0.0
254
7 - - 1.0
235
7 - - 5.4
349
7
3D
2z4sA02 - 12.0
251
7 - - 8.0
256
7 - - 75.1
255
7 - - 0.0
250
7 - - 0.0
245
7 - - 0.0
257
7 - - 90.6
241
7 - - 8.8
249
7 - - 7.5
240
7 - - 1.4
239
7 - - 18.6
269
7
3D
1um8A02 - 9.0
243
7 - - 7.5
238
7 - - 5.6
253
7 - - 86.3
258
7 - - 84.3
252
7 - - 7.7
248
7 - - 0.0
242
7 - - 4.1
260
6 - - 1.8
265
6 - - 22.7
272
6 - - 12.0
275
6 - - 31.7
262
6 - - 7.0
279
6 - - 71.8
264
6 - - 3.4
263
6 - - 13.1
274
6 - - 42.2
278
6 - - 73.6
267
6 - - 14.4
276
6 - - 9.3
259
6 - - 11.1
273
6 - - 6.7
270
6 - - 10.0
266
6 - - 46.4
261
6 - - 11.1
268
PAS1/Peroxin-1
6 - - 39.5
277
6 - - 16.5
271
6 - - 33.6
285
5 - - 7.5
288
5 - - 14.2
295
5 - - 69.4
286
5 - - 58.1
296
5 - - 76.5
287
AAA
5 - - 9.9
294
5 - - 10.1
293
5 - - 4.4
292
5 - - 8.4
291
5 - - 15.3
280
5 - - 72.5
361
5
3D
3h4mC02 - 4.7
281
5 - - 3.4
284
5 - - 13.4
289
5 - - 0.0
319
5
3D
2qbyB01 - 19.2
282
5 - - 1.6
297
5 - - 73.0
290
5 - - 3.9
283
5 - - 0.0
325
4 - - 69.1
311
4 - - 36.9
324
4 - - 70.2
312
AAA
4 - - 0.0
309
4 - - 6.0
300
4 - - 73.0
308
4 - - 2.5
301
4 - - 90.2
323
CDC48 homologue
4 - - 76.7
322
4 - - 29.3
310
4 - - 85.8
303
4 - - 5.4
316
4 - - 8.3
320
HSP100
4 - - 0.0
314
4 - - 49.0
307
4 - - 9.7
326
4 - - 69.1
299
4 - - 8.8
302
4 - - 0.0
315
4 - - 41.6
305
4 - - 6.7
317
4 - - 0.0
298
4 - - 5.9
321
4 - - 4.9
304
4 - - 6.4
306
4 - - 6.0
318
4 - - 7.3
331
3 - - 0.0
350
3 - - 61.2
337
3 - - 0.0
340
3 - - 0.0
348
3 - - 9.6
351
3 - - 37.4
342
3 - - 0.0
341
3 - - 12.0
329
3 - - 70.4
346
3 - - 0.0
333
3 - - 0.0
352
3 - - 72.0
330
3 - - 70.3
353
3 - - 12.7
354
3 - - 64.6
332
3 - - 0.0
347
3 - - 0.0
327
MGS1
3 - - 10.0
355
3 - - 55.5
335
3 - - 21.6
334
3 - - 24.1
338
3 - - 7.4
328
3 - - 78.0
343
3 - - 0.0
339
3 - - 34.9
345
3 - - 7.8
344
3 - - 5.7
336
3 - - 0.0
443
2 - - 0.0
358
2 - - 41.3
437
2 - - 0.0
458
Eurofung
2 - - 40.0
451
2 - - 0.0
454
2 - - 19.0
378
2 - - 28.6
431
2 - - 0.0
382
2 - - 8.2
389
2 - - 1.6
418
2 - - 0.0
388
2 - - 5.4
364
2 - - 30.8
367
2 - - 1.4
391
2 - - 0.0
460
2 - - 49.6
453
2 - - 0.0
410
2 - - 13.9
430
2 - - 1.0
447
2 - - 12.0
379
2 - - 41.7
415
2 - - 48.9
452
2 - - 2.7
438
2 - - 0.0
444
2 - - 0.0
417
2 - - 0.0
405
2 - - 13.4
370
2 - - 0.0
416
2 - - 14.7
380
2 - - 41.8
381
2 - - 45.1
392
2 - - 0.0
373
2 - - 8.4
399
2 - - 0.0
436
2 - - 0.8
456
2 - - 35.6
386
2 - - 2.9
445
2 - - 0.0
366
2 - - 5.1
400
2 - - 2.2
441
2 - - 0.0
413
2 - - 0.0
432
2 - - 9.7
427
2 - - 0.0
446
2 - - 0.0
426
2 - - 12.1
369
2 - - 0.0
372
2 - - 10.2
428
2 - - 0.0
359
2 - - 0.0
414
2 - - 0.0
394
2 - - 0.0
360
2 - - 0.0
393
2 - - 0.0
449
2 - - 0.0
375
2 - - 3.4
387
2 - - 0.0
461
2 - - 42.3
425
2 - - 0.0
368
2 - - 0.0
424
2 - - 9.2
395
2 - - 1.2
434
2 - - 7.6
374
2 - - 0.0
442
2 - - 1.8
429
2 - - 0.0
409
2 - - 2.7
412
2 - - 2.4
385
2 - - 3.8
433
2 - - 0.0
440
2 - - 0.0
377
2 - - 1.5
423
2 - - 0.0
422
2 - - 0.0
402
2 - - 3.5
363
2 - - 43.2
362
2 - - 0.0
439
2 - - 0.0
411
2 - - 0.0
398
2 - - 0.0
384
2 - - 4.6
407
2 - - 0.0
376
CDC48 subfamily
2 - - 0.0
397
2 - - 0.0
459
2 - - 41.8
371
2 - - 1.9
435
2 - - 0.0
401
2 - - 0.0
404
2 - - 0.0
420
2 - - 4.7
448
2 - - 0.0
357
2 - - 0.0
455
2 - - 38.0
457
2 - - 34.9
383
2 - - 7.3
550
2
3D
1l8qA02 - 0.0
419
2 - - 10.6
406
2 - - 1.2
396
2 - - 0.0
365
2 - - 0.0
403
2 - - 0.0
421
Fragment
2 - - 0.0
450
2 - - 21.5
390
AAA
2 - - 0.0
408
2 - - 29.3
356
2 - - 0.0
559
1 - - 0.0
560
1 - - 0.0
580
1 - - 0.0
512
1 - - 0.0
463
1 - - 0.0
517
1 - - 0.0
578
1 - - 0.0
572
1 - - 0.0
540
1 - - 0.0
527
1 - - 0.0
571
1 - - 0.0
495
1 - - 0.0
548
1 - - 0.0
594
1 - - 0.0
486
1 - - 0.0
509
1 - - 0.0
569
1 - - 0.0
485
1 - - 0.0
523
1 - - 0.0
586
1 - - 0.0
595
1 - - 0.0
488
1 - - 0.0
536
1 - - 0.0
579
1 - - 0.0
480
1 - - 0.0
535
1 - - 0.0
508
1 - - 0.0
541
1 - - 0.0
558
1 - - 0.0
507
1 - - 0.0
573
1 - - 0.0
567
1 - - 0.0
506
1 - - 0.0
581
1 - - 0.0
496
1 - - 0.0
568
1 - - 0.0
493
1 - - 0.0
525
1 - - 0.0
582
1 - - 0.0
534
1 - - 0.0
557
1 - - 0.0
468
1 - - 0.0
475
1 - - 0.0
515
1 - - 0.0
519
1 - - 0.0
590
1 - - 0.0
545
1 - - 0.0
588
1 - - 0.0
542
1 - - 0.0
498
1 - - 0.0
483
1 - - 0.0
574
1 - - 0.0
566
1 - - 0.0
526
1 - - 0.0
500
1 - - 0.0
533
1 - - 0.0
556
1 - - 0.0
462
1 - - 0.0
477
1 - - 0.0
514
1 - - 0.0
513
1 - - 0.0
476
1 - - 0.0
510
1 - - 0.0
549
1 - - 0.0
469
1 - - 0.0
575
1 - - 0.0
589
1 - - 0.0
501
1 - - 0.0
490
1 - - 0.0
543
1 - - 0.0
583
1 - - 0.0
591
1 - - 0.0
539
1 - - 0.0
565
1 - - 0.0
520
1 - - 0.0
532
1 - - 0.0
584
1 - - 0.0
492
1 - - 0.0
511
1 - - 0.0
489
1 - - 0.0
585
1 - - 0.0
471
1 - - 0.0
465
1 - - 0.0
502
1 - - 0.0
479
1 - - 0.0
553
1 - - 0.0
555
1 - - 0.0
538
1 - - 0.0
524
1 - - 0.0
554
1 - - 0.0
552
1 - - 0.0
521
1 - - 0.0
598
1 - - 0.0
467
1 - - 0.0
481
1 - - 0.0
474
1 - - 0.0
564
1 - - 0.0
563
1 - - 0.0
503
1 - - 0.0
593
1 - - 0.0
576
1 - - 0.0
484
1 - - 0.0
544
1 - - 0.0
464
1 - - 0.0
562
1 - - 0.0
518
1 - - 0.0
497
1 - - 0.0
472
1 - - 0.0
478
1 - - 0.0
546
1 - - 0.0
537
1 - - 0.0
522
1 - - 0.0
599
1 - - 0.0
587
1 - - 0.0
551
1 - - 0.0
529
1 - - 0.0
504
1 - - 0.0
531
1 - - 0.0
596
1 - - 0.0
516
1 - - 0.0
494
1 - - 0.0
487
1 - - 0.0
577
1 - - 0.0
561
1 - - 0.0
600
1 - - 0.0
505
1 - - 0.0
592
1 - - 0.0
547
1 - - 0.0
482
1 - - 0.0
499
1 - - 0.0
530
1 - - 0.0
470
1 - - 0.0
570
1 - - 0.0
466
1 - - 0.0
491
1 - - 0.0
473
1 - - 0.0
597
1 - - 0.0
528
1 - - 0.0