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CATH Superfamily 3.50.50.60

FAD/NAD(P)-binding domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
FAD/NAD(P)-binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 112565: D-amino acid dehydrogenase 2

There are 5 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
D-arginine dehydrogenase. [EC: 1.4.99.6]
D-arginine + acceptor + H(2)O = 5-guanidino-2-oxopentanoate + NH(3) + reduced acceptor.
  • The enzyme, which has been isolated from the bacterium Pseudomonas aeruginosa PAO1, forms with EC 1.4.1.25 a two-enzyme complex involved in the racemization of D- and L-arginine.
  • The enzyme has a broad substrate range and can act on most D-amino acids with the exception of D-glutamate and D-aspartate.
  • However, activity is maximal with D-arginine and D-lysine.
  • Not active on glycine.
  • Formerly EC 1.4.99.1.
 73 A0A089HBU2 A0A0C6P3P0 A0A0D6FTG4 A0A0F6B2A4 A0A0F6LQ99 A0A0F7DIP9 A0A0H3NM23 A0A0L4MRY5 A0A0M0QT60 A0A0R9PDT7
(63 more...)
Transferred entry: 1.4.99.6. [EC: 1.4.99.1]
    		22 A0A031GEW8 A0A0D1EBY8 A0A0D1EDW5 A0A0D1EXR9 A0A0F6LQ99 A0A0I1C8W1 A0A0J1FHC9 A0A0M2ICS1 A0A1L2ETK8 A0A1N7U5T1
    (12 more...)
    Glycine oxidase. [EC: 1.4.3.19]
    Glycine + H(2)O + O(2) = glyoxylate + NH(3) + H(2)O(2).
    • The enzyme from Bacillus subtilis is active with glycine, sarcosine, N-ethylglycine, D-alanine, D-alpha-aminobutyrate, D-proline, D-pipecolate and N-methyl-D-alanine.
    • It differs from EC 1.4.3.3 due to its activity on sarcosine and D-pipecolate.
    • The intermediate 2-iminoacetate is used directly by EC 2.8.1.10.
    		 3 A0A0C6P3P0 A0A1M9JYV6 Q7WI07
    Alanine racemase. [EC: 5.1.1.1]
    L-alanine = D-alanine.
      		 1 A0A0G2NM01
      Sarcosine oxidase. [EC: 1.5.3.1]
      Sarcosine + H(2)O + O(2) = glycine + formaldehyde + H(2)O(2).
      • The flavin is both covalently and non-covalently bound in a molar ratio of 1:1.
      		 1 A0A0I1C8W1