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CATH Superfamily 1.10.420.10

Peroxidase, domain 2

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Peroxidase, domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 4: Catalase-peroxidase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Catalase peroxidase. [EC: 1.11.1.21]
(1) Donor + H(2)O(2) = oxidized donor + 2 H(2)O. (2) 2 H(2)O(2) = O(2) + 2 H(2)O.
  • Differs from EC 1.11.1.7, peroxidase, in having a relatively high catalase (EC 1.11.1.6) activity with H(2)O(2) as donor, releasing O(2); both activities use the same heme active site.
  • In Mycobacterium tuberculosis it is responsible for activation of the commonly used antitubercular drug, isoniazid.
 7175 A0A023Z5R4 A0A023Z5R4 A0A023Z5R4 A0A023Z5R4 A0A023Z5R4 A0A023Z5R4 A0A023Z5R4 A0A023Z5R4 A0A023Z5R4 A0A023Z5R4
(7165 more...)