CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.20 | Alpha-Beta Barrel | |
3.20.20 | TIM Barrel | |
3.20.20.80 | Glycosidases |
Domain Context
CATH Clusters
Superfamily | Glycosidases |
Functional Family |
Enzyme Information
2.4.1.248 |
Cycloisomaltooligosaccharide glucanotransferase.
based on mapping to UniProt P94286
Cyclizes part of a (1->6)-alpha-D-glucan chain by formation of a (1->6)- alpha-D-glucosidic bond.
-!- Specific for (1->6)-alpha-D-glucans (dextrans) and, unlike cyclomaltodextrin glucanotransferase (EC 2.4.1.19), without activity toward (1->4)-alpha-D-glucans, such as amylose. -!- It also has no activity on oligosaccharides, such as amylopectin and pullulan, containing (1->6)-alpha-D-glucosidic linkages at branch points. -!- The enzyme from Bacillus circulans T-3040 has been shown to form cycloisomalto-oligosaccharides of three sizes (7, 8 and 9 glucose units). -!- It will also catalyze the disproportionation of two isomalto- oligosaccharides molecules to yield a series of isomalto- oligosachharides and the addition of D-glucose to cycloisomalto- oligosaccharides with ring opening to form isomalto-oligosaccharides.
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UniProtKB Entries (1)
P94286 |
CTA1_BACCI
Bacillus circulans
Cycloisomaltooligosaccharide glucanotransferase
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PDB Structure
PDB | 3WNO |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Structural elucidation of the cyclization mechanism of alpha-1,6-glucan by Bacillus circulans T-3040 cycloisomaltooligosaccharide glucanotransferase.
J.Biol.Chem.
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