1 keywords

CATH Domain 3vavA00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.20 Alpha-Beta Barrel
Topology 3.20.20 TIM Barrel
Homologous Superfamily 3.20.20.60 Phosphoenolpyruvate-binding domains

Domain Context

CATH Clusters

Superfamily Phosphoenolpyruvate-binding domains
Functional Family 3-methyl-2-oxobutanoate hydroxymethyltransferase

Enzyme Information

2.1.2.11
3-methyl-2-oxobutanoate hydroxymethyltransferase.
based on mapping to UniProt Q2SYZ1
5,10-methylenetetrahydrofolate + 3-methyl-2-oxobutanoate + H(2)O = tetrahydrofolate + 2-dehydropantoate.

UniProtKB Entries (1)

Q2SYZ1
PANB_BURTA
Burkholderia thailandensis E264
3-methyl-2-oxobutanoate hydroxymethyltransferase

PDB Structure

PDB 3VAV
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Combining functional and structural genomics to sample the essential Burkholderia structome.
Baugh, L., Gallagher, L.A., Patrapuvich, R., Clifton, M.C., Gardberg, A.S., Edwards, T.E., Armour, B., Begley, D.W., Dieterich, S.H., Dranow, D.M., Abendroth, J., Fairman, J.W., Fox, D., Staker, B.L., Phan, I., Gillespie, A., Choi, R., Nakazawa-Hewitt, S., Nguyen, M.T., Napuli, A., Barrett, L., Buchko, G.W., Stacy, R., Myler, P.J., Stewart, L.J., Manoil, C., Van Voorhis, W.C.
Plos One