CATH Classification

Domain Context

CATH Clusters

Superfamily Aldolase class I
Functional Family NADPH-dependent 2,4-dienoyl-CoA reductase

Enzyme Information

1.3.1.34
2,4-dienoyl-CoA reductase (NADPH).
based on mapping to UniProt P42593
Trans-2,3-didehydroacyl-CoA + NADP(+) = trans,trans-2,3,4,5- tetradehydroacyl-CoA + NADPH.
-!- Best substrates for reduction contain a 2,4-diene structure with chain length C(8) or C(10).

UniProtKB Entries (1)

P42593
FADH_ECOLI
Escherichia coli K-12
2,4-dienoyl-CoA reductase

PDB Structure

PDB 1PS9
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The crystal structure and reaction mechanism of Escherichia coli 2,4-dienoyl-CoA reductase
Hubbard, P.A., Liang, X., Schulz, H., Kim, J.J.
J.Biol.Chem.