CATH Classification

Domain Context

CATH Clusters

Superfamily Aldolase class I
Functional Family tRNA-dihydrouridine(20/20a) synthase

Enzyme Information

1.3.1.91
tRNA-dihydrouridine(20) synthase (NAD(P)(+)).
based on mapping to UniProt Q5SMC7
5,6-dihydrouracil(20) in tRNA + NAD(P)(+) = uracil(20) in tRNA + NAD(P)H.
-!- The enzyme specifically modifies uracil(20) in tRNA.
1.3.1.-
With NAD(+) or NADP(+) as acceptor.
based on mapping to UniProt Q5SMC7

UniProtKB Entries (1)

Q5SMC7
DUSAL_THET8
Thermus thermophilus HB8
TRNA-dihydrouridine(20/20a) synthase

PDB Structure

PDB 3B0U
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Molecular basis of dihydrouridine formation on tRNA
Yu, F., Tanaka, Y., Yamashita, K., Suzuki, T., Nakamura, A., Hirano, N., Suzuki, T., Yao, M., Tanaka, I.
Proc.Natl.Acad.Sci.USA