CATH Classification

Domain Context

CATH Clusters

Superfamily SH3 Domains
Functional Family Tyrosine-protein kinase

Enzyme Information

2.7.10.2
Non-specific protein-tyrosine kinase.
based on mapping to UniProt P41241
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
-!- Unlike EC 2.7.10.1, this protein-tyrosine kinase does not have a transmembrane domain. -!- In the human genome, 32 non-specific protein-tyrosine kinases have been identified and these can be divided into 10 families. -!- Formerly EC 2.7.1.112.

UniProtKB Entries (1)

P29352
PTN22_MOUSE
Mus musculus
Tyrosine-protein phosphatase non-receptor type 22

PDB Structure

PDB 1JEG
External Links
Method SOLUTION NMR
Organism Escherichia
Primary Citation
A novel, specific interaction involving the Csk SH3 domain and its natural ligand.
Ghose, R., Shekhtman, A., Goger, M.J., Ji, H., Cowburn, D.
Nat.Struct.Biol.