CATH Superfamily 3.50.50.60

Browse Functional Families

ID	Function Family (FunFam) Name	Total Sequences	Enzyme?	Structure?	Structural Representative	PDB Sites?	Alignment Diversity (0-100)
112468	Succinate dehydrogenase, flavoprotein subunit	30768	EC	3D	1kf6A01	-	94.2
112809	Soluble pyridine nucleotide transhydrogenase	25266	EC		-	-	64.3
112565	D-amino acid dehydrogenase 2	19708	EC		-	-	96.8
113530	Geranylgeranyl diphosphate reductase BchP	18512	EC	3D	3oz2A01	-	96.6
112452	Alkyl hydroperoxide reductase subunit F	17523	EC	3D	1fl2A02	-	92.9
113557	Nitrite reductase large subunit	15224	EC		-	-	94.2
112733	Alkyl hydroperoxide reductase subunit	13823	EC	3D	1fl2A01	-	88.8
112787	Glutathione-disulfide reductase Gor	13582	EC	3D	1gerA01	-	67.3
112229	Mercuric reductase Hg(II	12261	EC	3D	1zk7A01	-	79.9
113436	Flavin-binding protein family monooxygenase	11730	EC	3D	1w4xA01	-	94.5
113158	Fumarate reductase flavoprotein subunit	9155	EC	3D	1d4cA02	-	91.6
112741	Probable L-aspartate oxidase nadB	9080	EC	3D	1knpA01	-	95.0
113610	Sarcosine oxidase subunit beta	7988	EC	3D	1vrqB01	-	87.6
113044	Probable malate:quinone oxidoreductase	7248	EC		-	-	89.9
113441	Probable glycerol-3-phosphate dehydrogenase, mitochondrial	7215	EC	3D	2rghA01	-	93.7
113138	FAD dependent oxidoreductase, putative	6769	EC		-	-	89.2
113575	Thioredoxin reductase	5995	EC	3D	1cl0A01	-	90.2
112570	Methylenetetrahydrofolate--tRNA- uracil-5-	5820	EC	3D	3g5qA01	-	93.8
113090	Methylenetetrahydrofolate--tRNA- uracil-5-	5528	EC		-	-	97.7
112567	Probable malate:quinone oxidoreductase 2	4640	EC		-	-	89.7
9767	Predicted oxidoreductase with FAD/NAD P	4602			-	-	15.5
113553	Toluene 1,2-dioxygenase system ferredoxin--NAD +	3975	EC		-	-	88.1
78176	3-phenylpropionate dioxygenase ferredoxin--NAD +	3945	EC		-	-	40.4
112693	2-octaprenyl-6-methoxyphenol hydroxylase, FAD/NAD P	3838			-	-	97.2
113784	N-methyltryptophan oxidase, FAD-binding	3778	EC		-	-	73.5
72451	Nitric oxide reductase FlRd-NAD	3742	EC		-	-	97.1
112736	Nitric oxide reductase FlRd-NAD	3581			-	-	80.4
113199	tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC	3488	EC	3D	3awiA02	-	93.8
10097	2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase	3267			-	-	76.0
112473	Dihydrolipoyl dehydrogenase	3085	EC	3D	1ebdA01	-	39.8
112932	Ferredoxin--NADP reductase 2	2935	EC	3D	3lzwA01	-	87.7
50216	L-lysine 6-monooxygenase [NADPH]	2612	EC		-	-	16.0
112069	Electron transfer flavoprotein-ubiquinone oxidoreductase	2364	EC		-	-	96.3
112903	Thiamine thiazole synthase, chloroplastic	2310	EC	3D	1rp0A02	-	94.6
112759	Soluble pyridine nucleotide transhydrogenase	2244	EC		-	-	73.5
111947	Dihydropyrimidine dehydrogenase subunit A	2191	EC		-	-	73.3
112550	Kynurenine 3-monooxygenase 2	2123	EC	3D	4j2wA00	-	87.6
112259	3- 3-hydroxy-phenyl	2048	EC		-	-	95.4
113911	Flavin-containing monooxygenase FMO GS-OX5	1772	EC		-	-	92.4
112819	Ferredoxin--NADP reductase	1768	EC		-	-	96.7
112456	Dihydrolipoyl dehydrogenase	1750	EC	3D	1lpfA01	-	72.4
64278	2,4-dienoyl-CoA reductase [NADPH]	1616	EC	3D	1ps9A03	-	63.6
112428	Thioredoxin and glutathione reductase	1510	EC	3D	2cfyA01	-	82.1
113097	Glutamate synthase, small subunit	1336	EC		-	-	86.2
113168	Glutathione reductase isoform 1	1308	EC	3D	2hqmA01	-	84.4
112785	Flavin-containing monooxygenase family protein	1257	EC		-	-	89.1
113558	Probable NADPH:adrenodoxin oxidoreductase, mitochondrial	1154	EC	3D	1lqtA02	-	91.9
113543	Probable NADH oxidase	1123	EC	3D	2bc0A01	-	79.6
113066	Probable L-aspartate oxidase nadB	1088	EC	3D	2e5vA01	-	91.5
113868	Sulfide dehydrogenase, flavoprotein subunit	967	EC	3D	1fcdA01	-	92.4
113012	Rab GDP dissociation inhibitor alpha	867	EC	3D	1ukvG01	-	84.9
113182	2,4-dienoyl-coa reductase Nadph	817	EC		-	-	90.7
4118	Succinate dehydrogenase, flavoprotein subunit	812	EC	3D	1zoyA01	-	88.2
111939	Thioredoxin reductase	754	EC	3D	2q0kA02	-	54.5
111672	Fumarate reductase flavoprotein subunit	682	EC	3D	1e7pA01	-	80.6
9226	Succinate dehydrogenase flavoprotein subunit	579	EC		-	-	59.0
112293	Dimethylaniline monooxygenase [N-oxide-forming] 1	579	EC		-	-	79.6
114026	Sulfide dehydrogenase, flavoprotein subunit	568	EC	3D	1fcdA02	-	98.9
112593	Dihydrolipoyl dehydrogenase, mitochondrial	564	EC		-	-	72.8
112735	Lysine-N-oxygenase MBTG L-lysine 6-monooxygenase Lysine N6-hydroxylase	559	EC		-	-	88.0
112483	4-hydroxybenzoate 3-monooxygenase	522	EC		-	-	80.7
113075	Putative cytosolic monodehydroascorbate reductase	507	EC	3D	5jciA01	-	86.7
112405	Ferredoxin--NADP reductase	490	EC		-	-	83.0
113474	Glutamate synthase small subunit	489	EC		-	-	91.0
112789	Ferredoxin--NADP reductase 3	488	EC		-	-	2.0
113721	Nitrite reductase NAD(P	479	EC		-	-	85.3
1667	Fumarate reductase flavoprotein subunit	469	EC		-	-	57.4
113130	Methylenetetrahydrofolate--tRNA- uracil-5-	446	EC		-	-	88.7
73879	Glutamate synthase, small subunit	399	EC		-	-	3.8
113929	Dihydrolipoyl dehydrogenase, mitochondrial	362	EC		-	-	95.7
112986	Squalene monooxygenase 1,2	357	EC		-	-	83.5
113763	Lysine-specific histone demethylase 1A	355	EC		-	-	85.0
113021	Ferredoxin--NADP reductase	310	EC		-	-	74.0
78468	Dihydrolipoyl dehydrogenase, mitochondrial	293	EC	3D	1zmcA02	-	75.6
113930	Monodehydroascorbate reductase II	291	EC	3D	5jciA02	-	87.5
113449	Amine oxidase [flavin-containing] A	284	EC	3D	2bxrA01	-	90.1
1243	Succinate dehydrogenase flavoprotein subunit	274	EC		-	-	5.9
111955	Flavin-containing monooxygenase FMO GS-OX5	273	EC		-	-	92.6
113272	Probable malate:quinone oxidoreductase	262	EC		-	-	92.6
113643	Prenylcysteine oxidase 1	261	EC		-	-	94.5
114154	Thioredoxin reductase, putative AFU_orthologue AFUA_5G03540	228	EC		-	-	96.0
112529	Dihydrolipoyl dehydrogenase, mitochondrial	216	EC	3D	1zmcA01	-	79.0
113325	Lycopene beta cyclase, chloroplastic	213	EC		-	-	93.7
23882	Predicted oxidoreductase with FAD/NAD P	211			-	-	42.1
113851	Lysine N6-hydroxylase/L-ornithine N5-oxygenase family protein	205	EC	3D	5cqfA00	-	95.0
112990	Peroxisomal N 1	204	EC		-	-	78.6
19214	Oxidoreductase	196			-	-	0.0
113576	Pyridine nucleotide-disulphide oxidoreductase, putative	188	EC		-	-	93.8
113007	Sulfide:quinone oxidoreductase, mitochondrial	186	EC		-	-	93.3
113405	3- 3-hydroxy-phenyl	180	EC		-	-	96.2
113996	Alcohol oxidase	179	EC		-	-	67.3
113477	FAD-dependent oxidoreductase domain-containing protein 2	178			-	-	74.6
113298	Sulfide:quinone oxidoreductase, mitochondrial	173			-	-	91.7
59439	Soluble pyridine nucleotide transhydrogenase	173	EC		-	-	12.0
44846	L-lysine 6-monooxygenase NADPH	170	EC	3D	3s5wA00	-	55.1
48177	Apoptosis-inducing factor 1, mitochondrial	170		3D	1gv4A02	-	79.3
112444	Putative rubredoxin reductase	169	EC		-	-	55.1
112643	Dihydrolipoyl dehydrogenase 1, mitochondrial	165	EC	3D	1dxlA01	-	70.5
113723	Sarcosine dehydrogenase, mitochondrial	161	EC		-	-	81.2
112355	Dihydrolipoyl dehydrogenase 3	154	EC		-	-	49.6
85488	Glutathione reductase, mitochondrial	154	EC	3D	1bwcA02	-	82.9
113829	Flavin-dependent tryptophan halogenase PrnA	138	EC		-	-	80.2
112073	Dihydrolipoyl dehydrogenase 2, chloroplastic	134	EC		-	-	58.4
113863	Amine oxidase [flavin-containing] B	124	EC		-	-	84.8
112505	Ferredoxin--NADP reductase 1	124	EC		-	-	67.6
112438	Dihydrolipoyl dehydrogenase	122	EC	3D	1lvlA01	-	36.9
112147	NADPH:adrenodoxin oxidoreductase, mitochondrial	121	EC	3D	1cjcA02	-	68.0
91916	Uncharacterized protein	121			-	-	0.0
113402	Trypanothione reductase, putative	117	EC	3D	1aogA01	-	74.9
113809	FAD-dependent oxidoreductase domain-containing protein 1	117			-	-	90.3
113635	Probable malate:quinone oxidoreductase	116	EC		-	-	75.2
113277	Amine oxidase [flavin-containing] B	115	EC	3D	1gosA01	-	40.3
112858	Anaerobic glycerol-3-phosphate dehydrogenase subunit B	110	EC		-	-	93.1
55890	Apoptosis-inducing factor 1, mitochondrial	103		3D	1gv4A01	-	70.9
113128	Ferredoxin--NADP reductase 1	102	EC		-	-	80.1
19606	Oxidative stress-induced growth inhibitor 2	95			-	-	73.1
112945	Uncharacterized oxidoreductase CzcO	93			-	-	55.1
112385	Dimethylaniline monooxygenase [N-oxide-forming] 4	86	EC		-	-	56.8
111571	KsdD-like steroid dehydrogenase Rv0785	75			-	-	60.7
111999	L-ornithine N5-oxygenase SidA	73	EC	3D	4b63A00	-	61.1
112322	FAD-dependent oxidoreductase domain-containing protein 2	72			-	-	60.9
114130	Probable malate:quinone oxidoreductase	71	EC		-	-	60.3
84037	Leucine-zipper-like transcriptional regulator 1	71			-	-	43.9
113050	Tetracenomycin polyketide synthesis hydroxylase TcmG	68	EC		-	-	84.5
112492	Ubiquinone biosynthesis monooxygenase COQ6	66			-	-	91.6
71797	Biphenyl dioxygenase system ferredoxin--NAD reductase component	64	EC		-	-	0.0
113501	Long-chain-alcohol oxidase FAO1	62	EC		-	-	79.9
64703	Dihydrolipoyl dehydrogenase	61	EC		-	-	17.1
6375	Succinate dehydrogenase/fumarate reductase flavoprotein subunit	59	EC		-	-	73.2
113114	Methylenetetrahydrofolate--tRNA- uracil-5-	59	EC		-	-	75.9
112445	Mercuric ion reductase	53	EC		-	-	14.2
63506	Dihydrolipoamide dehydrogenase lpdA	51	EC	3D	1xdiA01	-	21.8
112348	Dihydrolipoyl dehydrogenase	48	EC		-	-	38.8
113620	tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC	44	EC		-	-	92.9
74171	Dihydrolipoyl dehydrogenase	43	EC		-	-	13.7
112745	Dihydrolipoyl dehydrogenase 2	41	EC		-	-	57.2
114114	Flavin-containing monooxygenase	40			-	-	5.8
113427	Hydrogen cyanide synthase HcnC	39	EC	3D	1ng3A01	-	26.0
70358	Conserved protein	36			-	-	13.9
22655	Monooxygenase, FAD-binding	36			-	-	0.0
112968	Glutamate synthase small subunit	36	EC		-	-	71.9
113884	Nitrite reductase [NAD P	35	EC		-	-	93.9
112431	Glycerol-3-phosphate dehydrogenase subunit B	34	EC		-	-	28.1
113555	Thioredoxin reductase	32	EC		-	-	26.9
73213	Nitrite reductase [NAD P	29	EC		-	-	15.7
113801	Fructosyl amine: oxygen oxidoreductase	27		3D	4wctA01	-	60.3
104350	Polyamine oxidase	27		3D	1b37A01	-	2.0
67474	Dihydrolipoyl dehydrogenase	25	EC		-	-	5.5
39655	FAD monooxygenase, PheA/TfdB family	25	EC		-	-	0.0
12145	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	20	EC		-	-	20.3
112960	GDP dissociation inhibitor	20			-	-	48.7
113483	Salicylate 1-monooxygenase	19			-	-	92.3
112573	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	19			-	-	86.9
112878	Ferredoxin--NADP reductase 1	19	EC	3D	3ab1A01	-	51.9
112738	Ferredoxin--NADP reductase 1	18	EC		-	-	21.8
68574	Thioredoxin reductase 1, mitochondrial	18	EC	3D	2nvkX01	-	23.2
113383	Lysine N6-hydroxylase/L-ornithine N5-oxygenase family protein	17			-	-	60.8
55108	Oxidative stress-induced growth inhibitor 1	17			-	-	40.4
113482	Putative epoxidase LasC	16			-	-	49.9
113964	Uncharacterized protein R656	16			-	-	0.0
112678	N-methyl-L-tryptophan oxidase	16			-	-	22.5
112816	Ferredoxin--NADP reductase	16	EC		-	-	0.0
113429	Zeta-carotene desaturase, chloroplast, putative	16	EC		-	-	60.3
112763	Ferredoxin--NADP reductase 2	15	EC		-	-	72.4
112889	Coenzyme A disulfide reductase	15	EC		-	-	65.3
60322	Flavin-containing monooxygenase 1	14			-	-	38.6
113649	FAD dependent oxidoreductase superfamily protein	14			-	-	78.5
40215	Dimethylglycine dehydrogenase, mitochondrial	12	EC		-	-	12.3
35207	NADPH:adrenodoxin oxidoreductase, mitochondrial	11	EC		-	-	11.0
112527	NADPH dependent thioredoxin reductase	11	EC		-	-	32.9
113040	Ferredoxin--NADP reductase	11	EC		-	-	43.7
112314	Thioredoxin reductase	10			-	-	0.0
112822	Dihydrolipoyl dehydrogenase	10		3D	4jdrA01	-	21.2
112908	AIF-like mitochondrial oxidoreductase Nfrl	10			-	-	25.1
87383	Nitric oxide reductase FlRd-NAD +	10			-	-	17.9
50444	Pyridine nucleotide-disulphide oxidoreductase, putative	10			-	-	4.0
78132	Nitric oxide reductase FlRd-NAD +	10			-	-	20.2
113626	Rab proteins geranylgeranyltransferase component A	9			-	-	64.4
17452	2,4-dichlorophenol 6-monooxygenase	9	EC		-	-	51.5
113580	Nitrite reductase [NAD P	9	EC		-	-	36.9
30061	Monoamine oxidase maoN-Aspergillus niger	9			-	-	0.0
113262	Pentachlorophenol 4-monooxygenase	9			-	-	0.0
113735	FAD binding domain-containing protein	9	EC		-	-	79.4
113091	Dihydropyrimidine dehydrogenase [NADP +	8	EC		-	-	50.5
58041	Dihydrolipoyl dehydrogenase	8	EC		-	-	11.3
113960	L-lysine N6-monooxygenase MbtG	8	EC		-	-	39.6
113146	Rab proteins geranylgeranyltransferase component A	7			-	-	54.6
57852	2-enoate reductase FldZ	7	EC		-	-	16.5
113886	Methylenetetrahydrofolate--tRNA- uracil-5-	7	EC		-	-	66.2
113119	Dihydrolipoyl dehydrogenase	7	EC		-	-	57.8
14434	Geranyl geranyl reductase 2	6			-	-	5.7
16926	MRNA, complete cds, clone: RAFL25-42-E03	6			-	-	27.1
103321	Spermine oxidase	6			-	-	18.8
58833	Dihydrolipoyl dehydrogenase, mitochondrial	6	EC		-	-	8.1
113018	Ferredoxin--NADP reductase	5	EC		-	-	0.7
113713	Tetracycline resistance protein	5			-	-	4.3
84686	Pyridine nucleotide-disulphide oxidoreductase, putative	5	EC		-	-	9.6
112067	Opine oxidase subunit B	5			-	-	16.8
113946	FAD-dependent pyridine nucleotide-disulfide oxidoreductase family protein	4			-	-	0.0
113286	Succinate dehydrogenase, flavoprotein subunit	4	EC		-	-	31.9
19583	L-aspartate oxidase	4	EC		-	-	0.0
49710	L-lysine 6-monooxygenase domain protein	4	EC		-	-	22.8
33940	Oxidoreductase	4			-	-	0.0
56386	Pyridine nucleotide-disulfide oxidoreductase domain 1	4			-	-	0.0
113687	Anaerobic glycerol-3-phosphate dehydrogenase subunit B	4	EC		-	-	0.0
66518	Pyridine nucleotide-disulfide oxidoreductase family protein	4	EC		-	-	6.9
15506	L-aspartate oxidase	4	EC		-	-	0.0
73385	Ferredoxin--NADP reductase	4	EC		-	-	3.7
35500	Putative thiamine biosynthesis oxidoreductase ThiO	4			-	-	0.0
113058	Apoptosis-inducing factor 2	3			-	-
82972	Alkyl hydroperoxide reductase subunit F	3			-	-	25.9
31732	Pyruvate dehydrogenase phosphatase regulatory subunit	3			-	-	22.8
92381	Sarcosine dehydrogenase, mitochondrial	3			-	-	23.8
66919	Rhizobactin siderophore biosynthesis protein RhbE	3	EC		-	-	0.5
112705	Toluene 1,2-dioxygenase system ferredoxin--NAD +	3		3D	3ef6A01	-	0.0
50942	Thioredoxin reductase	3			-	-	0.7
111648	L-aspartate oxidase	2	EC		-	-	9.7
113779	Methylenetetrahydrofolate--tRNA- uracil-5-	2	EC		-	-	37.3
107784	Glucose oxidase goxC-Aspergillus niger [putative sequencing error] ANG_orthologue An01g14740	2			-	-	0.0
113847	Opine oxidase subunit A	2			-	-	17.4
67614	Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1	2			-	-	13.2
82579	Nitric oxide reductase FlRd-NAD +	2			-	-	0.0
6443	Flavocytochrome c, flavin subunit	2	EC		-	-	0.4
6148	ENSANGG00000008286-like	2			-	-	14.1
29404	Gdp dissociation inhibitor family protein	2			-	-	4.6
18618	Dimethylaniline monooxygenase [N-oxide-forming] 4	2	EC		-	-	15.8
113105	Thioredoxin reductase	2			-	-	15.2
23114	At5g39940	2			-	-	4.5
65800	Dihydrolipoyl dehydrogenase	2	EC		-	-	1.7
113480	Putative thioredoxin reductase	2	EC		-	-	39.9
113268	Probable tryptophan hydroxylase VioD	2	EC		-	-	39.8
67334	Dihydrolipoyl dehydrogenase	2	EC		-	-	0.0
50886	Anaerobic glycerol-3-phosphate dehydrogenase subunit B	2	EC		-	-	21.2
143	Cellobiose dehydrogenase	2	EC		-	-	0.0
63509	Dihydrolipoyl dehydrogenase	2	EC		-	-	0.0
113101	Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1	2			-	-	14.2
113430	Mercuric reductase Hg(II	2	EC		-	-	18.1
105787	Glucose oxidase	2		3D	1gpeA01	-	0.0
113612	Dimethylaniline monooxygenase [N-oxide-forming] 4	2			-	-	0.0
113546	Methylenetetrahydrofolate--tRNA- uracil-5-	2	EC		-	-	19.6
70692	Mercuric reductase	2	EC		-	-	9.1
112440	Lycopene cyclase	2			-	-	0.0
83883	Nitric oxide reductase FlRd-NAD +	2			-	-	2.6
83025	Putative mercuric reductase	1	EC		-	-	0.0
15733	Ferredoxin--NADP reductase	1	EC		-	-	0.0
68016	Dihydrolipoyl dehydrogenase	1	EC		-	-	0.0
36866	Myosin-cross-reactive antigen	1	EC		-	-	0.0
112064	Soluble pyridine nucleotide transhydrogenase	1	EC		-	-	0.0
16484	L-aspartate oxidase	1	EC		-	-	0.0
79695	NADH:flavin oxidoreductase/NADH oxidase	1			-	-	0.0
113329	Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1	1			-	-	0.0
112731	Salicylate hydroxylase	1			-	-	0.0
37002	Uncharacterized protein	1			-	-	0.0
104920	Glucose dehydrogenase [FAD, quinone]	1			-	-	0.0
36097	Fructosyl-amino acid oxidase, putative	1			-	-	0.0
113715	Choline dehydrogenase	1			-	-	0.0
82118	Rubredoxin-NAD +	1	EC		-	-	0.0
91948	Putative uncharacterized protein	1			-	-	0.0
112554	Anaerobic glycerol-3-phosphate dehydrogenase subunit B	1	EC		-	-	0.0
54915	Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial	1			-	-	0.0
100427	Podospora anserina S mat+ genomic DNA chromosome 1, supercontig 1	1			-	-	0.0
113034	FAD/NAD P	1			-	-	0.0
63396	L-lysine 6-monooxygenase domain protein	1	EC		-	-	0.0
113683	Thioredoxin reductase	1	EC		-	-	0.0
95736	Lysine-specific histone demethylase 1B	1			-	-
77624	NADH-dependent phenylglyoxylate dehydrogenase subunit epsilon	1	EC		-	-	0.0
90246	Tetraacyldisaccharide 4'-kinase	1	EC		-	-	0.0
5481	Putative adenylylsulfate reductase, alpha subunit	1			-	-	0.0
113707	NADH-dependent phenylglyoxylate dehydrogenase subunit epsilon	1			-	-	0.0
113442	Predicted protein	1			-	-	0.0
91012	Dihydrolipoyl dehydrogenase	1	EC		-	-	0.0
105862	FAD-dependent oxidoreductase domain-containing protein 1	1			-	-	0.0
113389	Apoptosis-inducing factor, mitochondrion-associated, 3	1			-	-
112441	Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2	1			-	-
92726	Ferredoxin--NADP reductase 1	1	EC		-	-	0.0
16144	Uncharacterized FAD-dependent oxidoreductase MJ0033	1			-	-	0.0
113997	FAD-dependent monooxygenase, putative AFU_orthologue AFUA_7G00150	1			-	-	0.0