CATH Classification

Domain Context

CATH Clusters

Superfamily Dihydrodipicolinate Reductase; domain 2
Functional Family

Enzyme Information

1.2.1.59
Glyceraldehyde-3-phosphate dehydrogenase (NAD(P)(+)) (phosphorylating).
based on mapping to UniProt Q58546
D-glyceraldehyde 3-phosphate + phosphate + NAD(P)(+) = 3-phospho-D- glyceroyl phosphate + NAD(P)H.
-!- NAD(+) and NADP(+) can be used as cofactors with similar efficiency, unlike EC 1.2.1.12 and EC 1.2.1.13, which are NAD(+)- and NADP(+)- dependent, respectively.

UniProtKB Entries (1)

Q58546
G3P_METJA
Methanocaldococcus jannaschii DSM 2661
Glyceraldehyde-3-phosphate dehydrogenase

PDB Structure

PDB 2YYY
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure of glyceraldehyde-3-phosphate dehydrogenase from the archaeal hyperthermophile Methanocaldococcus jannaschii.
Malay, A.D., Bessho, Y., Ellis, M.J., Antonyuk, S.V., Strange, R.W., Hasnain, S.S., Shinkai, A., Padmanabhan, B., Yokoyama, S.
Acta Crystallogr.,Sect.F