The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
High mobility group box domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
1842
3D
2lefA00 - 70.9
2
1466
3D
2gzkA01 - 96.7
3
1270
3D
1i11A00 - 93.8
4
759 - - 74.7
5
662
3D
2co9A00 - 81.0
6
565
3D
2yrqA01 - 93.6
7
515
3D
3u2bC00 - 77.2
8
446
3D
3f27D00 - 74.8
9
440
3D
2yukA00 - 91.1
10
401 - - 58.6
11
335 - - 70.4
12
311 - - 63.1
13
283
3D
2eqzA00 - 98.9
14
280
3D
1wz6A01 - 75.6
15
270
3D
2gzkA02 - 98.0
16
232
3D
1lwmA00 - 98.1
17
225
3D
2yqiA00 - 97.0
18
203
3D
1j3dA00 - 93.0
19
175
3D
1k99A00 - 28.0
20
160
3D
2e6oA00 - 23.4
21
151
3D
1v64A00 - 34.6
22
145
3D
1v63A00 - 68.5
23
141
3D
2hdzA00 - 29.4
24
127 - - 86.6
25
125 - - 15.7
26
121
3D
2cs1A00 - 98.3
28
118
3D
2d7lA01 - 100.0
27
117 - - 83.9
29
106 - - 27.1
30
103 - - 49.2
31
102 - - 22.0
32
99 - - 46.5
33
91 - - 40.7
34
88 - - 28.5
35
74
3D
2ctoA01 - 76.6
36
73
3D
1wxlA00 - 85.2
37
61 - - 80.0
43
57
3D
4nodH02 - 89.5
38
54 - - 86.1
39
53 - - 48.3
40
sex determining region Y
52 - - 35.4
41
48 - - 92.7
45
47
3D
4nodH01 - 62.9
42
47 - - 88.0
44
46 - - 71.9
46
38 - - 90.2
47
34 - - 64.2
48
27 - - 71.1
49
24 - - 76.4
50
23 - - 71.8
52
21 - - 72.4
51
21 - - 42.6
55
19 - - 77.1
56
19 - - 93.7
54
19 - - 83.9
53
19 - - 39.2
57
17 - - 85.3
58
16 - - 20.3
60
15 - - 91.6
62
15 - - 89.2
61
15 - - 15.7
64
15
3D
4s2qD00 - 36.4
59
15 - - 76.0
63
14 - - 12.3
65
13 - - 47.2
67
13 - - 87.5
66
13 - - 4.0
68
13 - - 23.0
71
12 - - 78.5
69
12 - - 10.0
70
12 - - 16.1
73
11 - - 90.6
72
11 - - 69.4
78
10 - - 0.0
81
10 - - 12.7
76
10 - - 71.8
79
10 - - 16.7
80
10 - - 0.0
74
10 - - 32.4
77
10 - - 20.5
75
10 - - 41.2
82
9 - - 15.2
83
9 - - 44.4
84
8 - - 30.4
86
8 - - 76.9
85
8 - - 16.4
87
7 - - 9.7
90
6 - - 10.9
89
6 - - 50.6
93
6 - - 93.6
92
6 - - 63.5
91
High mobility group
6 - - 4.1
88
6 - - 18.0
144
6
3D
1nhnA00 - 41.1
95
5 - - 8.8
96
5 - - 11.5
97
5 - - 8.3
94
5 - - 37.6
102
4 - - 10.1
109
4 - - 4.7
106
4 - - 50.6
101
4 - - 20.2
110
4 - - 50.4
104
4 - - 21.5
98
4 - - 45.5
99
4 - - 13.0
108
4 - - 5.1
103
4 - - 12.4
107
4 - - 4.9
100
4 - - 58.1
105
HMG
4 - - 7.0
118
3 - - 0.0
114
3 - - 0.0
112
3 - - 10.0
121
3 - - 6.7
117
3 - - 6.0
119
3 - - 0.0
115
3 - - 1.7
113
3 - - 12.8
123
3 - - 40.2
116
3 - - 2.8
120
3 - - 1.3
122
3 - - 9.5
111
3 - - 61.9
127
2 - - 0.0
125
2 - - 0.0
138
2 - - 3.1
137
2 - - 0.0
139
2 - - 2.1
129
2 - - 0.0
135
2 - - 42.4
140
2 - - 0.0
124
2 - - 31.0
131
AFU_orthologue AFUA_1G10040
2 - - 0.0
126
2 - - 0.0
142
2 - - 1.4
133
2 - - 5.6
136
High mobility group
2 - - 23.5
141
2 - - 0.0
128
2 - - 49.6
134
2 - - 0.0
130
2 - - 12.5
143
2 - - 46.9
132
AFU_orthologue AFUA_1G10040
2 - - 0.0
200
1 - - 0.0
190
1 - - 0.0
161
1 - - 0.0
194
1 - - 0.0
163
1 - - 0.0
151
1 - - 0.0
175
1 - - 0.0
148
1 - - 0.0
157
1 - - 0.0
197
1 - - 0.0
199
1 - - 0.0
153
1 - - 0.0
165
1 - - 0.0
198
1 - - 0.0
186
1 - - 0.0
147
1 - - 0.0
168
1 - - 0.0
202
1 - - 0.0
184
1 - - 0.0
191
HMG
1 - - 0.0
172
1 - - 0.0
145
1 - - 0.0
178
1 - - 0.0
187
HMG
1 - - 0.0
181
1 - - 0.0
154
1 - - 0.0
159
1 - - 0.0
160
1 - - 0.0
176
1 - - 0.0
195
1 - - 0.0
170
1 - - 0.0
193
1 - - 0.0
180
1 - - 0.0
179
1 - - 0.0
162
1 - - 0.0
182
1 - - 0.0
201
1 - - 0.0
152
1 - - 0.0
189
1 - - 0.0
167
1 - - 0.0
174
1 - - 0.0
149
1 - - 0.0
173
1 - - 0.0
188
1 - - 0.0
166
1 - - 0.0
156
1 - - 0.0
192
1 - - 0.0
177
1 - - 0.0
150
1 - - 0.0
155
1 - - 0.0
158
1 - - 0.0
185
1 - - 0.0
183
1 - - 0.0
146
1 - - 0.0
169
1 - - 0.0
164
1 - - 0.0
196
1 - - 0.0
171
1 - - 0.0