The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"High mobility group box domain
".
FunFam 17: high mobility group protein B3
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 11 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Four-way junction DNA binding GO:0000400
Interacting selectively and non-covalently with DNA containing four-way junctions, also known as Holliday junctions, a structure where two DNA double strands are held together by reciprocal exchange of two of the four strands, one strand each from the two original helices.
|
1123 |
A0A087QUH1 (/ISS)
A0A087QUH1 (/ISS)
A0A087QUH1 (/ISS)
A0A087QUH1 (/ISS)
A0A087QUH1 (/ISS)
A0A087QUH1 (/ISS)
A0A087QUH1 (/ISS)
A0A087QUH1 (/ISS)
A0A087QUH1 (/ISS)
A0A087QUH1 (/ISS)
(1113 more) |
|
DNA binding, bending GO:0008301
The activity of binding selectively and non-covalently to and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence.
|
1121 |
A0A087QUH1 (/ISS)
A0A087QUH1 (/ISS)
A0A087QUH1 (/ISS)
A0A087QUH1 (/ISS)
A0A087QUH1 (/ISS)
A0A087QUH1 (/ISS)
A0A087QUH1 (/ISS)
A0A087QUH1 (/ISS)
A0A087QUH1 (/ISS)
A0A087QUH1 (/ISS)
(1111 more) |
|
DNA binding, bending GO:0008301
The activity of binding selectively and non-covalently to and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence.
|
70 |
A0A0A0MQ46 (/IDA)
A0A0A0MQ46 (/IDA)
A0A0A0MQ46 (/IDA)
A0A0A0MQ46 (/IDA)
A0A0A0MQ46 (/IDA)
A0A0A0MQ46 (/IDA)
A0A0A0MQ46 (/IDA)
A0A0A0MQ46 (/IDA)
A0A0A0MQ46 (/IDA)
A0A0A0MQ46 (/IDA)
(60 more) |
|
Four-way junction DNA binding GO:0000400
Interacting selectively and non-covalently with DNA containing four-way junctions, also known as Holliday junctions, a structure where two DNA double strands are held together by reciprocal exchange of two of the four strands, one strand each from the two original helices.
|
68 |
A0A0A0MQ46 (/IDA)
A0A0A0MQ46 (/IDA)
A0A0A0MQ46 (/IDA)
A0A0A0MQ46 (/IDA)
A0A0A0MQ46 (/IDA)
A0A0A0MQ46 (/IDA)
A0A0A0MQ46 (/IDA)
A0A0A0MQ46 (/IDA)
A0A0A0MQ46 (/IDA)
A0A0A0MQ46 (/IDA)
(58 more) |
|
Double-stranded DNA binding GO:0003690
Interacting selectively and non-covalently with double-stranded DNA.
|
6 | O15347 (/ISS) O15347 (/ISS) O15347 (/ISS) O15347 (/ISS) O15347 (/ISS) O15347 (/ISS) |
|
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
6 | O15347 (/HDA) O15347 (/HDA) O15347 (/HDA) O15347 (/HDA) O15347 (/HDA) O15347 (/HDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
6 | O15347 (/IPI) O15347 (/IPI) O15347 (/IPI) O15347 (/IPI) O15347 (/IPI) O15347 (/IPI) |
|
DNA binding, bending GO:0008301
The activity of binding selectively and non-covalently to and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence.
|
6 | O15347 (/TAS) O15347 (/TAS) O15347 (/TAS) O15347 (/TAS) O15347 (/TAS) O15347 (/TAS) |
|
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
2 | O54879 (/IDA) O54879 (/IDA) |
|
Double-stranded DNA binding GO:0003690
Interacting selectively and non-covalently with double-stranded DNA.
|
2 | Q32L31 (/IDA) Q32L31 (/IDA) |
|
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
2 | O54879 (/IDA) O54879 (/IDA) |
There are 7 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
DNA geometric change GO:0032392
The process in which a transformation is induced in the geometry of a DNA double helix, resulting in a change in twist, writhe, or both, but with no change in linking number. Includes the unwinding of double-stranded DNA by helicases.
|
1123 |
A0A087QUH1 (/ISS)
A0A087QUH1 (/ISS)
A0A087QUH1 (/ISS)
A0A087QUH1 (/ISS)
A0A087QUH1 (/ISS)
A0A087QUH1 (/ISS)
A0A087QUH1 (/ISS)
A0A087QUH1 (/ISS)
A0A087QUH1 (/ISS)
A0A087QUH1 (/ISS)
(1113 more) |
|
DNA geometric change GO:0032392
The process in which a transformation is induced in the geometry of a DNA double helix, resulting in a change in twist, writhe, or both, but with no change in linking number. Includes the unwinding of double-stranded DNA by helicases.
|
68 |
A0A0A0MQ46 (/IDA)
A0A0A0MQ46 (/IDA)
A0A0A0MQ46 (/IDA)
A0A0A0MQ46 (/IDA)
A0A0A0MQ46 (/IDA)
A0A0A0MQ46 (/IDA)
A0A0A0MQ46 (/IDA)
A0A0A0MQ46 (/IDA)
A0A0A0MQ46 (/IDA)
A0A0A0MQ46 (/IDA)
(58 more) |
|
DNA recombination GO:0006310
Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction.
|
6 | O15347 (/ISS) O15347 (/ISS) O15347 (/ISS) O15347 (/ISS) O15347 (/ISS) O15347 (/ISS) |
|
Multicellular organism development GO:0007275
The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
|
6 | O15347 (/TAS) O15347 (/TAS) O15347 (/TAS) O15347 (/TAS) O15347 (/TAS) O15347 (/TAS) |
|
DNA recombination GO:0006310
Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction.
|
2 | Q32L31 (/IDA) Q32L31 (/IDA) |
|
Negative regulation of B cell differentiation GO:0045578
Any process that stops, prevents, or reduces the frequency, rate or extent of B cell differentiation.
|
2 | O54879 (/IDA) O54879 (/IDA) |
|
Negative regulation of myeloid cell differentiation GO:0045638
Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid cell differentiation.
|
2 | O54879 (/IDA) O54879 (/IDA) |
There are 1 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
2 | O54879 (/IDA) O54879 (/IDA) |