The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

Ribonucleoside hydrolase-like

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1987: Inosine-uridine preferring nucleoside hydrolase

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Ribosylpyrimidine nucleosidase. [EC:]
A pyrimidine nucleoside + H(2)O = D-ribose + a pyrimidine base.
  • Also hydrolyzes purine D-ribonucleosides, more slowly.
  • 2'-, 3'- and 5'-deoxynucleosides are not substrates.
527 A0A017IDG9 A0A023YZQ7 A0A024KWQ9 A0A024L1Q5 A0A025CFG1 A0A026RI27 A0A026UL30 A0A027U6B6 A0A027ZZM9 A0A028DLJ8
(517 more...)
Purine nucleosidase. [EC:]
A purine nucleoside + H(2)O = D-ribose + a purine base.
  • The enzyme from the bacterium Ochrobactrum anthropi specifically catalyzes the irreversible N-riboside hydrolysis of purine nucleosides.
  • Pyrimidine nucleosides, purine and pyrimidine nucleotides, NAD(+), NADP(+) and nicotinaminde mononucleotide are not substrates.
446 A0A017HHY2 A0A017HIW9 A0A024KAW0 A0A031IYG2 A0A034T3U8 A0A059E2J5 A0A059MXU0 A0A060HVP5 A0A060QCN2 A0A062X966
(436 more...)
Uridine nucleosidase. [EC:]
Uridine + H(2)O = D-ribose + uracil.
    29 A0A060TCG7 A0A073KSW5 A0A086ZHM7 A0A0C7P0T8 A0A0D3H356 A0A0E0IFR5 A0A0E0QMB7 A0A0E2PCL2 A0A0P7KJL9 A0A1C4BDX4
    (19 more...)
    Ribokinase. [EC:]
    ATP + D-ribose = ADP + D-ribose 5-phosphate.
    • 2-deoxy-D-ribose can also act as acceptor.
    1 W4LZJ8