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CATH Superfamily 3.50.50.60

FAD/NAD(P)-binding domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
FAD/NAD(P)-binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 112986: Squalene monooxygenase 1,2

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Transferred entry: 1.14.14.17. [EC: 1.14.13.132]
    		10 A0A0B7FFG8 A0A0E4FJ73 F2I9L3 I1V8B2 K7STL0 M5C5N1 U3LZY7 U3M083 U3M0H6 W1QL02
    Squalene monooxygenase. [EC: 1.14.14.17]
    Squalene + [reduced NADPH--hemoprotein reductase] + O(2) = (3S)-2,3- epoxy-2,3-dihydrosqualene + [oxidized NADPH--hemoprotein reductase] + H(2)O.
    • This enzyme, together with EC 5.4.99.7, was formerly known as squalene oxidocyclase.
    • The electron donor, NADPH, is coupled via EC 1.6.2.4.
    • Formerly EC 1.14.1.3, EC 1.14.13.132, EC 1.14.99.7 and EC 1.99.1.13.
    		 9 B9DFB1 O48651 O65402 O65404 O81000 P52019 P52020 Q3TQK8 Q8VYH2
    Transferred entry: 1.14.14.17. [EC: 1.14.99.7]
      		6 B7TWW5 B9S6Y2 B9SX91 G4T236 Q1KSF9 Q258Q8