The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Ribonucleoside hydrolase-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1987: Inosine-uridine preferring nucleoside hydrolase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 21 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Uridine nucleosidase activity GO:0045437
Catalysis of the reaction: H(2)O + uridine = ribofuranose + uracil.
7 P22564 (/IDA) P33022 (/IDA) P41409 (/IDA) P83851 (/IDA) Q04179 (/IDA) Q4QDN1 (/IDA) Q9SJM7 (/IDA)
Inosine nucleosidase activity GO:0047724
Catalysis of the reaction: inosine + H2O = D-ribose + hypoxanthine.
4 P22564 (/IDA) P83851 (/IDA) Q4QDN1 (/IDA) Q9SJM7 (/IDA)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
3 P33022 (/IDA) P41409 (/IDA) P83851 (/IDA)
Ribosylpyrimidine nucleosidase activity GO:0050263
Catalysis of the reaction: an N-D-ribosylpyrimidine + H2O = D-ribose + a pyrimidine.
3 P22564 (/IDA) Q04179 (/IDA) Q4QDN1 (/IDA)
Purine nucleosidase activity GO:0008477
Catalysis of the reaction: a N-D-ribosylpurine + H2O = a purine + D-ribose.
2 P83851 (/IDA) Q4QDN1 (/IDA)
Uridine nucleosidase activity GO:0045437
Catalysis of the reaction: H(2)O + uridine = ribofuranose + uracil.
2 Q10314 (/ISO) Q9P6J4 (/ISO)
Adenosine nucleosidase activity GO:0047622
Catalysis of the reaction: adenosine + H2O = D-ribose + adenine.
2 P22564 (/IDA) Q9SJM7 (/IDA)
Ribosylpyrimidine nucleosidase activity GO:0050263
Catalysis of the reaction: an N-D-ribosylpyrimidine + H2O = D-ribose + a pyrimidine.
2 Q10314 (/ISO) Q9P6J4 (/ISO)
Nicotinamide riboside hydrolase activity GO:0070635
Catalysis of the reaction: nicotinamide riboside + H2O = nicotinamide + D-ribose.
2 Q10314 (/ISO) Q9P6J4 (/ISO)
Nicotinic acid riboside hydrolase activity GO:0070636
Catalysis of the reaction: nicotinic acid riboside + H2O = nicotinic acid + D-ribose.
2 Q10314 (/ISO) Q9P6J4 (/ISO)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 P41409 (/IPI)
Purine nucleosidase activity GO:0008477
Catalysis of the reaction: a N-D-ribosylpurine + H2O = a purine + D-ribose.
1 Q9I6Y9 (/IMP)
Purine nucleosidase activity GO:0008477
Catalysis of the reaction: a N-D-ribosylpurine + H2O = a purine + D-ribose.
1 Q5LQL8 (/ISS)
Hydrolase activity, acting on glycosyl bonds GO:0016798
Catalysis of the hydrolysis of any glycosyl bond.
1 Q7KWM9 (/ISS)
UDP-glucosyltransferase activity GO:0035251
Catalysis of the transfer of a glucosyl group from UDP-glucose to an acceptor molecule.
1 Q8LAC4 (/IDA)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 P33022 (/IDA)
Pyrimidine-5'-nucleotide nucleosidase activity GO:0047405
Catalysis of the reaction: H2O + a pyrimidine 5'-nucleotide = ribose-5-phosphate + a pyrimidine.
1 P41409 (/IDA)
Inosine nucleosidase activity GO:0047724
Catalysis of the reaction: inosine + H2O = D-ribose + hypoxanthine.
1 Q8LAC4 (/IMP)
Nicotinamide riboside hydrolase activity GO:0070635
Catalysis of the reaction: nicotinamide riboside + H2O = nicotinamide + D-ribose.
1 Q04179 (/IDA)
Nicotinic acid riboside hydrolase activity GO:0070636
Catalysis of the reaction: nicotinic acid riboside + H2O = nicotinic acid + D-ribose.
1 Q04179 (/IDA)
Xanthosine nucleotidase activity GO:0072585
Catalysis of the reaction: xanthosine + H2O = D-ribose + xanthine.
1 Q9SJM7 (/IDA)

There are 21 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Uridine catabolic process GO:0006218
The chemical reactions and pathways resulting in the breakdown of uridine, uracil riboside, a ribonucleoside very widely distributed but occurring almost entirely as phosphoric esters in ribonucleotides and ribonucleic acids.
2 Q04179 (/IMP) Q9SJM7 (/IMP)
Pyrimidine-containing compound salvage GO:0008655
Any process that generates a pyrimidine-containing compound, any nucleobase, nucleoside, nucleotide or nucleic acid that contains a pyrimidine base, from derivatives of them without de novo synthesis.
2 Q10314 (/ISO) Q9P6J4 (/ISO)
Nicotinate nucleotide salvage GO:0019358
The generation of nicotinate nucleotide without de novo synthesis.
2 Q10314 (/ISO) Q9P6J4 (/ISO)
NAD biosynthesis via nicotinamide riboside salvage pathway GO:0034356
The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD) from the vitamin precursor nicotinamide riboside.
2 Q10314 (/ISO) Q9P6J4 (/ISO)
Pyrimidine ribonucleoside catabolic process GO:0046133
The chemical reactions and pathways resulting in the breakdown of any ribonucleoside, a nucleoside in which a pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule.
2 P33022 (/IMP) P41409 (/IMP)
Pyrimidine nucleoside catabolic process GO:0046135
The chemical reactions and pathways resulting in the breakdown of one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).
2 Q10314 (/ISO) Q9P6J4 (/ISO)
Inosine catabolic process GO:0006148
The chemical reactions and pathways resulting in the breakdown of inosine, hypoxanthine riboside, a nucleoside found free but not in combination in nucleic acids except in the anticodons of some tRNAs.
1 Q8LAC4 (/IMP)
Purine nucleoside catabolic process GO:0006152
The chemical reactions and pathways resulting in the breakdown of purine nucleoside, one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).
1 Q9SJM7 (/IMP)
Purine nucleotide metabolic process GO:0006163
The chemical reactions and pathways involving a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
1 Q9I6Y9 (/IMP)
Cytidine catabolic process GO:0006216
The chemical reactions and pathways resulting in the breakdown of cytidine, cytosine riboside, a widely distributed nucleoside.
1 Q04179 (/IMP)
Uridine catabolic process GO:0006218
The chemical reactions and pathways resulting in the breakdown of uridine, uracil riboside, a ribonucleoside very widely distributed but occurring almost entirely as phosphoric esters in ribonucleotides and ribonucleic acids.
1 Q7KWM9 (/ISS)
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
1 P22564 (/IEP)
Pyrimidine-containing compound salvage GO:0008655
Any process that generates a pyrimidine-containing compound, any nucleobase, nucleoside, nucleotide or nucleic acid that contains a pyrimidine base, from derivatives of them without de novo synthesis.
1 Q04179 (/IMP)
Pyrimidine-containing compound salvage GO:0008655
Any process that generates a pyrimidine-containing compound, any nucleobase, nucleoside, nucleotide or nucleic acid that contains a pyrimidine base, from derivatives of them without de novo synthesis.
1 Q7KWM9 (/ISS)
Leaf senescence GO:0010150
The process that occurs in a leaf near the end of its active life that is associated with the dismantling of cell components and membranes, loss of functional chloroplasts, and an overall decline in metabolism.
1 Q8LAC4 (/IEP)
Nicotinate nucleotide salvage GO:0019358
The generation of nicotinate nucleotide without de novo synthesis.
1 Q04179 (/IGI)
NAD biosynthesis via nicotinamide riboside salvage pathway GO:0034356
The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD) from the vitamin precursor nicotinamide riboside.
1 Q04179 (/IGI)
Ribonucleoside catabolic process GO:0042454
The chemical reactions and pathways resulting in the breakdown of any ribonucleoside, a nucleoside in which purine or pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule.
1 P22564 (/IDA)
Purine-containing compound salvage GO:0043101
Any process that generates a purine-containing compound, any nucleobase, nucleoside, nucleotide or nucleic acid that contains a purine base, from derivatives of them without de novo synthesis.
1 Q4QDN1 (/IDA)
Purine-containing compound salvage GO:0043101
Any process that generates a purine-containing compound, any nucleobase, nucleoside, nucleotide or nucleic acid that contains a purine base, from derivatives of them without de novo synthesis.
1 P83851 (/TAS)
Pyrimidine nucleoside catabolic process GO:0046135
The chemical reactions and pathways resulting in the breakdown of one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).
1 Q04179 (/IDA)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
3 Q8LAC4 (/IDA) Q9P6J4 (/IDA) Q9SJM7 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q10314 (/IDA) Q9P6J4 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q10314 (/ISO) Q9P6J4 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q10314 (/ISO) Q9P6J4 (/ISO)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
1 Q9HGL1 (/IDA)