1 keywords

CATH Domain 6i6xB02

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.20 Alpha-Beta Barrel
Topology 3.20.20 TIM Barrel
Homologous Superfamily 3.20.20.80 Glycosidases

Domain Context

CATH Clusters

Superfamily Glycosidases
Functional Family Alpha-L-iduronidase

Enzyme Information

3.2.1.76
L-iduronidase.
based on mapping to UniProt P35475
Hydrolysis of unsulfated alpha-L-iduronosidic linkages in dermatan sulfate.

UniProtKB Entries (1)

P35475
IDUA_HUMAN
Homo sapiens
Alpha-L-iduronidase

PDB Structure

PDB 6I6X
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
New Irreversible alpha-l-Iduronidase Inhibitors and Activity-Based Probes.
Artola, M., Kuo, C.L., McMahon, S.A., Oehler, V., Hansen, T., van der Lienden, M., He, X., van den Elst, H., Florea, B.I., Kermode, A.R., van der Marel, G.A., Gloster, T.M., Codee, J.D.C., Overkleeft, H.S., Aerts, J.M.F.G.
Chemistry