1 keywords

CATH Domain 2d1xA00

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.30 Roll
Topology 2.30.30 SH3 type barrels.
Homologous Superfamily 2.30.30.40 SH3 Domains

Domain Context

CATH Clusters

Superfamily SH3 Domains
Functional Family Src substrate cortactin

Enzyme Information

UniProtKB Entries (1)

Q9ULH1
ASAP1_HUMAN
Homo sapiens
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1

PDB Structure

PDB 2D1X
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Targeting AMAP1 and cortactin binding bearing an atypical src homology 3/proline interface for prevention of breast cancer invasion and metastasis.
Hashimoto, S., Hirose, M., Hashimoto, A., Morishige, M., Yamada, A., Hosaka, H., Akagi, K., Ogawa, E., Oneyama, C., Agatsuma, T., Okada, M., Kobayashi, H., Wada, H., Nakano, H., Ikegami, T., Nakagawa, A., Sabe, H.
Proc.Natl.Acad.Sci.Usa