CATH Classification

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family ephrin type-B receptor 4

Enzyme Information

2.7.10.1
Receptor protein-tyrosine kinase.
based on mapping to UniProt P54760
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
-!- The receptor protein-tyrosine kinases, which can be defined as having a transmembrane domain, are a large and diverse multigene family found only in metazoans. -!- In the human genome, 58 receptor-type protein-tyrosine kinases have been identified and these are distributed into 20 subfamilies. -!- Formerly EC 2.7.1.112.

UniProtKB Entries (1)

P54760
EPHB4_HUMAN
Homo sapiens
Ephrin type-B receptor 4

PDB Structure

PDB 2E7H
External Links
Method SOLUTION NMR
Organism
Primary Citation
Solution structure of the second fn3 domain from human Ephrin type-B receptor 4
Qin, X.R., Hayashi, F., Yokoyama, S.
To be Published