CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family

Enzyme Information

3.6.4.13
RNA helicase.
based on mapping to UniProt P53131
ATP + H(2)O = ADP + phosphate.
-!- RNA helicases utilize the energy from ATP hydrolysis to unwind RNA. -!- Some of them unwind RNA with a 3' to 5' polarity, other show 5' to 3' polarity. -!- Some helicases unwind DNA as well as RNA. -!- May be identical with EC 3.6.4.12 (DNA helicase).

UniProtKB Entries (1)

P53131
PRP43_YEAST
Saccharomyces cerevisiae S288C
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

PDB Structure

PDB 3KX2
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural basis for the function of DEAH helicases
He, Y., Andersen, G.R., Nielsen, K.H.
Embo Rep.