CATH Classification

Domain Context

CATH Clusters

Superfamily Metal-dependent hydrolases
Functional Family Phospho-furanose lactonase

Enzyme Information

3.1.1.25
1,4-lactonase.
based on mapping to UniProt Q4A724
A 1,4-lactone + H(2)O = a 4-hydroxyacid.
-!- Specific for 1,4-lactones with 4-8 carbon atoms. -!- Does not hydrolyze simple aliphatic esters, acetylcholine, sugar lactones or substituted aliphatic lactones, e.g. 3-hydroxy-4- butyrolactone.

UniProtKB Entries (1)

Q4A724
PFLAC_MYCS5
Mycoplasma synoviae 53
Phospho-furanose lactonase

PDB Structure

PDB 3OVG
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The crystal structure of an amidohydrolase from Mycoplasma synoviae with Zn ion bound
Zhang, Z., Kumaran, D., Burley, S.K., Swaminathan, S.
To be Published