CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.60 | Sandwich |
|
2.60.40 | Immunoglobulin-like |
|
2.60.40.10 | Immunoglobulins |
Domain Context
CATH Clusters
| Superfamily | Immunoglobulins |
| Functional Family | Myosin light chain kinase, smooth muscle |
Enzyme Information
| 2.7.11.18 |
[Myosin light-chain] kinase.
based on mapping to UniProt Q15746
ATP + [myosin light-chain] = ADP + [myosin light-chain] phosphate.
-!- Requires calmodulin for activity. -!- The 20 kDa light chain from smooth muscle myosin is phosphorylated more rapidly than any other acceptor, but light chains from other myosins and myosin itself can act as acceptors, more slowly. -!- Formerly EC 2.7.1.117.
|
UniProtKB Entries (1)
| Q15746 |
MYLK_HUMAN
Homo sapiens
Myosin light chain kinase, smooth muscle
|
PDB Structure
| PDB | 2CQV |
| External Links | |
| Method | SOLUTION NMR |
| Organism | |
| Primary Citation |
Solution structure of the eighth Ig-like domain of human myosin light chain kinase
To be Published
|