CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.20 | Alpha-Beta Barrel |
|
3.20.20 | TIM Barrel |
|
3.20.20.70 | Aldolase class I |
Domain Context
CATH Clusters
| Superfamily | Aldolase class I |
| Functional Family | peroxisomal (S)-2-hydroxy-acid oxidase GLO1 |
Enzyme Information
| 1.1.3.15 |
(S)-2-hydroxy-acid oxidase.
based on mapping to UniProt P05414
(S)-2-hydroxy acid + O(2) = 2-oxo acid + H(2)O(2).
-!- Exists as two major isoenzymes; the A form preferentially oxidizes short-chain aliphatic hydroxy acids; the B form preferentially oxidizes long-chain and aromatic hydroxy acids. -!- The rat isoenzyme B also acts as EC 1.4.3.2. -!- Formerly EC 1.1.3.1.
|
UniProtKB Entries (1)
| P05414 |
GOX_SPIOL
Spinacia oleracea
Peroxisomal (S)-2-hydroxy-acid oxidase
|
PDB Structure
| PDB | 1GYL |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Involvement of Tyr24 and Trp108 in substrate binding and substrate specificity of glycolate oxidase.
Eur.J.Biochem.
|