1 keywords

CATH Domain 2d1xC00

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.30 Roll
Topology 2.30.30 SH3 type barrels.
Homologous Superfamily 2.30.30.40 SH3 Domains

Domain Context

CATH Clusters

Superfamily SH3 Domains
Functional Family Src substrate cortactin

Enzyme Information

UniProtKB Entries (1)

Q14247
SRC8_HUMAN
Homo sapiens
Src substrate cortactin

PDB Structure

PDB 2D1X
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Targeting AMAP1 and cortactin binding bearing an atypical src homology 3/proline interface for prevention of breast cancer invasion and metastasis.
Hashimoto, S., Hirose, M., Hashimoto, A., Morishige, M., Yamada, A., Hosaka, H., Akagi, K., Ogawa, E., Oneyama, C., Agatsuma, T., Okada, M., Kobayashi, H., Wada, H., Nakano, H., Ikegami, T., Nakagawa, A., Sabe, H.
Proc.Natl.Acad.Sci.Usa