CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.20 | Alpha-Beta Barrel | |
3.20.20 | TIM Barrel | |
3.20.20.70 | Aldolase class I |
Domain Context
CATH Clusters
Superfamily | Aldolase class I |
Functional Family | 3-hydroxy-5-phosphonooxypentane-2,4-dione thiolase |
Enzyme Information
2.3.1.245 |
3-hydroxy-5-phosphonooxypentane-2,4-dione thiolase.
based on mapping to UniProt P76143
Glycerone phosphate + acetyl-CoA = 3-hydroxy-5-phosphonooxypentane-2,4- dione + coenzyme A.
-!- The enzyme participates in a degradation pathway of the bacterial quorum-sensing autoinducer molecule AI-2.
|
UniProtKB Entries (1)
P76143 |
LSRF_ECOLI
Escherichia coli K-12
3-hydroxy-5-phosphonooxypentane-2,4-dione thiolase
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PDB Structure
PDB | 3GKF |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
The crystal structure of the Escherichia coli autoinducer-2 processing protein LsrF.
Plos One
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