Topology: 3.20.20

Molscript image for 7odcA02
Representative domain: 7odcA02
PDB coordinates for domain 7odcA02

TIM Barrel

Classification Lineage (3.20.20)

CATH CodeLevel DescriptionLinks
3 Alpha Beta
3.20 Alpha-Beta Barrel
3.20.20 TIM Barrel

Summary of Non-Redundant Representatives

- - - 28 384 602 763 2070 6106

Homologous Superfamily Entries in Topology 3.20.20 (28)

CATH Level CATH codeName Representative Domain Representative Keywords Representative Thumbnail Number of Domains
3.20.20.10Alanine racemase 7odcA02 Mus musculusOrnithine decarboxylasePositive regulation of cell proliferationKidney developmentOrnithine decarboxylase. Molscript image for 7odcA02 141
3.20.20.20Dihydropteroate (DHP) synthetase 3bofA02 Thermotoga maritimaOne carbon pool by folate5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]5-methyltetrahydrofolate S-homocysteine methyltransferaseCysteine and methionine metabolism Molscript image for 3bofA02 55
3.20.20.30FMN dependent fluorescent proteins 1lucB00 Alkanal monooxygenase beta chainAlkanal monooxygenase (FMN-linked).Vibrio harveyi Molscript image for 1lucB00 43
3.20.20.407-stranded glycosidases (cellulases) 1oc7A00 Humicola insolensCellulose 1,4-beta-cellobiosidase.Exoglucanase-6A Molscript image for 1oc7A00 38
3.20.20.60Phosphoenolpyruvate-binding domains 1xg4D00 Methylisocitrate lyase [EC:4.1.3.30]Methylisocitrate lyaseMethylisocitrate lyase.Propanoate metabolismEscherichia coli K-12 Molscript image for 1xg4D00 247
3.20.20.70Aldolase class I 2vxnA00 Triosephosphate isomeraseTriose-phosphate isomerase.Leishmania mexicana Molscript image for 2vxnA00 2158
3.20.20.80Glycosidases 1itxA01 Bacillus circulansChitinase.Chitinase A1 Molscript image for 1itxA01 1462
3.20.20.100NADP-dependent oxidoreductase 1us0A00 Galactose metabolismAldehyde reductase.Aldose reductasePyruvate metabolismFructose and mannose metabolism Molscript image for 1us0A00 282
3.20.20.105tRNA-guanine (tRNA-G) transglycosylase 1r5yA00 Queuine tRNA-ribosyltransferaseTRNA-guanine transglycosylase.Zymomonas mobilisQueuine tRNA-ribosyltransferase [EC:2.4.2.29] Molscript image for 1r5yA00 75
3.20.20.110Rubisco 1wddA02 Ribulose-bisphosphate carboxylase large chain [EC:4.1.1.39]Carbon fixation in photosynthetic organismsRibulose bisphosphate carboxylase large chainOryza sativa Japonica GroupRibulose-bisphosphate carboxylase. Molscript image for 1wddA02 262
3.20.20.120Enolase superfamily 1kkoA02 3-methylaspartate ammonia-lyaseCitrobacter amalonaticus Molscript image for 1kkoA02 439
3.20.20.140Metal-dependent hydrolases 2ob3A00 Parathion hydrolaseBrevundimonas diminutaAryldialkylphosphatase. Molscript image for 2ob3A00 368
3.20.20.150Divalent-metal-dependent TIM barrel enzymes 1muwA00 Xylose isomerase.Xylose isomeraseStreptomyces olivochromogenes Molscript image for 1muwA00 201
3.20.20.190Phosphatidylinositol (PI) phosphodiesterase 3ch0A00 Cytophaga hutchinsonii ATCC 33406Glycerophosphodiester phosphodiesterase.Glycerophospholipid metabolismGlycerophosphoryl diester phosphodiesterase [EC:3.1.4.46]Glycerophosphodiester phosphodiesterase Molscript image for 3ch0A00 80
3.20.20.210 1r3sA00 Porphyrin and chlorophyll metabolismUroporphyrinogen decarboxylase.Uroporphyrinogen decarboxylase [EC:4.1.1.37]Uroporphyrinogen decarboxylase activityHomo sapiens Molscript image for 1r3sA00 62
3.20.20.220 3fstA00 One carbon pool by folateMethylenetetrahydrofolate reductase (NAD(P)H).5,10-methylenetetrahydrofolate reductaseMethylenetetrahydrofolate reductase (NADPH) [EC:1.5.1.20]Methane metabolism Molscript image for 3fstA00 33
3.20.20.240 1ccwB01 Methylaspartate mutase.Methylaspartate mutase E chainClostridium cochlearium Molscript image for 1ccwB01 38
3.20.20.300 1x38A01 Beta-D-glucan exohydrolase isoenzyme ExoIHordeum vulgare subsp. vulgare Molscript image for 1x38A01 15
3.20.20.330 1q7zA01 Thermotoga maritimaOne carbon pool by folate5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]5-methyltetrahydrofolate S-homocysteine methyltransferaseCysteine and methionine metabolism Molscript image for 1q7zA01 24
3.20.20.350 1eexA00 Klebsiella oxytocaPropanediol dehydratase.Diol dehydrase alpha subunit Molscript image for 1eexA00 18
3.20.20.360Malate synthase, domain 3 1p7tA03 Pyruvate metabolismMalate synthase [EC:2.3.3.9]Glyoxylate and dicarboxylate metabolismEscherichia coli K-12Metabolic pathways Molscript image for 1p7tA03 9
3.20.20.370Glycoside hydrolase/deacetylase 2i5iA00 Hypothetical proteinEnterococcus faecalisUPF0249 protein EF_3048 Molscript image for 2i5iA00 27
3.20.20.380CutC-like (Pfam 03932) 1twdB00 Shigella flexneriCopper homeostasis proteinCopper homeostasis protein cutC Molscript image for 1twdB00 6
3.20.20.390FMN-linked oxidoreductases 2f6uA00 Phosphoglycerol geranylgeranyltransferase.Geranylgeranylglyceryl phosphate synthaseArchaeoglobus fulgidus Molscript image for 2f6uA00 6
3.20.20.400GlpP-like 1vkfA00 Thermotoga maritimaGlycerol uptake operon antiterminatorGlycerol uptake operon antiterminator-related protein Molscript image for 1vkfA00 4
3.20.20.410Hypothetical protein tm1631. 1vpqA00 Thermotoga maritimaPutative uncharacterized protein Molscript image for 1vpqA00 4
3.20.20.440D-lysine 5,6-aminomutase alpha subunit. Chain A 1xrsA00 D-lysine 5,6-aminomutase alpha subunitClostridium sticklandiiProtein binding Molscript image for 1xrsA00 1
3.20.20.450EAL domain-like 2r6oB00 Thiobacillus denitrificans ATCC 25259Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) Molscript image for 2r6oB00 8

Close Structural Clusters 3.20.20 (< 5Å)

Summary of "distant" structural clusters found within this level of CATH.
Cluster ID Example Domain Domains in Cluster Structural Alignment (Core) Structural Alignment (Expanded)
00003.00020.00020.00010/SSG5/1 1ct5A00 11
00003.00020.00020.00100/SSG5/1 3eauA00 5
00003.00020.00020.00100/SSG5/2 1mi3A00 5
00003.00020.00020.00105/SSG5/1 1r5yA00 2
00003.00020.00020.00110/SSG5/1 2d69A02 4
00003.00020.00020.00120/SSG5/1 2qjjC02 10
00003.00020.00020.00120/SSG5/2 3dgbA02 14
00003.00020.00020.00120/SSG5/3 1tzzA02 13
00003.00020.00020.00140/SSG5/1 1bf6A00 2
00003.00020.00020.00140/SSG5/2 2imrA02 2
00003.00020.00020.00140/SSG5/3 2vhlA02 2
00003.00020.00020.00140/SSG5/4 2ffiA00 3
00003.00020.00020.00140/SSG5/5 3feqC02 2
00003.00020.00020.00140/SSG5/6 1gkpB02 2
00003.00020.00020.00140/SSG5/7 3e74B02 4
00003.00020.00020.00140/SSG5/8 1ituA00 5
00003.00020.00020.00140/SSG5/9 2q01A01 2
00003.00020.00020.00140/SSG5/10 3cjpA00 6
00003.00020.00020.00140/SSG5/11 1m65A00 2
00003.00020.00020.00140/SSG5/12 1ra0A02 7
00003.00020.00020.00150/SSG5/1 1muwA00 2
00003.00020.00020.00150/SSG5/2 3dx5A00 5
00003.00020.00020.00150/SSG5/3 1qtwA00 2
00003.00020.00020.00150/SSG5/4 1yx1A00 2
00003.00020.00020.00190/SSG5/1 1o1zA00 6
00003.00020.00020.00190/SSG5/2 2plcA00 2
00003.00020.00020.00020/SSG5/1 2bmbA02 5
00003.00020.00020.00210/SSG5/1 1r3sA00 3
00003.00020.00020.00210/SSG5/2 1ypxA00 2
00003.00020.00020.00030/SSG5/1 1ezwA00 2
00003.00020.00020.00030/SSG5/2 3c8nD00 6
00003.00020.00020.00300/SSG5/1 2oxnA00 2
00003.00020.00020.00370/SSG5/1 2nlyA00 3
00003.00020.00020.00040/SSG5/1 3a9bA00 3
00003.00020.00020.00410/SSG5/1 1vpyA00 2
00003.00020.00020.00450/SSG5/1 2basB01 2
00003.00020.00020.00060/SSG5/1 1izcA00 2
00003.00020.00020.00060/SSG5/2 1s2wA00 3
00003.00020.00020.00060/SSG5/3 2bg5A00 3
00003.00020.00020.00060/SSG5/4 2qiwA01 2
00003.00020.00020.00060/SSG5/5 1u5hA00 3
00003.00020.00020.00070/SSG5/1 1tqjC00 10
00003.00020.00020.00070/SSG5/2 1wbhB00 5
00003.00020.00020.00070/SSG5/3 1zfjA00 2
00003.00020.00020.00070/SSG5/4 2qf7A04 3
00003.00020.00020.00070/SSG5/5 1vyrA00 4
00003.00020.00020.00070/SSG5/6 1p4cA00 3
00003.00020.00020.00070/SSG5/7 1qopA00 3
00003.00020.00020.00070/SSG5/8 1b3oA00 4
00003.00020.00020.00070/SSG5/9 3lb0A00 3
00003.00020.00020.00070/SSG5/10 1to3A00 2
00003.00020.00020.00070/SSG5/11 1uasA01 2
00003.00020.00020.00070/SSG5/12 2zdrA01 3
00003.00020.00020.00070/SSG5/13 3gvgA00 3
00003.00020.00020.00070/SSG5/14 2wkjA00 10
00003.00020.00020.00070/SSG5/15 1x1oA02 3
00003.00020.00020.00070/SSG5/16 1d3gA00 4
00003.00020.00020.00070/SSG5/17 2p0oA01 2
00003.00020.00020.00070/SSG5/18 1xi3A00 3
00003.00020.00020.00070/SSG5/19 1yxyA00 2
00003.00020.00020.00070/SSG5/20 2iqtA00 2
00003.00020.00020.00070/SSG5/21 3c6cA00 2
00003.00020.00020.00070/SSG5/22 3f4wA00 5
00003.00020.00020.00070/SSG5/23 3elfA00 2
00003.00020.00020.00070/SSG5/24 2qr6A02 2
00003.00020.00020.00070/SSG5/25 1thfD00 3
00003.00020.00020.00070/SSG5/26 1ub3A00 6
00003.00020.00020.00080/SSG5/1 3edfA02 5
00003.00020.00020.00080/SSG5/2 1mxgA01 2
00003.00020.00020.00080/SSG5/3 1ua7A01 2
00003.00020.00020.00080/SSG5/4 1w32A00 5
00003.00020.00020.00080/SSG5/5 1sfsA00 3
00003.00020.00020.00080/SSG5/6 3cmgA03 7
00003.00020.00020.00080/SSG5/7 1nowA02 3
00003.00020.00020.00080/SSG5/8 1nofA02 3
00003.00020.00020.00080/SSG5/9 1ug6A00 6
00003.00020.00020.00080/SSG5/10 1qnrA00 3
00003.00020.00020.00080/SSG5/11 1wdpA00 2
00003.00020.00020.00080/SSG5/12 1ceoA00 4
00003.00020.00020.00080/SSG5/13 3fndA01 6
00003.00020.00020.00080/SSG5/14 1w9pA01 5
00003.00020.00020.00080/SSG5/15 2ebnA00 2
00003.00020.00020.00080/SSG5/16 1ji1A02 3
00003.00020.00020.00080/SSG5/17 1fobA00 2
00003.00020.00020.00080/SSG5/18 1iv8A01 4


Distant Structural Clusters 3.20.20 (< 9Å)

Summary of "distant" structural clusters found within this level of CATH.
Cluster ID Example Domain Domains in Cluster Structural Alignment (Core) Structural Alignment (Expanded)
00003.00020.00020.00100/SSGA9/1 1pyfA00 2
00003.00020.00020.00120/SSGA9/1 2oqhA02 4
00003.00020.00020.00140/SSGA9/1 1rk6A02 11
00003.00020.00020.00140/SSGA9/2 1ejxC02 2
00003.00020.00020.00140/SSGA9/3 1j5sA01 2
00003.00020.00020.00150/SSGA9/1 1qtwA00 5
00003.00020.00020.00150/SSGA9/2 1yx1A00 2
00003.00020.00020.00190/SSGA9/1 1djxA02 3
00003.00020.00020.00210/SSGA9/1 1ypxA00 3
00003.00020.00020.00030/SSGA9/1 2i7gA00 3
00003.00020.00020.00370/SSGA9/1 2nlyA00 3
00003.00020.00020.00060/SSGA9/1 1s2wA00 3
00003.00020.00020.00060/SSGA9/2 2olsA04 2
00003.00020.00020.00070/SSGA9/1 1ps9A01 2
00003.00020.00020.00070/SSGA9/2 1r30A00 2
00003.00020.00020.00070/SSGA9/3 3cc1B01 2
00003.00020.00020.00070/SSGA9/4 1w5qB00 2
00003.00020.00020.00070/SSGA9/5 1gvfB00 6
00003.00020.00020.00070/SSGA9/6 1me8A00 3
00003.00020.00020.00070/SSGA9/7 3f4wA00 12
00003.00020.00020.00070/SSGA9/8 1nvmA01 2
00003.00020.00020.00070/SSGA9/9 1of8A00 3
00003.00020.00020.00070/SSGA9/10 1ofdA02 2
00003.00020.00020.00070/SSGA9/11 2e6fA01 5
00003.00020.00020.00080/SSGA9/1 1j0hA02 4
00003.00020.00020.00080/SSGA9/2 1h1nA00 9
00003.00020.00020.00080/SSGA9/3 1zjaA01 3
00003.00020.00020.00080/SSGA9/4 1vemA01 3
00003.00020.00020.00080/SSGA9/5 1ht6A01 2
00003.00020.00020.00080/SSGA9/6 1l8nA02 4
00003.00020.00020.00080/SSGA9/7 2vx5A00 5