The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
3'5'-cyclic nucleotide phosphodiesterase, catalytic domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 21: Phosphodiesterase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
3',5'-cyclic-nucleotide phosphodiesterase activity GO:0004114
Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate.
3 Q388U6 (/ISM) Q388U6 (/ISM) Q8WSK2 (/ISM)

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Negative regulation of reactive oxygen species metabolic process GO:2000378
Any process that stops, prevents or reduces the frequency, rate or extent of reactive oxygen species metabolic process.
4 Q388U6 (/ISO) Q388U6 (/ISO) Q6S998 (/ISO) Q8WSK2 (/ISO)
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
3 Q388U6 (/ISM) Q388U6 (/ISM) Q8WSK2 (/ISM)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
5 Q388U6 (/IDA) Q388U6 (/IDA) Q57V52 (/IDA) Q57V52 (/IDA) Q8WSK2 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 E9AEA6 (/ISO) Q6S998 (/ISO)
Ciliary pocket GO:0020016
Invagination of the plasma membrane from which a cilium (also called flagellum) protrudes.
2 Q57V52 (/IDA) Q57V52 (/IDA)
Ciliary pocket GO:0020016
Invagination of the plasma membrane from which a cilium (also called flagellum) protrudes.
1 E9AEA6 (/ISO)