The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 4: Transcription and mRNA export factor SUS1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
3 Q6WNK7 (/IPI) Q6WNK7 (/IPI) Q6WNK7 (/IPI)
Enzyme activator activity GO:0008047
Binds to and increases the activity of an enzyme.
3 Q6WNK7 (/IDA) Q6WNK7 (/IDA) Q6WNK7 (/IDA)

There are 9 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery GO:0000973
The chromosome organization process in which the DNA sequence containing a gene transcribed by RNA polymerase II is maintained in a specific location at the nuclear periphery even after transcription has been repressed.
3 Q6WNK7 (/IMP) Q6WNK7 (/IMP) Q6WNK7 (/IMP)
Transcription elongation from RNA polymerase II promoter GO:0006368
The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase II promoter by the addition of ribonucleotides catalyzed by RNA polymerase II.
3 Q6WNK7 (/IMP) Q6WNK7 (/IMP) Q6WNK7 (/IMP)
Histone deubiquitination GO:0016578
The modification of histones by removal of ubiquitin groups.
3 Q6WNK7 (/IMP) Q6WNK7 (/IMP) Q6WNK7 (/IMP)
Poly(A)+ mRNA export from nucleus GO:0016973
The directed movement of poly(A)+ mRNA out of the nucleus into the cytoplasm.
3 Q6WNK7 (/IMP) Q6WNK7 (/IMP) Q6WNK7 (/IMP)
Regulation of protein localization GO:0032880
Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location.
3 Q6WNK7 (/IMP) Q6WNK7 (/IMP) Q6WNK7 (/IMP)
Histone H3-K79 methylation GO:0034729
The modification of histone H3 by addition of a methyl group to lysine at position 79 of the histone.
3 Q6WNK7 (/IMP) Q6WNK7 (/IMP) Q6WNK7 (/IMP)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
3 Q6WNK7 (/IMP) Q6WNK7 (/IMP) Q6WNK7 (/IMP)
Histone H3-K4 methylation GO:0051568
The modification of histone H3 by addition of one or more methyl groups to lysine at position 4 of the histone.
3 Q6WNK7 (/IMP) Q6WNK7 (/IMP) Q6WNK7 (/IMP)
Nuclear retention of pre-mRNA at the site of transcription GO:0071033
The process involved in retention of aberrant or improperly formed mRNAs, e.g. those that are incorrectly or incompletely spliced or that have incorrectly formed 3'-ends, within the nucleus at the site of transcription.
3 Q6WNK7 (/IMP) Q6WNK7 (/IMP) Q6WNK7 (/IMP)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
SAGA complex GO:0000124
A SAGA-type histone acetyltransferase complex that contains Spt8 (in budding yeast) or a homolog thereof; additional polypeptides include Spt group, consisting of Spt7, Spt3, and Spt20/Ada5, which interact with the TATA-binding protein (TBP); the Ada group, consisting of Ada1, Ada2, Ada3, Ada4/Gcn5, and Ada5/Spt20, which is functionally linked to the nucleosomal HAT activity; Tra1, an ATM/PI-3 kinase-related protein that targets DNA-bound activators for recruitment to promoters; the TBP-associated factor (TAF) proteins, consisting of Taf5, Taf6, Taf9, Taf10, and Taf12, which mediate nucleosomal HAT activity and are thought to help recruit the basal transcription machinery; the ubiquitin specifc protease Ubp-8.
3 Q6WNK7 (/IDA) Q6WNK7 (/IDA) Q6WNK7 (/IDA)
Nuclear pore GO:0005643
Any of the numerous similar discrete openings in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined.
3 Q6WNK7 (/IDA) Q6WNK7 (/IDA) Q6WNK7 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
3 Q6WNK7 (/IDA) Q6WNK7 (/IDA) Q6WNK7 (/IDA)
Transcription export complex 2 GO:0070390
A protein complex that couples SAGA-dependent gene expression to mRNA export at the inner side of the nuclear pore complex (NPC). The TREX-2 complex is tethered to the inner side of the NPC via the nucleoporins Nup1 and Nup60; in S. cerevisiae it contains Sac3p, Thp1p, Sem1, Sus1p and Cdc31p.
3 Q6WNK7 (/IDA) Q6WNK7 (/IDA) Q6WNK7 (/IDA)
DUBm complex GO:0071819
A protein complex that forms part of SAGA-type complexes SAGA and SLIK, and mediates deubiquitination of histone H2B. In S. cerevisiae, the DUBm consists of the proteins Ubp8p, Sgf11p, Sus1p, and Sgf73p.
3 Q6WNK7 (/IDA) Q6WNK7 (/IDA) Q6WNK7 (/IDA)