CATH Classification

Domain Context

CATH Clusters

Superfamily Homocysteine-binding-like domain
Functional Family Betaine--homocysteine S-methyltransferase 1

Enzyme Information

2.1.1.5
Betaine--homocysteine S-methyltransferase.
based on mapping to UniProt Q93088
Trimethylammonioacetate + L-homocysteine = dimethylglycine + L-methionine.

UniProtKB Entries (1)

Q93088
BHMT1_HUMAN
Homo sapiens
Betaine--homocysteine S-methyltransferase 1

PDB Structure

PDB 4M3P
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Specific potassium ion interactions facilitate homocysteine binding to betaine-homocysteine S-methyltransferase.
Mladkova, J., Hladilkova, J., Diamond, C.E., Tryon, K., Yamada, K., Garrow, T.A., Jungwirth, P., Koutmos, M., Jiracek, J.
Proteins